Cardiology Flashcards
Definition of unstable angina
Pain comes on at rest, negative troponins, no change on ecg
Definition of stable angina
Pain comes on by exercise/emotion, relieved by rest. negative troponins and no ecg changes
Things to ask about in chronic history
OPTICPR Onset Presentation Treatment Investigations Complications Progression Recovery
Associated symptoms of ischemic heart disease
Nausea, vomiting, dyspnoea,sweating, exercise tolerance, relieved by GTN
Background info with ischemic heart disease
Hospital admissions
Procedures-angioplasty, thrombolysis, stents (drug eluting/bare metal)
Medications started
Complications (arrhythmias/ heart failure/embolic events)
Participation in cardiac rehab program
Risk factors for ischemic heart disease
Previous IHD Hyperlipidemia DM Hypertension Smoking OCP Family history Obesity Physical inactivity
Differentials for IHD
GORD
Oesophageal spasm
PE
MSK
Investigations for IHD
ECG Troponins (usually don't rise until 6 hours post so order a repeat. Remain elevated for 2 weeks) Exercise tolerance test ECHO Angiogram
Immediate management of angina
Stable: GTN spray (caution with sildenafil) consider BBlockers
Unstable: Aspirin, GTN, consider BBlockers
Acute Management of STEMI
Morphine, GTN, O2 (if hypoxic), aspirin, ticagrelor, metoclopramide
Patients presenting within 12 hours consider for PCI
Otherwise thrombolysis with IV tenecteplase
Admit to CCU
Acute management of Non-stemi
Morphine, GTN, O2 (if hypoxic), aspirin, ticagrelor, metoclopramide
Admit to CCU
Secondary prevention of IHD
Pharmacological: consider BBlockers, Statins, ACE inhibitors, aspirin forever, ticagrelor for one year, nitrates
Indications for CABG?
Three vessel disease
Significant LAD stenosis
Significant left main coronary artery stenosis
Classic presentation of infective endocarditis
Fever, acute heart failure, new murmur
Risk factors for infective endocarditis
Recent dental, endoscopic, or operative procedure, valve disease, rheumatic fever, heart disease, IV drug use, immunosuppression
Most commonly affected valve in infective endocarditis
Mitral (mitral regurgitation) caused by strep viridans
How to diagnose infective endocarditis
Duke's criteria Major 1. Typical organism on 2x blood cultures 2.Evidence of endocardic involvement on echo Minor 1. Predisposing cardiac condition/IV drug use 2. Fever >38 3. Vascular phenomena 4. Positive blood culture 5. Echo abnormality
Differentials for infective endocarditis
Rheumatic fever
Atrial myxoma (tumour)
SLE
Investigations for infective endocarditis
Bloods: Cultures for staph aureus and Step viridans
Check for inflammatory markers (FBC and ESR will be high)
Imaging: CXR (HF, cardiomegaly) ECHO
MSU (haematuria from emboli)
Management for infective endocarditis
IV antibiotics dependent on organism sensitivities
4 weeks but 6-8 weeks if prosthetic valves
Consider cardiac surgery
Consider antibiotic prophylaxis
What are the key formulae for the physiology of heart failure
Cardiac output= Stroke Volume x Heart Rate
Stroke Volume= diastolic volume-end systolic volume
Mean arterial pressure= diastolic pressure + 1/3pulse pressure
Difference in symptoms between left and right heart failure on history
Left: dyspnoea and poor ETT Orthopnea/PND Wheeze Nocturia Cold peripheries Pink frothy sputum Right: peripheral oedema ascites nausea (biliary congestion) facial engorgement epistaxis