Cardiology Flashcards
What two changes on EKG make you suspicious for MI?
- 2mm ST elevation
- new LBBB (wide, flat QRS)
- these indicate STEMI
pt comes in w/ chest pain.. best 1st test?
EKG
What EKG findings are seen on EKG following MI from 6 hrs to years
T wave inversion
What EKG changes persist indefinitely after MI
Q waves
What three leads show ST elevation in an inferior infarct? What vessel is involved?
I, II, aVF
RCA
What 4 leads are involved in an anterior infarct? Vessel
V1-V4
LAD - is MC place for infarction
What leads have changes in a lateral infarction? vessel?
I, aVL, V4-V6
Circumflex
What should be done after STEMI is dx’d?
- Cath lab
2. thrombolytics if no cath lab and no C/I
If no STEMI is found on EKG and chest pain is present, what test should be done?
Cardiac enzymes
How long after MI can thrombolytics be administered? Contraindications? (5)
less than 6 hours
active bleeding, anticoagulants, any hx of hemorrhagic stroke, recent ischemic stroke, recent closed head trauma
How many times, how often should cardiac enzymes be checked
3x q 8 hrs –> may not be elevated if early enough
Which cardiac enzme elevates 1st?
Myoglobin - peaks in 2 hrs, normal by 24 hrs
When does troponin I rise? peak? normalize?
rises in 3-5 hours
Peaks in 24-48 hours
normal by 7-10 days - poor measure of reinfarction therefore
When does CK-MB rise? peak? When does it normalize?
rises in 4-8 hrs, peak in 24 hrs, normal by 72 hours
If no STEMI but cardiac enzymes are peaked, what is dx?
Non-STEMI MI
What 4 drugs do you treat NSTEMI with?
- Morphine
- O2
- ASA/ clopidogrel
- Beta blocker
Once MI has been confirmed, NSTEMI or STEMI what test needs to be done next and why
Coronary angiography - determines next step in tx
what four things are indications for CABG?
- Left main vessel dz
- 3 vessel dz (or 2 vessel dz + DM)
- Pain despite maximal medical therapy
- Post-infarction angina
*emergent CABG not often done - done after failure of PCI, mechanical complications of acute MI, cardiogenic shock, or life-threatening ventricular arrthymias per step up
What is standard non pharm tx of MI
PCI w/ stenting.
*If meet certain criteria, get CABG
what 6 drugs should a pt w/ MI be discharges home with?
- ASA
- Clopidogrel (if stent placed, use for 9-12 mo)
- Beta blocker
- ACE-I
- Statin
- short acting nitrate
*ASA, BB, ACE-I, Statin all shown to reduce mortality
MCC of death post MI
arrhythmias - esp v-fib
New systolic murmur 5-7 days after MI
Papillary muscle rupture - leads to mitral regurg
- eval w/ echo; decrease preload w/ nitroprusside
Acute severe hypotension occurring w/in 2 weeks after MI
Ventricular free wall rupture –> most commonly 1-4 days after
- need pericardiocentesis, emergent surgical repair
Increase in O2 concentration in RV following MI
Ventricular (Interventricular) septum rupture
- emergent surgery indicated
Persistent ST. Elevation and new systolic MR murmur 1 month after MI
Ventricular wall aneurysm (pseudoaneurysm)