Cardiology Flashcards
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Clinical estimate of left atrial pressure
Pulmonary Capillary Wedge Pressure (PCWP)
Measure of left ventricular preload
Thiazide ^ loop diuretics are contraindicated in patients w/…
TMP/SMX allergy
Total resistance (RT) of a parallel circuit Formula
1/RT= 1/RT1+ 1/RT2+ 1/RT3+ 1/RT4
Drugs to treat chronic HTN in pregnant women ? (4)
Methyldopa➡️ alfa 2 adrenergic receptors
Labetalol
Nifedipine
Hydralazine
Medications assoc w/gynecomastia development (8)
Spironolactone Digoxin Cimetidine OH Ketoconazole Estrogens Omeprazole CCB
Medications that cause lipid abnormalities (2)
Metoprolol
Thiazides
Prazosin
“First dose effect”➡️profound onset of orthostatic hypotension
ACEI adverse effects
Chronic cough
Hyperkalemia
Angioedema
Vagus nerve stimulation
Aortic arch (110-200mmHg)
➡️ CV control center (medulla)
➡️ ⬆️ PNS ^ ⬇️ SNS
Glossopharyngeal nerve stimulation
Carotid sinus (50-180 mmHg)
➡️ cardiovascular control center (medulla)
➡️ ⬆️ PNS^ ⬇️ SNS
Consequences of ⬆️PNS ^ ⬇️SNS (5)
SA node: ⬇️HR
Ventricular myocardium: ⬇️inotropy
Small arteries ^ arterioles: ⬇️ SVR:TPR
veins: ⬇️ ♥️ preload
Vasodilator
Tachycardia w/hypotension
Vasoconstrictor
Bradycardia w/ hypertension
Mobitz type 1
Wenckebach
Causes ?
PR interval progressively lengthens ➡️ non- conducted P wave
BB, CCB, ⬆️vagal tone
Mobitz type 2
Causes ?
PR interval remains unchanged ➡️P wave fails to conduct to the ventricles
Medications, organic lesion in the conduction pathway
B blockers (class II) Adverse effects ? (6)
Impotence Exacerbation COPD ^ asthma ♥️: bradychardia, AV block, HF 🤹♀️: sedation, sleep alterations Mask signs of hypoglycemia 🚫: pheochromocytoma, cocaine toxicity
Vessels w/ the highest resistance ?
Ohm law ?
Arterioles
R=🔼P/Q
Drug traces
Changes in BP will be due to a direct effect
Changes in HR may be due to either a baroreceptor effect or a direct effect
Early cyanosis 😨
5Ts
Truncus arteriosus (1 vessel) Transposition (2 switched vessels) Tricuspid atresia (3=tri) Tetralogy of Fallot (4=tetra) TAPVR (5 letters)
Cardiac function curve for compensated heart failure
Normal resting CO w/⬆️ RAP
Sustained monomorphic ventricular tachycardia hemodinamically tolerated and asymptomatic can be treated initially w/ ?
IV amiodarone, lidocaine, procainamide
First line for stable ventricular tachycardia
Amiodarone
🚫contains iodine= allergies🚫
Classic presentation of an atrial septal defect
Systolic ejection murmur in the left midsternal border, and a wide fixed split of S2
Set of changes seen in anemia
⬇️hematocrit ⬇️tissue PO2 ⬆️arteriolar diameter ⬇️PVR ⬆️CO ^ VR
Pathognomonic sign of AV fistula
⬆️venous oxygen content
Aspects of subendocardial infarction (3)
A state of hypotension can lead to SI
⬆️CK-MB or troponin
ST segment depression or flattening
Patients w/vascular insuficiency to the legs secondary to atherosclerosis would be expected to have
⬇️ankle pulse
⬇️venous O2 content during exercise
⬆️peripheral vascular resistance
⬆️serum lipids
Stenotic bicuspid aortic valve
Midsystolic murmur that radiates to the neck
Aortic valve stenosis
Pulse pressure ?
Diminished
ACEIs are useful to control HTN in patients w/? (3)
Diabetic nephropathy
HF
Hyperuricemia
Drug induced gout
Thiazide diuretics ➡️ HCTZ
Drugs that prolong QT interval
Class IA ^ Class III antiarrhythmics
Drugs contraindicated in long QT sx
Class IA: Quinidine, Procainamide, Disopyramide
Class II: AIDS
Phenothiazines
TCA
Aortic regurgitation (3)
Diastolic murmur
Widened arterial PP
Large stroke volume
Cardiogenic shock (4)
⬇️CO ^ SV
⬆️HR ^ TPR
Fibrates
Activate PPAR alfa
Adverse effects
Gallstones
Muscle toxicity
SVR
formula?
SVR= (MAP - RAP) / CO
HTN proximal to the coarctation develops due to ?
Activation of the RAAS system
⬇️ afferent arteriolar free Ca++ levels
Pulmonary vascular resistance
Formula
PVR= (MPAP - PCWP) / CO
Digoxin adverse effects
Cholinergic: N/V, diarrhea, 🌅🎨, arrhythmias, AV block
⬆️K+
Ohm law
Flow = change in pressure / resistance
Hypertriglyceridemia
Treatment
Fibric acid derivatives
Niacin
Omega 3 fatty-acids
Common side effect assoc w/niacin ?
Facial flushing
Drug that vasodilate ^ ⬇️ release of insulin in response to glucose
Diazoxide
Opens K+ATP channels
Aortic regurgitation
Can occur due to bacterial endocarditis
⬆️PP
Diastolic murmur