cardiology2 Flashcards
Quinidine
class 1a Na channel blocker, also blocks K particularly well, thereby prolonging action potential duration and it is a vagal inhibitor (anti-cholinergic) as it is a alpha-adrenergic receptor.
Procainamide
class 1a Na channel blocker
Disopryamide
class 1a Na channel blocker
Lidocaine
most important class 1b Na channel blocker in treating arrhythmias, shortens phase 2, increases refractory period.
Mexiletine
class 1b Na channel blocker, shortens phase 2, increases refractory period.
Phenytoin
class 1b Na channel blocker, shortens phase 2, increases refractory period.
Propafenone
class Ic Na channel blockers
Flecainide
class Ic Na channel blockers
Encainide
class Ic Na channel blockers, no longer marketed
Propranolol
beta blocker (class II), reduces L-type Ca current and K current.
Metoprolol
beta blocker (class II), reduces L-type Ca current and K current.
Esmolol
beta blocker (class II), reduces L-type Ca current and K current.
Ibutilide
K channel blockers (class III)
Dofetillide
K channel blockers (class III)
Amiodarone
K channel blockers (class III), also markedly reduces conduction velocity and increases refractory period by blocking Na channels. Also decreases the rate of diastolic depolarization (phase 4) in automatic cells, thus reducing firing rate
Sotalol
K channel blockers (class III), is also a beta blocker
Bretylium
K channel blockers (class III)
Verapamil
use dependent blockers of L-type Ca channels.
Ditiazem
use dependent blockers of L-type Ca channels.
Lisinopril
ACEI
Enalapril
ACEI
Benazepril
ACEI
Valsartan
ARB
Candesartan
ARB