Cardiology Flashcards
What is the diagnosis;
Signs = slow rising pulse, narrow pulse pressure, ESM
aortic stenosis
Where are Osler’s nodes? Are they painful?
finger pulp. yes
Where are Janeway lesions? Are they painful?
palms. no
Differential of systolic murmur
AS, MR, VSD,, aortic sclerosis (musical no radiation), HOCM (decreases with squatting)
Stigmata of endocarditis are…
Osler’s nodes, Janeway lesions, Roth spots,splinter haemorrhages, splenomegaly, haematuria
Causes of aortic stenosis?
degenerative calcification, biscuspid aortic valve(1-2% pop), rheumatic heart disease
Symptoms of severe AS?
syncope, angina, breathlessness
Echo definition of severe AS?
area of valve <1cm2
mean gradient across valve >40mmHg, max gradient across valve >60mmHg
max velocity >4m/s
When should you refer for surgical repair of AS?
severe AS on echo PLUS symptoms or LVEF <50%
What is the diagnosis?
Signs; soft early diastolic murmur loudest at left sternal edge on expiration
AR
Causes of AR?
bicuspid valve, rheumatic heart disease, connective tissue disease (Ehler’s Danlos, Marfans), degenerative aortic valve disease, Ankylosing spondylitis, endocarditis
Rare (syphilis, vasculitis (GCA or Takayasu’s)
What is the genetics of Marfan’s?
Autosomal dominant fibrillin-1 mutation
What is the echo criteria for severe AR?
moderate/severe LV enlargement
central jet width >65% of outflow tract
vena contracta >0.6cm2
Causes of mitral stenosis?
Rheumatic heart disease, calcification, endocarditis
Echo criteria of severe mitral stenosis?
valve area <1cm2
gradient across valve >10mmHg
pulmonary artery pressure >50mmHg