Cardiology Flashcards
The physical responses to shock are mediated by:
Catecholamines
Renin, Antidiuretic hormone
Glucagon, Cortisol, and Growth hormone
MC type of distributive shock:
Septic shock
MC etiology of septic shock:
Gram-negative sepsis
MC epidemiology of septic shock:
Extremes of age
Diabetics and immunosuppresed
Recent invasive procedure
Shock tx: Inotropes
increase CO by increasing contractility
dobutamine, dopamine, epinephrine
Shock tx: Chronotropes
alter heart rate
positive - adrenaline; negative - digoxin
Shock tx: Pressors
improve pressure by increasing vascular tone
dopamine, phenylephrine
Orthostatic/Postural Hypotension Defintion:
Drop of 20mmgHG systolic or 10mmHg diastolic between supine and sitting/standing measurements
Orthostatic hypotension:
If increase in pulse of 15bpm or more, what’s the most likely cause?
Depleted circulating blood volume
Orthostatic hypotension:
In no change in pulse, what are possible causes?
Meds, autonomic dz (Parkinson, Shy-Drager), peripheral neuropathies
Orthostatic hypotension:
Diagnostic studies
CBC, BMP, EKG
Tilt test if necessary
Metabolic syndrome is composed of:
Truncal obesity
Hyperinsulinemia and insulin resistance
Hypertryglyceridemia
HTN
Define hypertensive urgency
Systolic > 220 or diastolic > 125.
Persistently elevated…must be lowered within hours
Define hypertensive emergency
Must be lowered within 1 hour to prevent progression of end-organ damage. In the presence of strikingly elevated BP
Define malignant hypertension
Elevated BP associated with papilledema and either encephalopathy or nephropathy.
If untreated, progressive renal failure occurs.