Cardiomyopathy Flashcards
What drug causes dilated cardiomyopathy?
doxorubicin
What type of dysfunction of dilated cardiomyopathy cause?
systolic dysfunction
Women can get dilated cardiomyopathy due to…
pregnancy
3 types of cardiomyopathy
dilated (systolic dysfunction)
hypertrophic (diastolic dysfunction)
restricted (diastolic dysfunction)
How does dialated cardiomypathy affect valves?
can cause aortic insufficiency
pulls valve leaflets apart
Hypertrophic cardiomyopathy
pathology
massive hypertrophy of left ventricle
Typical case of hypertrophic cardiomyopathy
young athlete that drops dead
Biopsy of heart from hypertrophic cardiomyopathy
“myofiber hypertrophy with disarray”
fibers going all different directions
Syncope in hypertrophic cardiomyopathy
hypertrophy of ventricular septum can block off opening to aortic valve
Classic finding of restrictive cardiomyopathy
low-voltage EKG with dimished QRS amplitude
Restrictive cardiomyopathy
pathology
decreased compliance of the ventricular endomyocardium
restricts filling during diastole
ie amyloidosis, sarcoidosis, endocardial fibroelastosis (children), Loeffler syndrome (endomyocardial fibrosis with eosinphilic infiltrate and eosinophilia)