Cardiology Flashcards
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Clinical estimate of left atrial pressure
Pulmonary Capillary Wedge Pressure (PCWP)
Measure of left ventricular preload
Thiazide ^ loop diuretics are contraindicated in patients w/…
TMP/SMX allergy
Total resistance (RT) of a parallel circuit Formula
1/RT= 1/RT1+ 1/RT2+ 1/RT3+ 1/RT4
Drugs to treat chronic HTN in pregnant women ? (4)
Methyldopa➡️ alfa 2 adrenergic receptors
Labetalol
Nifedipine
Hydralazine
Medications assoc w/gynecomastia development (8)
Spironolactone Digoxin Cimetidine OH Ketoconazole Estrogens Omeprazole CCB
Medications that cause lipid abnormalities (2)
Metoprolol
Thiazides
Prazosin
“First dose effect”➡️profound onset of orthostatic hypotension
ACEI adverse effects
Chronic cough
Hyperkalemia
Angioedema
Vagus nerve stimulation
Aortic arch (110-200mmHg)
➡️ CV control center (medulla)
➡️ ⬆️ PNS ^ ⬇️ SNS
Glossopharyngeal nerve stimulation
Carotid sinus (50-180 mmHg)
➡️ cardiovascular control center (medulla)
➡️ ⬆️ PNS^ ⬇️ SNS
Consequences of ⬆️PNS ^ ⬇️SNS (5)
SA node: ⬇️HR
Ventricular myocardium: ⬇️inotropy
Small arteries ^ arterioles: ⬇️ SVR:TPR
veins: ⬇️ ♥️ preload
Vasodilator
Tachycardia w/hypotension
Vasoconstrictor
Bradycardia w/ hypertension
Mobitz type 1
Wenckebach
Causes ?
PR interval progressively lengthens ➡️ non- conducted P wave
BB, CCB, ⬆️vagal tone
Mobitz type 2
Causes ?
PR interval remains unchanged ➡️P wave fails to conduct to the ventricles
Medications, organic lesion in the conduction pathway
B blockers (class II) Adverse effects ? (6)
Impotence Exacerbation COPD ^ asthma ♥️: bradychardia, AV block, HF 🤹♀️: sedation, sleep alterations Mask signs of hypoglycemia 🚫: pheochromocytoma, cocaine toxicity
Vessels w/ the highest resistance ?
Ohm law ?
Arterioles
R=🔼P/Q
Drug traces
Changes in BP will be due to a direct effect
Changes in HR may be due to either a baroreceptor effect or a direct effect