Cardiomyopathies Flashcards
Organic solvent that causes DCM
Toluene
3 chemo therapies that can cause DCM
Daunoribicin Doxorubicin Sunitinib Trastuzumab Cyclophosphamide Bleomycin
Party drugs that can cause DCM
ETOH
Cocaine
Heavy metals that can cause DCM
Mercury
Lead
Cobalt
Antiretrovirals that can cause DCM (3)
Zidovudine
Didanosine
Zalcitabine
Time frame for peripartum CM
Last month of pregnancy to 5 mo’s after
Risk factors for peripartum CM
Age> 30 Multiparity AA h/o preeclampsia or postpartum HTN cocaine
Drug of choice in pregnant women instead of ACEI
hydralazine
Population at risk of Takotsubo
Percent risk of ventricular arrhythmias?
Postmenopausal women
15%
Recurrence rate for Takotsubo
4%
Bugs causing HIV focal myocarditis
HIV CMV EBV coxsackie Toxoplasma
Inheritance pattern of muscular dystrophies.
Which is worse (Becker’s or Duchenne’s) for CM?
X-linked
Becker’s
When should you suspect anthracycline induced CM (daunorubicin)?
Risk factors
Dose dependent> 550mg/m2
3-12 months after.
Can occur upto 10y later
DM, HTN,
If high doses of daunorubicin needed,what med to give to avoid CM?
Dexrazoxane, ACEI, BB
Difference in LVEDD b/w HCM and athlete
HCM: LVEDD <45
What type of activity is OK with HCM?
Low level
3 factors making SAM worse in HOCM
Increased contraction
Decreased resistance (vasodilator)
Decreased volume
Preferred Rx in HOCM (myomectony vs. septal ablation)
Myomectony