Cardio Sketchy Flashcards

1
Q

dihydropyridines

A

act on vascular smooth muscle

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2
Q

non-dihydropyridines

A

act on heart

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3
Q
  • ipine suffix
A

dihydropyridine calcium channel blockers

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4
Q

CCB act by…

A

block voltage-dependent calcium channels of cardiac and smooth muscle

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5
Q

uses for dihydropyridine CCB

A

hypertension, angina (including Prinzmetal), Raynaud phenomenon

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6
Q

uses for non-dihydropyridine CCB

A

hypertension, angina, afib

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7
Q

nimodipine

A

dihydropyridine CCB, used for subarachnoid hemorrhage (prevents vasospasm)

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8
Q

nicardipine

A

dihydropyridine CCB used for hypertensive emergency

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9
Q

clevidipine

A

dihydropyridine CCB used for hypertensive emergency

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10
Q

adverse effects of dihydropyridine CCB

A

peripheral edema, flushing dizziness, gingival hyperplasia

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11
Q

adverse effects of non-dihydropyridine CCB

A

cardiac depression, AV block, constipation, hyperprolacinemia

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12
Q

hydralazine mechanism

A

more cGMP leads to smooth muscle relaxation - dilates arterioles more than veins, decreasing afterload

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13
Q

hydralazine use

A

severe hypertension, HF, usually given with beta blocker to prevent reflex tachycardia

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14
Q

black patients respond best to ……… for hypertension

A

CCB and HTCZ

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