Cardiology Flashcards
2017 ACC/AHA Task force for BP Goals and treatment.
Diagnosis of HTN?
Ambulatory BP monitoring
Home and Office with difference of 19/11 (20/10) mmHg
HTN in children
> = 95th percentile BP for age, gender and height.
Starting age for BP monitor
Age 3 onwards and annually
Secondary work-up for HTN in children
None.
If FmHx of obesity, patient is obese
Causes for secondary HTN in adult
Primary hyperaldosteronism
Get Aldosterone/renin ratio
Now sleep apnea has 30-40 %
Renal artery stenosis
Age <30: Fibromuscular
Age>30: Atherosclerotic disease
ACEi: Renal insufficiency or hyperkalemia
Dx: MRA, CT angio or duplex renal
HTN treatment based on race
Non-Black: Thiazide, CCB, ACEi or ARB
Black: Thiazide, CCB
DM: On ACEi or ARB
Work of thiazide and CCB in African American
Thiazide: Improves HF than ACEi
CCB: Decreases stroke
Give ACEi/ARB for CKD and HF
Side effect of thiazide (renal excretion)
HyperGLUC
G: Hyperglycemia
L: Hyperlipidemia and Increase lithium
U: Hyperuricemia
C: Hypercalcemia
Thiazide side effect (Increase excretion)
Sodium
Potassium
Magnesium
When ACE/ARB is given?
> 18 with CKD
All with DM
No ACEi + ARB together
Decreases progession of microalbuminuria in DM
ACEi side effect?
Cough
Increases lithium toxicity
Angioedema (More in African American)
Reduced BP response to mono ACEi/ARB in African American
CCB types
Dihydropyridine: Amlodipine, Nifedipine, Felodipine and Nicardipine
Nondihydropyridine:
Verapamil > Diltiazem
Dihydropyridine VS Nondihydropyridine
Dihydropyridine:
Vasodilator. No cardiac contractility or AV nodal conduction
Nondihydropyridine:
Less-effective vasodilator. Slow AV conduction. + negative inotropic effect.