Cardiopulmonary Flashcards
Kawasaki disease
Asian children < 4 yo
Acute (1-2 wks):
- Fever
Subacute (2-4 wks):
- desquamation
- thrombocytosis
- coronary aneurysms
- highest risk of death
Convalescent (6-8 wks)
- clinical signs gone
- ESR nl
Other sx:
- Cervical lymphadenitis (usually unilateral)
- Conjunctival injection
- Strawberry tongue
- Hand-foot erythema
- Desquamating rash
Complications:
Coronary aneurysms –> MI (2nd-3rd wk)
Tx:
- IV Ig
- ASA
Churg Strauss syndrome
Vasculitis
Asthma
Sinusitis
Palpable purpura
Peripheral neuropathy
+ pANCA
increased IgE
Henoch-Schonlein purpura
Most common childhood systemic vasculitis
Often follows URI
Peak age 4-8yo
Vasculitis 2/2 IgA complex deposition in small vessels
Classic triad:
- Skin –> palpable purpura (butt + legs)
- Arthralgias
- GI –> pain, melena
- *GI pain can be 2/2 GI bleed or Intussusception
Most lab tests normal
Coag studies normal
Tx:
- supportive (self limited)
- steroids for GI and CNS complications
Cystic hygroma
Cavernous lymphangioma of neck
Assoc w/ Turner syndrome
Sturge Weber disease
Congenital vascular d/o affecting capillary sized blood vessels
- Port wine stain on face
- ipsilateral leptomeningeal angiomatosis (intracerebral AVM)
- seizures
- early onset glaucoma
Choanal atresia
Septum between nose and pharynx
High association with CHARGE syndrome
- Coloboma
- Heart dz
- Atresia choanae
- Retarded growth
- GEnital anomalies (hypogonadism)
- Ear anomalies (deafness)
Presentation
- cyanosis w/ crying
- newborns are basically nose breathehrs
Epistaxis
1 cause = picking nose
Nosebleed, usually from anterior septum
Also consider juvenile nasopharyngeal angiofibroma in pubertal boys
Most common sites for foreign body
< 1 yo = larynx
> 1 yo = trachea and bronchi (esp R main stem bronchus)
Asthma
Reversible obstructive airway disease affecting small and large airways
3 components to attack:
- bronchospasm
- mucous production
- airway edema
Dx:
- eosinophilia in blood and sputum
- allergy skin testing to ID environmental allergens
- PFTs
- increased lung markings on CXR; also hyperinflation and atelectasis
You start as respiratory alkalosis first and then turn into respiratory acidosis
Tx asthma
Short acting beta agonist (not regularly though)
Long acting beta agonist (daily controller)
Mild intermittent asthma
Sx =< 2x / wk
Night sx =< 2x / month
Daily meds not needed
Tx flares with inhaled or systemic steroids if necessary
Mild persistent asthma
Sx > 2x / wk
Night sx > 2x / month
Need daily:
- low dose steroid vs cromolyn
- Short acting beta agonist prn
Moderate persistent asthma
Daily sx
Asthma exacerbation >= 2s / wk
Need daily:
- Low dose inhaled steroids (vs lekotriene receptor antagonist) + LABA
OR
- medium dose inhaled steroids
Severe persistent asthma
Continual sx
Frequent exacerbation
Need daily:
- high dose ICS + LABA
Tx exercise induced asthma
Prevent by B2-agonist immediately before exercise
Ddx wheezing
Asthma CF Postinfectious Infectious CHD Ciliary dyskinesia Chronic aspiration FOreign body Immunodeficiency Congenital airway anomaly Extrinsic airway compression
Tx apnea
Adenotonsillectomy
3 types of apnea
Central - lack of respiratory effort
Obstructive - total airway obstruct
Mixed
Types of mixed apnea
Apnea of prematurity
- preemies < 30 wks old
- bradycardia
- Tx: theophylline or caffeine or intubation
Cyanotic breath holding
- < 3 yo
- hold breath because of anger
- tx = reassurance
Pallid breath holding
- happens after painful stimulus
- turn pale and have asystole and seizure
- Tx = atropine
Obesity hypoventilation
- 2/2 airway obstruction
- obesity
- somnolence
- polycythemia
- cor pulmonale
- Tx: weight loss
Sudden infant death syndrome
#1 cause of death in infants 1-12 mo of age Peak at 2-3 mo age
Prevention:
- sleep on back
- electronic monitoring of HR, respiratory pattern, oxygenation
An innocent murmur is never…
Diastolic
> 2/6
Acyanotic heart disease
L —> R shunting
VSD ASD PDA Endocardial cushion defects Coartctation of aorta
Harsh holosystolic murmur at left lower sternal border
VSD
EKG changes seen in large VSD
BIventricular hypertrophy
NOtched peaked P waves
Tx VSD
Usually small defects close
Abx to ppx endocarditis
Surgery for large defects w/ pulm HTN that has not yet become severe
ASD - most common type
Ostium secundum most common
Systolic ejection murmur in left mid and upper sternal border
Wide fixed split S2
ASD
Complications of ASD
Sx usually appear in 30s
Endocarditis rare - ppx not recommended
Wide pulse pressure
Bounding arterial pulses
Machinery continuous murmur
PDA
wide PP and bounding arterial pulses happen in large PDA
Associations of PDA
Maternal rubella
Prematurity
CXR PDA
Prominent pulm A
INcreased pulm vascular markings
Tx PDA
Indomethacin
Spontaneous closure
- but rare to close after infancy so need surgery
Risk of endocarditis and CHF if don’t close
What is an endocardial cushion defect?
ASD and VSD occur and are continuous
AV valves also abnormal
Higher risk with trisomy 21
Complications of large AV defects
Heart failure early in infancy
Eisenmenger
LAD
Death 2/2 heart failure
Heart block 2/2 surgery
ALWAYS DO SURGERY ON THESE!
Most coarctations of aora occur
Just below origin of L subclavian A
More common in boys
Increased incidence in Turner
CXR of coarctation of aorta
Cardiac enlargement
pulm vascular markins
Rib notching in older kids