Cardiology Flashcards
Diagnostic Investigation for aortic stenosis
Echo
Ejection systolic murmur best heard at the 2nd right intercostal space, at the right sternal border which radiates to the carotid arteries,
Aortic stenosis
Aortic stenosis
Murmur is accentuated when sits upright
most common valvular heart disease in the UK
Elderly patient with exercise intolerance
or maybe asymptomatic
Aortic stenosis
respiratory alkalosis
Pulmonary embolism
initial investigation for PE
CTPA (CT pulmonary angiogram)
if CTPA cant be performed(renal impairment or allergy to contrast media)
V/Q scan
PE
Immediate administration of DOAC once PE is suspected (even prior to CTPA)
ECG changes in PE
S1Q3T3
SINUS TACHYCARDIA
Gold standard investigation PE
Pulmonary angiography (but CTPA has replaced it now)
First line treatment for most PE+ pts with active cancer
DOACS (apixaban or rivoraxaban)
3-6months
Pt with PE + severe renal impairment{15/antiphospholipid syndrome
LMWH + warfarin
first line treatment when there is massive PE when there is circulatory failure (hypotension)
Thrombolysis
wells score >4 ➝
Immediate CTPA
wells score ≤4 ➝
D-dimer test, if +ve ➝ Immediate CTPA
absolute CI to thrombolysis
CNS neoplasm,aortic dissection,stroke less than 3 months,active internal bleeding
Chest pain often relieved by sitting forwards
•Worsened by inspiration, lying flat, cough, swallowing, or movement of the trunk
Pericarditis
ECG changes in pericarditis
Saddle shaped ST elevation(upward concavity)
PR segment depression-most specific ecg marker for pericarditis
ECG J waves
hypothermia
ECG U waves
hypokalemia
Nicorandil
ivabradine ranolazine
Used for angina. its a potassium channel activator.
First line treatment for angina
Calcium channel blocker or beta blocker
Ivabradine
reduces heart rate(visual effects)
Transient ischaemic attack(facial weakness 4days ago now fine)
Immediate treatment: aspirin + urgent referral to specialist (24hr) further management: Clopidogrel (first line) Carotid endarterectomy (}}70% stenosis)
Presents as palpitations(300-400) ECG: An irregularly irregular pulse • Absent P wave irregular QRS complex variable R-R intervals
Atrial fibrillation
A fib + Hemodynamically unstable
Immediate DC cardioversion
or pharmacologic cardioversion
A fib Patient is hemodynamically stable
1st choice → beta-blockers or CCB (diltiazem or verapamil)
• Digoxin is used if there’s CHF
• Thromboprophylaxis is also used(warfarin plus NOACs)
Pansystolic murmur at apex 5th (intercostal space, left midclavicular line) which radiates to the axilla
Mitral Regurgitation
2-10 days post MI and the patient is
presented with pulmonary edema or after rheumatic fever. struggles to lie flat at night
Mitral Regurgitation
Left ventricular failure: dyspnea, orthopnea and paroxysmal nocturnal dyspnea
severe MR → right sided heart failure → edema and ascites
Anticoagulation after A fib(lifelong) if chads score greater) age hypertension previous stroke etc
Warfarin or NOAC
Aspirin is not recommended for reducing stroke risk in patients with A fib
Anaphylactic reaction
IM adrenaline O.i5 0.3 0.5 anterolateral aspect of middle third of thigh
give 2 inj 1:1000
no relationship b/w P waves and QRS complex
Third degree block. Cannon waves in neck. Rx pacemaker
Fondaparinux
activates antithrombin 3
Most suitable initial investigation for someone having syncopial attacks
ECG
ECG old MI
persistent Q waves
MI ECG
Hyperacute T waves:first change
ST elevation:minutes–hours
Q waves:hour—indefinitely
T wave inversion:first 24 hours to few days
RBBB
MarroW V1 and V6
LBBB
WilliaM V1 and V6
Wolf Parkinson white
Delta waves
warfarin
inhibits reduction of vit k (1972c)
CI in pregnancy but allowed while breastfeeding
target inr 2.5 (if recurrent 3.5)
SE: hemorrhage,purple toes,skin necrosis
Management when INR is high
Major bleeding stop warfarin give IV vit K PCC or FFP
Chest pain radiating to back
Hypertension
Mediastinal widening on CXR
Assymetry of pulses
Aortic Dissection
target BP for a well-controlled diabetic
140/90
First line management of heart failure
ACE I and beta blockers(decrease mortality)
Rx of CCF
Please note acute management is different
ACE I and beta blockers(decrease mortality)
1st line → ACE-inhibitor and beta-blocker (e.g. Carvedilol)
- DM or signs of fluid overload → start with ACE-inhibitor
- Ejection fraction ≤40% → start with ACE-inhibitor
- Angina → start with beta-blocker
• 2nd line → Spironolactone )
• manegement of symptoms : furosemide
Digoxin → Heart failure + Atrial Fibrillation
alternative agent: ivabradine
1st line blood test for heart failure
NT-proBNP
high above 2000 specialist review and echo within two weeks
PLAB tip
Do NOT combine ARB and ACE I
DVLA
post MI can not drive for 4 weeks
htn continue driving
angioplasty 1 week
CABG 4 wks
post ACS 4 wks 1 wk if sucsfl angioplasty
angina- driving must cease if symptoms occur at rest
pacemaker insertion 1 wk
defibrillator 1 month to 6 months
catheter ablation post arrythmia 2 days off
aortic aneurysm more than 6.5 cm cease driving
ACE I SE
cough
hypotension(diuretics,aortic stenosis)
angioedema
hyperkalemia
hypertrophic cardiomyopathy
autosomal dominant disorder
hypertrophic cardiomyopathy
ejection systolic murmur increases on valsalva maneuver
hypertrophic cardiomyopathy ECHO
MR SAM ASH
Antibiotic prophylaxis for IE
not routinely recommended in the UK
Fever + new murmur
Endocarditis until proven otherwise
IE MC Causative organisms:
Staph aureus(IVDU) Strept viridians(developing countries)(dental hygiene) Staph epidermidis- prosthetic heart valves
IE DX
BE FIVE PM
IE RX
amoxicillin + gentamicin
MRSA or penicillin allergy: vancomycin + gentamicin
Prosthetic valves; vancomycin + gentamicin + rifampicin
bendroflumethiazide
no longer used diuretic for HTN
a girl on microgynon30,chest pain, SOB,cough,tachcardia ecg s1q3t3
(alternatively a history of long travel or immobilisation can be given)
Pulmonary Embolism
absent left radial pulse
Takayasu Arteritis