Cardiology Flashcards
Which ECG leads correspond to the lateral surface of the heart?
I, aVL, V5, V6
Circumflex artery
Which ECG leads correspond to the inferior surface of the heart?
II, III & aVF
Right coronary artery
Which ECG leads correspond to the septal area of the heart?
V1, V2
Left anterior descending artery
Which ECG leads correspond to the anterior surface of the heart?
V3, V4
R coronary artery
What are some non-modifiable risk factors for ACS?
Increased age
Male
Family history
What are some modifiable risk factors for ACS?
Smoking
Diabetes mellitus
Hypertension
Physical inactivity
What is a STEMI?
Cardiac chest pain with persistent ST elevation
Hs-TnI >100ng/L
What is an NSTEMI?
Cardiac chest pain
Normal ECG, ST depression or T wave inversion
Raised his-TnI
What is unstable angina?
Cardiac chest pain
Normal ECG, ST depression or T wave inversion
Normal troponin
What symptoms would indicate ACS?
Pain in chest, may radiate to jaw, back etc. New onset, or occurring with little exertion in pts with angina
Nausea and vomiting
Sweating
Breathlessness
What investigations are required for suspected ACS?
12 lead ECG Cardiac enzymes FBC - rule out anaemia U&Es - inc K+ can cause arrhythmias Lipid profile Random blood glucose, HbA1c Blood gases - monitor oxygen levels
What is the initial management for a STEMI?
IV morphine, with an anti-emetic
Oxygen if hypoxic - aim for >94%
300mg aspirin
60mg prasugrel or 600mg clopidogrel
What is the definitive treatment for a STEMI?
Primary PCI
What drugs should be started after a STEMI?
ACE inhibitor or ARB
Aspirin
Bisoprolol
Statin
What is initial management of an NSTEMI?
Pain relief
Oxygen if hypoxic
300mg aspirin, 180mg ticagrelor
Low molecular weight heparin
When should a pt with NSTE-ACS be offered angiography?
High risk from GRACE score
Low risk, but Sx are recurring
What are some ischaemic complications of an MI?
Reocclusion
Infarction in a separate territory
Post-infarction angina
What are some mechanical complications of an MI?
Left ventricular dysfunction Left/right heart failure Ventricular septal rupture Free wall rupture Acute mitral regurgitation
What is the drug treatment for stable angina?
75mg aspirin Sublingual GTN β-blocker Non-dihydropyridine CCB (diltiazem, verapamil) Statin
What are some non-cardiac causes of chest pain?
Costochondritis GORD Cholecystitis Acute pancreatitis Pneumonia PE
What are some causes of secondary hypertension?
Renal disease
Cushing’s syndrome
Conn’s syndrome
Pregnancy
How is hypertension defined?
Stage 1 - clinic 140/90mmHg, home/ambulatory 135/85mmHg
Stage 2 - clinic 160/100mmHg, home/ambulatory 150/95mmHg
Severe - 180mmHg systolic, 110mmHg diastolic
How can HTN present?
Usually asymptomatic
Headache
Sweating, palpitations, anxiety => phaeochromocytoma
Muscle weakness, tetany => hyperaldosteronism
What investigations are done to assess for end organ damage in hypertension?
Urine albumin:creatinine ratio Haematuria Bloods - HbA1c, electrolytes, creatinine, eGFR, total cholesterol, HDL Fundoscopy 12 lead ECG