Cardio-Resp-ER-Derm Flashcards
Hyperkalemia Tx
- Ca gluconate IV
- ……..
- ………
Insulin + D50W
NS + Furosemide +|- bicarbonate +|- salbutamol
ACS
Four newer Medications in PCI
- Abciximab
- Bivalirudin
- Tirofiban
- Eptifibatide
GCS
Verbal=5 Scores
2=?
3=?
4=?
2: sounds
3: words
4: confusion
Dyslipidemias
Fibrates CIs
- Hepatic disease
- ……………
- …………….
- Renal disease
- Biliary disease
Intermittent Claudication
Importance of ABI
If <0.4 (severe) Then: Surgery or Pentoxifylline
If 0.4-0.9 Then: RDLE or Pentoxifylline
Intermittent Claudication
Nonpharma tx (1)
Regular Dynamic Leg Exercises (RDLE)
5 times/week for 8 weeks
COPD: Steps in management:
Step 1………….
Step 2…………
- SABD (PRN) = SABA and Ipratropium
- Add LAMA (used regularly)
= Tiotropium Or Glycopyrronuim (new)
Intermittent Claudication
1st line?
2nd line?
- Pentoxifylline (Trial: 4-8w, Max: 24w)
- Ramipril
Stable Angina
3 advices for taking SL NTG in acute phase:
- Max 3 tablets
- ………….
- ………….
- Intervals= 5 minutes
- Sit down to avoid syncope
Chronic Cough: UACS Tx?
(Upper Airway Cough Syndrome)
1st Gen H1 blocker + Decongestant
(UACS= PND: Post Nasal Drip)
CHF
The only safe anti arrhythmic in CHF
Amiodarone
DOC
- Post MI arrhythmia?
- Post MI LV thrombus?
- Beta blocker
- Warfarin
(Warfarin is ok with Plavix but not with Prasugrel or Ticagrelor)
SVTs
Two differences in management of A Flutter vs AFib
- Flutter responds to ablation >95%
- Rate control in Flutter is more difficult
Intermittent Claudication : Pentoxifylline CIs
- Liver disease
- Renal disease
- ………….
- …………
- ………….
- MI
- Bleeding
- PU
Chronic Cough In Pregnancy:
H1 blockers?
Decongestants?
H1: Safe
Dec: Not safe in 1st trimester
SVTs
Cardioversion in A.Flutter or AFib
- Electrical?
- Chemical?
- Poor response
- Better response: Amiodarone IV or Procainamide IV
Dyslipidemias
Monitoring for Niacin:
- LFT
- ……
- ……
- Uric Acid
- FBS
Dyslipidemias
Niacin CIs:
- Severe Gout
- ………
- ………
- Severe Hyperglycemia
- Severe PUD
Near Drowning Tx
ABC, Close monitoring, O2, ………. , ……………
NG suction
+|- SABA or CPAP or BIPAP
Frost Bite Tx
Oxygen, IV fluids, Wound care
………………, …………….., ……………..
Immersion in 40-42 degress water,
Analgesics,
Tetanus Prophylaxis
Insect bite If severe
ABCs + ……………..
Epinephrine 0.1 mg IV
+|- CS or beta2 agonists
Age Related Macular degeneration
Prophylaxis
Smoking Cessation, Controlling HTN
Vit C, Vit E
………….., ……………, ……………
Zinc,
Copper,
Beta Carotene
COPD Management
Indications for CS:
- Inhaled?
- Oral?
- IV or IM?
- ICS: step 4 in chronic management
- Oral: AE of COPD
- IV or IM: No indications!
Prevention of Stroke,
DOC:
- If the cause is Cardiac…..
- If the cause is non Cardiac…….
- Warfarin or newer alternatives
- Plavix
Syncope
DOC for vasovagal
Fludrocortisone
Red Eye
Acute Glaucoma (ER)
Topical beta blocker + Consult/Refer
SVTs
AVRT, AVNRT, FAT
If asymptomatic: No tx
If occasional: …………
If frequent: ………..
Occasional: Pill in the pocket (BBlocker or CCB)
Frequent: BBlocker or CCB
Glaucoma Tx 1st line:
Topical beta blockers: Timolol
And/or ……….
Carbonic Anhydrase Inhibitors: Dorsolamide (Topical)
Dyslipidemias
DOC in Pregnancy or Breastfeeding?
DOC in Children >10 y?
Both:
Resins Like Cholestyramine
Dyslipidemias
Monitoring for Statins
- ………….
- …………
LFT
CPK
Dabigatran (Direct thrombin Inhibitor)
Three Cautions
- Caution in elderly
- …………….
- …………….
- Monitor Plt
- CI in Renal Failure
Glaucoma
Open angle surgeries (2)
Laser Trabeculoplasty
Filtration process surgery
Ophthalmology
Retinal Artery Occlusion
1.Globe massage
2,3,4 ?
Topical beta blocker
IV Mannitol
Mix O2+CO2
Asthma in Children,
Safety:
LRTAs? Omalizumab?
L: Safe
Om: above 12 yo only
Toxicity With Cyanide (Antidote)
Hydroxycobalamine
Chronic Cough
NAEB Tx?
(Non Asthmatic Eosinophilic Bronchitis)
Inhaled ICS
Dyslipidemias
Monitoring for Fibrates
1.CPK
2,3 ?
LFT
Renal
Raynaud’s Phenomenon
DOC in Pregnancy?
DOC in Breastfeeding?
P: Nifedipine XL 30 mg
B: Only nonpharmacologic
GCS
Eye=4 Scores
2=? 3=?
2: Opens in response to pain
3: Opens in response to sound
Asthma: A good control means:
Daily symptoms, less than……
Nighttime symptoms, less than……
SABA use, less than……
D: 4 times/week
N: 1 times/week
S: 4 times/week
VT and VF DOC
- For Electrical Storm (Recurrence of VT or VF)
- For long term prophylaxis of VT
Both: Beta blocker, like Metoprolol
Quinidine SEs
(Cinshonism)
- N/V, Vertigo
- Flushing, Tinnitus
3,4 ?
Lichenoid reaction
Hemolysis
Dyslipidemias
Statins Myopathy:
- If CPK is NL
- If CPK is elevated but <10 times NL
Both: stop statin
- Monitor in 6w
- Monitor in 3w
Prasugrel 3 Limitations:
- Not the best choice if ACS without PCI
- …………….
- …………….
Not in Hx of stroke or TIA
Not in Patients who take Warfarin
Hemorrhagic stroke: SAH
DOC after diagnosis is confirmed
Nimodipine For 3w
Stable Angina
DOC in long term Management
Beta blocker
or Long Acting Nitrates
COPD
Two Criteria in Spirometery that are mandatory for diagnosis
- FEV1 < 80% of predicted value
- FEV1/FVC ratio below 0.7
HTN
Two good indications for CCBs
(Preferably Nifedipine XL)
- African American patients
2 ?
- Isolated systolic BP in elderly
Prevention of Stroke,
DOC: If recurrent…….
Plavix Or Dipyridamole/ASA
Age Related Macular Degeneration
1st line Tx
VEGF Inhibitors Like Bevacizumab
Dyslipidemias
Target LDL
Half of the baseline
Or <2 mmol/L
Asthma in Children
Delivery method:
If < 5 yo ?
If > 5 yo ?
<5 pMDI+Spacer+Mask
>5 DPI or pMDI
Hypercalcemia Tx
Initial?
then?
Initial: NS + Furosemide
Then: +/- Calcitonin +/- Bisphosphonates
Dyslipidemias
Statins CIs:
- Hepatic disease
2,3 ?
- High Alcohol intake
- Pregnancy
Apixaban, Rivaroxaban (Direct Inhibitors of Xa)
3 Cautions
- Caution in elderly
- …………
- …………
Monitor Plt
CI in Renal Failure
Stable Angina
If heart rate is low, which beta blockers are recommended?
Acebutolol or Pindolol
(Intrinsic Sympathetic Activity)
Asthma
3 indications for Ipratropium (Inhaled)
- Acute Exacerbation
- ……. 3……..
- BBlocker induced asthma
- Intolerance to LABA or SABA
CHF
Best beta blocker in CHF (Canadian Guideline)
Carvedilol
COPD
Acute Exacerbation: What Antibiotic?
If simple: Amoxi or Macrolide
If complicated: CoAmoxi or Fluoroquinolone
Dyslipidemias
Monitoring for Cholestyramine:
- LFT
2,3 ?
TG
Electrolytes
SVTs
When do we choose: Rate Control vs Rhythm Control?
If above 65 yo: Rate control
If below 65 yo: first, Rhythm, then Rate
Dyslipidemias Statins Myopathy:
If CPK is elevated >10 times NL
Stop statin
+ Check Renal, Urine Myoglobin now
ACS, PCI/Stent, CABG
Plavix (Clopidogrel)?
Ticagrelor?
Prasugrel?
PCI/Stent: All are good.
ACS: Either Plavix or Ticagrelor (No Prasugrel)
CABG: 5-7 days interval is needed
Age Related Macular degeneration
2nd line Tx
PDT + Verteporfin
COPD Acute Exacerbation:
Main tx
- ………………
- |- Antibiotics
- ………………..
SABD
+|- Oral Prednison
Age Related Macular degeneration
Two SEs Of VEGF Inhibitors
- Endophthalmitis
- Subconjctival hemorrhage
Inhalation Injury Tx
100% O2 (Humidified Oxygen)
+|- hyperbaric O2 (controversial)
COPD
Home Oxygen therapy (15 h/day)
Target PO2 ?
65-80 mm Hg at rest
Renal Colic
Two treatments
Ketorolac + Alpha blockers
SVTs
DOC for Rate control in A.Flutter or AFib
Beta blocker or CCB
HTN
DOC in DM is ACEIs (and avoid ……)
Thiazides (hyperglycemia)
Dyslipidemias
Monitoring for Ezetimibe
1,2 ?
LFT
CPK
COPD
Home Oxygen therapy (15 h/day)
Indications
- SaO2 below 88%
2,3 ?
- PO2 below 55 mm Hg
- PO2 between 55-59 plus: cor polmonale or HCT >56 or Ankle edema
Indications for Anticoagulants
In A.Flutter or AFib
Both: recommended
in Paroxysmal, Persistent, Permanente: all recommended
Based on CHADS2
ACS management STEMI vs NSTEMI
- No rTPA in NSTEMI
- ? 3. ?
- STEMI: Preferably No CCBs
- STEMI: Preferably No IV Nitroglycerin
DVT, PE Prophylaxis
in Major surgeries DOC ?
LMWH (Enoxaparin) For 10-14 days
ACS, STEMI
Relative CIs for Thrombolysis (8)
1,2 Poorly controlled HTN, CVA before 3 months
3,4 Internal bleeding 2-4w, Venous Puncture
5,6 ?
7,8 ?
Pregnancy, Active PU/CPR>10min
Surgery <3w, Current Anticoagulation
GCS MOTOR=6 Scores
2=? 3=? 4=? 5=?
2: decerebrated (extension)
3: decorticated (flexion)
4: localizes pain
5: withdraws with pain
Metabolic Syndrome
Waist above 94 M or 80 F
HDL below 1.03 M or 1.29 F
BP above 130/85
FBS above ……
TG above ……
FBS > 5.6 mmol/L
TG > 1.7 mmol/L
Ischemic Stroke
If you prescribe rtPA: 3 things to monitor
1.BP to be <180/110
2,3 ?
BS to be <12
No ASA, No Heparin
Ischemic Stroke Which one is recommended in general? Heparin/ rtPA (Alteplase) / ASA
H: Not recommended at all !
r: Yes, if between 1-4.5 h
A: ONLY if rTPA is not prescribed, then 160 mg/day
Note: if you prescribe rtPA, do not give ASA for at least 24 hours, then start with 160 mg daily
Stable Angina
CCBs Dyhydropyridines?
DHP= Vascular (Amlopidipine, Nifedipine)
Non DHP= Verapamil, Diltiazem
Asthma: 3 examples of ICS
1.Beclomethasone
2,3 ?
Budenoside
Fluticasone
Glaucoma
Closed angle surgeries (2)
Laser Iridotomy
Surgical Iridectomy
HTN
DOC in Pregnancy (4)
Methyldopa, Hydralazine
………………. , ……………….
Nifedipine XL
Labetalol IV
HTN In general:
DOC if <60 yo
DOC if >60 yo
Below 60: beta blocker
Above 60: Diuretic or ACEI
Syncope
DOC for Orthostatic Intolerance
Fludrocortisone
Or Midodrine (Alpha Agonist)
COPD: Steps in management:
Step 3………….
Step 4…………
Step 5: home Oxygen
- Add LABA (Similar to asthma)
- Switch from LABA to combination of LABA+ICS
Asthma Steps of chronic management
- SABA PRN
- Add ICS regular use
- Add LABA
- …………..
- Oral Prednisone or consider Omalizumab
- Increase ICS dosage
Or Add Montelukast (LTRA)
Or Add Theophylline
Asthma: Theophylline SEs
- Seizures
- Nervousness/Insomnia/Palpitations
- …………………….
N/V Abdominal cramps/Headache
Glaucoma Tx
2nd line (3 groups)
PG Analogues: Latanoprost (topical)
Alpha 2 agonists: Brimonidine (topical)
Cholinergics: Pilocarpine (topical)
ACS Duration of Heparin therapy
STEMI vs NSTEMI
STEMI: 48h
NSTEMI: 2-5 days
ACS, STEMI
Absolute CIs for Thrombolysis (8)
1,2,3 Previous-Known IC Hemorrhage/IC Malignancy/Cerebrovascular lesion
4,5 Within last 3 months: Head or face trauma/Ischemic CVA
6,7,8 ?
6,7,8 Pericarditis/Ao dissection/Active bleeding
Acne
Indication for Glycolic Acid or Azelaic Acid
If intolerant to Retinoids
Acne
Isotretinoin monitoring
1.Beta hCG, Needs contraception
2,3 ?
LFT
Lipid Profile
Acne: Safe or not in Pregnancy?
Oral Retinoids
Topical Retinoids
Spironolactone
Tetracycline/Doxycycline
All are unsafe (All systemic treatments are unsafe during pregnancy)
But: Benzoyl, Glycolic Acid, Topical Erythromycin Are safe
Pregnancy Is SMX/TMP safe?
1st trimester: unsafe
After 32nd week: unsafe
Atopic Dermatitis Nonpharma (4)
- Bathing
- Wet wrap (If expert)
3,4 ?
Emollients like Petrolatum
UVB
Atopic dermatitis DOC
1st line: Topical CS
3 different groups/locations?
Face and folds: Hydrocortisone
Body: Triamcinolone
Palms and soles: Betamethasone
Atopic dermatitis (Eczema)
2nd line tx
Tacrolimus or Pimercolimus
Tacrolimus in Atopic dermatitis
3 rules:
1.Only 2nd line
2,3 ?
Only > 2 yo patients
Only short term
Atopic dermatitis
New Tx for refractory and severe forms
Alitretinoin
Atopic dermatitis
In Pregnancy
Topical CS, Tacrolimus, UVB = safe
But: PUVA, Methotrexate are unsafe
Impetigo
1st line tx
2nd line tx
- Topical Mupirocin or Fusidic Acid For 5 days
- If No response after 48h, Then Cephalexin oral for 7 days
Local Folliculitis
DOC ?
Topical Mupirocin or Fusidic Acid
Folliculitis DOC if disseminated
If hot tub (Pseudomonas) Ciprofloxacin 7-10 d
If Other: Ciprofloxacin or Cephalexin 7-10 days
Furuncle or Carbuncle DOC
Cloxacillin or Cephalexin
Skin infection Associated with edema, erythema And non-clear margins Dx?
Cellulitis (If sharp borders: Erysipelas)
Cellulitis DOC
Mild to moderate: Oral Cephalexin 7-10 days
Severe: Cefazolin IV
Erysipelas DOC
Mild to moderate: Oral Cephalexin 14 days (not 7-10) Severe: Cefazolin IV
Burns
Parkland Formula
4 ml x Wt kg x Percentage of burn = total fluid needed in the first 24 h
(In children add maintenance to Parkland)
Burns and Sunburns
Two best local anesthetics
1……. 2. Lidocaine
Pramoxine
Onychomycosis 1st line:
Oral Terbinafine Monitoring?
LFT
and remember: Terbinafine is a cytochrome inhibitor
Onychomycosis
Duration of tx with Terbinafine
Hands: 6w
Foots: 12w
Onychomycosis
Terbinafine SEs:
- GI, Headache, Rash
- Hepatotoxicity
3,4 ?
Smelling or Tasting sensory problem
Hearing impairment
Onychomycosis
In Pregnancy
No systemic treatment is safe
Only local like Ciclopirox or Efinaconazole
Pruritis Nonpharma (3)
- Hydrating the skin, Mild soaps
2,3 ?
Colloidal Oatmeal
Avoiding excoriation and irritants
Pruritis
DOC in
Dermatographism, Swimmers itch, Mastocytosis
All: H1 blocker
Pruritis
Tx in Miliaria (Heat Rash)
Cooling + Talcum Powder
Pruritis
Local treatments
- Calamine
- ……………..
Menthol
Indications for topical CS in
- Pruritis
- Sunburn
Pruritis: ONLY IF there is an obvious inflammation Sunburn: Not indicated!
Pruritis
Tx In Pregnancy
Either local treatments Or Antihistamines
Lice Nonpharma
- Pets no tx needed
- Close relatives: all need tx
3,4 ?
Mechanical removal Vinegar + towel
Washing clothes with hot water or closed bag
Lice DOC ?
Permethrin 1% for 10 min, then wash
Repeat after 1 week
Scabies DOC ?
Permethrin 5% for 8-14 h, then wash
Repeat after 1 w
Crusted Scabies DOC ?
Both Oral Ivermectin and topical Permethrin 5%
Lice and Scabies
In Pregnancy
DOC: Permethrin (safe)
Sunscreens Two groups
- Physical, like Zinc Oxide
- Organic, like Anthralinates
Psoriasis of Scalp Tx?
Scale removal is important
1,2 ?
Topical Calcipotriol or Betamethasone
Or if severe: Tar based shampoo
Psoriasis in the Face Tx?
Hydrocortisone 1% (Cream)
If severe: Tacrolimus (Topical)
Psoriasis in hand or foot Tx?
Locals: Petrolatum Or Betamethasone Or phototherapy (UVB) with Calcipotriol
Systemic:Acitretin
Psoriasis in body and extremities Tx?
Local: Betamethasone, Calcipotriol, Tar, Tazarotene, Anthraline Or Phototherapy UVB
Psoriasis in fold areas Tx?
Like Psoriasis in the face: Hydrocortisone 1% Or Tacrolimus
Psoriasis
Indications for systemic treatment with Acitretin (3)
- Refractory - Nails - Hands and Feet
Psoriasis In Pregnancy
Safe: Local treatments like CS, Anthraline, Tar. and UVB (best for severe cases in Pregnancy)
Unsafe: MTX, Acitretin, PUVA
Rosacea Ocular subtype Tx?
Topical: ABs + Artificial tear
Systemic: Oral Doxycycline
Rosacea Phymatous subtype Tx?
No topical tx
Systemic: Oral Prednisone or Isotretinoin
Rosacea Erythemato-telangiectatic And Papulopustular subtypes Tx?
Topical: Metronidazole 2-4 w
Systemic: Oral Doxycycline
Rosacea Nonpharma
Avoid: Sunlight, …………… ,Undiluted Liquors, Spicy food, ………….., Hot beverages
Topical CS
Vinegar
Pressure Ulcers Dressing
for superficial wounds (2)
for deep wounds (2)
Sup: Transparent Film, Hydro colloid (Autolytic)
Deep: Xerogel, Hydrogel (Autolytic)
Pressure Ulcers
Two dressings for massive slough
Xerogel
Foam
Tension Pneumothorax:
Needle thoracostomy
2nd ICS mid clavicular line
Then Chest tube in 5th ICS AAL (anterior axillary line)
Open Pneumothorax (Sucking chest wound)
3 way sealed air-tight dressing
Then chest tube
Flail chest
O2 + Judicious Fluid therapy + Pain control
Cholinergic toxidrome
Caused by:
Physostigmine (Anticholinesterase)
Insecticides (Organophosphates)
Tx:
Atropine for Muscarinic effects
Pralidoxime for Nicotinic effects
Herbal Products Black Cohosh
Menopause and PMS
Herbal Products Evening Primrose
Menopause and PMS
Herbal Products Valerian Root
PMS Sedative, Anxyolitic
Herbal Products Ginkgo Biloba
Improves circulation (PAD and Dementia)
Herbal Products Ginseng
Energy enhancer Adjunct for chemo or radiotherapy
Herbal Products Echinacea
Common Cold, Flu Wound treatment
Herbal Products Flaxseed Oil
Laxative Source of Omega 3
Herbal Products Ginger
Nausea, Motion Sickness Dyspepsia