Cardiology Flashcards
Stable Angina
Chest discomfort due to myocardial ischemia. Occurs with exacerbation, relieved by rest.
What determines myocardial demand for O2?
HR, SBP, contractility, LV wall stress
Why does subendocardium get ischemic during tachycardia?
Because it receives its blood during diastole, so when tachycardia occurs, diastole preferentially shortens
Most common cause of stable angina
Vasospasm, AS, HOCM, HTN
How to treat asymptomatic patients with moderate framingham risk?
Daily aspirin
Is it recommended to treat women with hormone replacement to prevent heart disease?
No
Is it recommended to test homocysteine?
No
How to screen for CAD?
Dont do it.
How to determine typical vs atypical vs nonanginal cp?
Retrosternal
Relieved by rest/nitro
Exacerbated by activity or stress
1 is nonanginal
2 is atypical
3 is typical
How to use stress testing to diagnose angina?
Patients with low probability don’t require stress test, patients with high probability should be started immediately on medical management. Patients with intermediate pretest probability should receive stress test.
How to choose a stress test?
Patients with baseline changes in EKG shouldn’t get EKG stress, patient’s who can’t exercise need chemical stress.
Dipyridamole for nuclear perfusion, dobutamine for echo
Contraindications for EKG exercise stress
LBBB, ST depressions, WPW, LVH or on digoxin
Contraindications for echo
LVOT obstruction
Wall motion abnormalities
Obese
Contraindications for nuc perfusion
Asthma
hypotension
conduction disease
Goal of exercise or chemical stress
To achieve 80% of max heart rate.
Coronary angiography
Goal standard for patients at high risk or abnormal stress tests. Though patients with abnormal stress tests can be managed medically.
Therapy for chronic stable angina
1) lifestyle modifications
2) Antianginal meds + vascular protective meds
Initial medication regimen for chronic stable angina
Beta blocker, aspirin, long acting nitrate, statin (high intensity for >75, moderate intensity for
How to manage chronic stable angina if symptoms persist on first pass?
Increase B blocker dose, increase nitrate dose, add CCB.
How to manage chronic stable angina if symptoms persist on second pass?
consider ranolazine, refer for angio