Cardiology Flashcards
ACS | Investigations
DDx high troponin
ECG changes
Troponin; repeat after 6hrs, in 1000s
DDx: pericarditis, myocarditis, arrhythmias, PE
ECG; STEMI, new LBBB, pathological Q waves, T wave inversion/flattening/elevation
CXR to look for cardiomegaly, pulmonary oedema, widened mediastinum (aortic rupture)
Chest pain | Differentials
Cardiac
Non-cardiac
[Cardiac] ACS; nausea/vomiting, sweating, SOB, occurring at rest Stable angina; exertional Aortic dissection Pericarditis/cardiac tamponade Myocarditis Acute CCF Arrhythmias
[Respiratory]
PE
[Other] Acute pancreatitis Oesphageal rupture GORD/PUD Oesphagitis/oesphageal spasm Acute cholecystitis Rib # Costochondritis Anxiety
ACS | Management
Acute, MONAC
Secondary prevention
Modifiable risk factors
General advice
[Acute] (Oxygen, if hypoxic) Sublingual GTN IV morphine Aspirin 300mg Revascularisation with PCI <90mins Or thrombolysis >90mins and transfer to primary PCI centre
[Secondary prevention]
Modifiable risk factors
Dual antiplatelet therapy Aspirin + clopidogrel 12/12 Beta-blocker; bisoprolol 12/12 ACEi lifelong; ramipril Statin lifelong; atorvastatin
[General advice] Cardiac rehab Work Driving Diet Exercise Sex Travel
Arrhythmias | Management AF/flutter SVT VT 1st degree/Mobitz type I AV block 2nd/3rd degree AV block
Ectopics
Torsades de pointes
[AF/flutter]
Rate control; >48hrs
Rhythm control; young, new onset, electrolyte imbalance
<48hrs either option
>48hrs rate, must be fully anticoagulated before cardioversion, echo to r/o atrial thrombus
[Rate] Bisoprolol Digoxin; sedentary patients Verapamil OR [Rhythm] Amiodarone (less effective in flutter) DC cardioversion
Anticoagulate CHADSVASC vs. HASBLED
M > 1, offer
F > 2, offer
[SVT] Carotid sinus massage Valsalva manoeuvre Adenosine (Flecainide; structural heart disease)
[VT] Amiodarone IV
DC shock
Heart block
[1st/MT I] Atropine
[2nd/3rd] Pacemaker (Ventricular)
[Ectopics] Observe, if symptomatic amiodarone
[TDP] Magnesium sulfate
(Hypokalaemia)
HF | Aetiology & Investigations
RHF
LHF
RHF; LVF, lung disease, pulmonary stenosis
Systemic peripheral oedema, ascites, raised JVP, pHTN
LHF; Pulmonary oedema, SOB, reduced ET, fatigue, orthopnoea, PND, wheeze, nocturnal cough pinky frothy sputum, weight loss, cachexia
BNP
ECG; may suggest cause, ischaemia, ventricular hypertrophy
CXR; Alveolar oedema, kerley B lines, Cardiomegaly, Dilated upper lobe vessels/diversion, pleural Effusion
Echocardiogram
HF | Management
Acute; pulmonary oedema ‘LMNOP’
Chronic
NYHA I; asymptomatic II; SOB on exertion III; SOB on minor exertion IV; SOB at rest
[Acute] LVF/MR from post-MI/IHD (Oxygen if hypoxic) Morphine Furosemide GTN/isosorbide mononitrate
[Chronic] Furosemide/bumetanide ACEi Beta-blocker (Spironolactone) (Digoxin) (Isosorbide mononitrate)
Salt and fluid restrict 1.5L/day
Daily weights, U&Es
DVT prophylaxis
HTN | Investigations, Aetiology & Target BP
Hypertensive retinopathy
24hr ambulatory BP monitoring (ABPM)
1/52 home BP readings
3x clinic readings
[Aetiology]
Renal disease; GN, vasculitis, PKD
Endocrine; Cushing’s, Conn’s, phaechromocytoma, hyperparathyroidism
Pregnancy, OCP
Consider treating >140/90, calculate CV risk and look for organ damage
Treat all with >160/100
>180/110 treat immediately
Malignant HTN >200/130
(Headache, visual disturbance, papilloedema)
[Target BP] <140/90
Age >80yrs 150/90
DM <130/80
[Hypertensive retinopathy]
- Tortuous arteries with ‘silver wiring’
- AV nipping
- Flame haemorrhages, cotton-wool spots
- Papilloedema
HTN | Management
Malignant HTN
[Caucasian <55yrs]
ACEi/ARB
A+C
A+C+D
[Afro-carribbean, >55yrs]
CCB (nifedipine)
Or thiazide diuretic
[Malignant HTN]
PO atenolol
IV labetalol
Rheumatic Fever | Symptoms & Management
Group A beta-haemolytic streptococcal infection
Complication strep throat or scarlet fever
60% develop chronic rheumatic heart disease
[Symptoms] Criteria
Major; carditis, arthritis, rash, chorea
Minor; fever, raised ESR/CRP, arthralgia, prolonged PR interval, previous rheumatic fever
Tx; IV benzylpenicillin, PO phenoxymethylpenicillin
Aspirin, NSAIDs, prednisolone
Haloperidol, diazepam
Mitral Regurgitation | Clinical features, Aetiology & Investigations
Symptoms
Signs
ECG
CXR
Mitral Stenosis has similar findings
[Aetiology] LV dilatation Rheumatic fever, infective endocarditis Post-MI; papillary/chordae tendinae rupture CTD; Ehlers-Danlos, Marfan's
Symptoms; SOB, palpitations, fatigue
Signs; AF, displaced heaving apex, pansystolic murmur at apex radiating to axilla
ECG; P-mitrale (LA hypertrophy), LVH, AF
CXR; pulmonary oedema, LA/LV enlargement
Aortic Stenosis | Clinical presentation & Management
Triad
Signs
ECG
Elderly person with chest pain, SOBOE, syncope
Triad; angina, syncope, HF
Signs; slow-rising pulse, narrow pulse pressure, heaving non-displaced apex, LV heave, aortic thrill, ejection-systolic murmur at LSE and aortic area radiating to carotids
ECG; LVH, P-mitrale, LBBB, AV block
Tx; valve replacement
Aortic Regurgitation | Clinical features Symptoms Signs ECG CXR
Symptoms; SOBOE, orthopnoea, PND, palpitations, angina, syncope, CCF
Signs; collapsing (water hammer) pulse, wide pulse pressure, displaced apex beat, early diastolic murmur expiration sat forward, carotid pulsation, head nodding with each heartbeat, capillary pulsation in nailbeds
ECG; LVH
CXR; cardiomegaly, pulmonary oedema
Infective endocarditis | Clinical features, Investigations & Management
Signs
Diagnosis
ECG
CXR
Fever + new murmur
Strep. viridans, Staph. aureus (IVDU)
Signs; anaemia, splenomegaly, clubbing, new/changed murmur, systemic emboli
[Diagnosis]
Modified Duke criteria
[Investigations] 3x positive blood cultures at 3 different sites Normochromic normocytic anaemia Urinalysis; microscopic haematuria ECG; AV block Echo; vegetations CT; to look for emboli (spleen, brain)
[Management]
Empirical; ampicillin, flucloxacillin, gentamicin
Staph; flucloxacillin
Strep; benzylpencillin
Pericarditis | Clinical features, Investigation & Management
Aetiology
[Aetiology]
Viruses; Coxsackie virus, EBV, CMV, HIV
Bacteria; TB, pneumonia, Staph, Strep
Systemic autoimmune diseases; vasculitides, IBD, sarcoidosis
[Clinical features] Chest pain worse on inspiration or lying flat, relieved by sitting forward Pericardial friction rub Pericardial effusion Cardiac tamponade; pulsus paradoxus Fever
[Investigations]
ECG; saddle-shaped ST segment, PR depression, widespread ST elevation
Raised troponin
CXR; cardiomegaly, pericardial effusion
Tx; NSAIDs/aspirin + PPI for 1-2/52
Prophylactic colchicine 3/12
Cardiac Tamponade | Clinical features & Management
Beck’s triad; low BP, rising JVP, muffled heart sounds
Tx; pericardiocentesis
Send fluid for culture and cytology