Cardio, Pulm, and Vascular Flashcards
Chest pain questions….
when did pain start?
where is it? what does it feel like? how severe?
does it radiate?
have you felt like this before?
at rest? with exertion? both?
constant? intermittent?
SOB, N/V, diaphoresis, palpitations, fatigue, dizziness, syncope, sense of impending doom
dx tests for chest pain
EKG
CXR
Pulse ox
CBC, CMP, D-dimer, cardiac enzymes, BNP
Echo
if pt has chest pain, what do we do first?
assess vitals
cardiac monitor, IV access, O2
focused hx and physical exam
if pt is stable with chest pain, what do you do
obtain 12 lead EKG and CXR
Administer aspirin if pt is at low risk for aortic dissection
if pt is unstable with chest pain, what do you do?
stabilize ABCs
tx arrhythmias according to ACLS
check for life-threatening chest pain dx: AMI, massive PE, tension pneumothorax, pericardial tamponade
what is this?
pressure, heaviness, tightness, fullness, squeezing in the center or left of the chest precipitated by exertion and relieved by rest
can radiate shoulders, arms, neck, jaw
ANGINA
angina is indicative of what
some type of ischemic event happening in coronaries
anginal equivalents occur in whom
what is it?
women, elderly, diabetic pts
atypical presentation
examples of atypical angina presentation
SOB N/V Diaphoresis Fatigue Dizzy/lightheadedness Weak Palpitations Syncope
symptoms are stable and resolve with rest
stable or unstable angina
stable
increasing severity/frequency/duration OR occurs at risk
stable or unstable angina
unstable
non-occlusive thrombus
ischemia with elevated cardiac enzymes
NSTEMI or STEMI
NSTEMI
occlusive thrombus
transmural infarction
NSTEMI or STEMI
STEMI
CAD risk factors
Male sex
Age over 55 yrs
DM
HLD
HTN
Family hx of CAD
Tobacco
Obesity
History of atherosclerotic disease, prior MI, CVA/TIA, peripheral arterial disease
two things used to calculate MI risk
HEART score
TIMI score
HEART SCORE: what 5 parts of it
- how suspicious is the hx for ACS (0-2)
- EKG changes (0-2)
- Age (0-2)
- # of risk factors (0-2)
- Initial troponin value (0-2)
EKG and CAD - what do we see
resting EKG may be normal
ST-T wave changes: T wave inversions, ST depression or elevation
Cardiac enzymes and CAD
initial troponin then TREND
can’t rule out MI based on single set or just the initial cardiac enzymes – trend!
Stress test and CAD
exercise or pharmacologic
only do if you’re UNSURE if pt is having ACS
do NOT do with STEMI
high sensitivity troponin (hs-cTN assay) is ____ and ____ determinant of myocardial injury
sensitivity and specific
what lab results are indicative of acute MI
acutely elevated hs-cTN over 100
or
values less than 100 ng/L BUT have a 2 hour change of greater than 10 ng/L
chronic elevations of hs-cTn are indicative of what
chronic heart issues
for regular troponins, we trend the value every ___ hours for a total of ___ values
6 hours
3 values
ACS possible + EKG complete
high sensitivity troponin testing at time 0 is LOW (15 or below for men, 10 or below for women)
what do you do next?
you assess if it has been over 6 hours since chest pain/angina onset
if it is –> acute MI ruled out
if it is not – test troponins again at 2 hours
troponin testing at 2 hours
what happens?
delta 3 or less
delta 4-9
3 or less: acute MI ruled out
4-9: tropnin test again at 6 hours
troponin test at 6 hours (since chest pain)
delta < 12 ng/mL from time 0
delta 12+ ng/mL from time 0
less than 12: acute MI ruled out
12+: acute MI present
if at time 0, troponin is high (over 100 ng/mL WITHOUT ESRD, what is it?
MI
if at time 0, high troponin (over 100) + ESRD - what do you do
repeat troponin testing at 2 hours
if chest pain began over 12 hours ago, what does a negative delta mean?
it does not rule out recent MI
Clinical features of acute coronary syndrome - what do you do next? (3 things)
aspirin + analgesia + EKG
EKG shows ST elevation or new LBBB or true posterior MI
STEMI or NSTEMI
STEMI
EKG shows ST depression or T inversion - what do you do?
what does that tell us?
raised troponin
if raised - NSTEMI
if normal - unstable angina
what do we monitor during a stress test?
BP
EKG changes
Echo changes
when do we stop a stress test?
if pt develops chest pain, SOB, ST changes (elev or dep) or has decreased BP or ventricular arrhytmias
when observing a pt for “ACS rule-out”, what do you do
serial cardiac enzymes
stress testing
substernal chest pain lasting 2-5 minutes only with activity and never with rest
stable angina
EKG changes/enzyme changes/exercise stress test with stable angina
NO EKG CHANGES
NO ENZYME ELEVATION
STRESS TEST USUALLY NEG
medical management of stable angina
nitrates - sublingual nitro PRN for chest pain (if no relief call 911) - can take every 5 min for 3 doses in 15 min
beta blockers
+/- calcium channel blockers
antiplatelet medications:
aspirin, plavix or both
variant angina or vasospastic angina
angina 5-15 min usually at rest and often between midnight and early AM
prinzmetal angina
EKG of prinzmetal angina
ST elevation ONLY during chest pain episodes
tx of prinzmetal angina
nitrates + calcium channel blockers
dx prinzmetal angina
coronary angiography
you are about to give a pt nitroglycerin…. what should you ask?
if they recently took sildenafil, vardenafil, tadalafil
WOMEN TAKE THESE TOO
clinical presentation of acute coronary syndrome
chest pain, heaviness, or pressure
SOB
radiates
weakness or fatigue
N/V
diaphoresis
palpitations
dizziness or syncope
when high sensitivity troponin is high (like 200), what do you think?
MI
STEMI initial mgmt
ABCs
Cardiac monitoring (telemetry)
IV access
SL nitro
Aspirin - chewed
+/- beta blocker
anticoag (unfractionated heparin)
Call cardiology
acronym used for initial ACS tx
what has changed?
MONA
Morphine
Oxygen
Nitro
Aspirin
M and O are slowly becoming less used
morphine with STEMI is assoc with what?
increased mortality in STEMI
oxygen with STEMI is assoc with what
increased early myocardial injury and increase infarct size
why must you call cardiology ASAP with a STEMI
because they need to be sent to cath lab ASAP - door to percutaneous coronary intervention is important to improve outcomes
when do you consider fibrinolytics with a STEMI
if PCI is not readily available within 120 minutes
** unless contraindicated! **
gold standard for dx CAD
coronary angiography
PCI interventions (2)
angioplasty and stenting
factors to consider for CABG
number of vessels that are occluded
anatomic complexity of lesions
likelihood to have successful revascularization with PCI
Co-morbidities
initial mgmt for NSTEMI
same as STEMI except:
no thrombolytics
PCI if not contraindicated
can medically manage with heparin continuous infusion and aspirin
PCI contraindications
renal failure
sepsis
unstable pt
do you use MONA with UA/NSTEMI or STEMI or both
BOTH
do you use nitrates with UA/NSTEMI or STEMI or both
both
do you use beta blockers with UA/NSTEMI or STEMI or both
both
do you use anticoagulation with UA/NSTEMI or STEMI or bith?
both
do you use thrombolytics with UA/NSTEMI or STEMI or both
only STEMI and only if PCI is not avail
do you use revascularization with UA/NSTEMI or STEMI or both
later with UA/NSTEMI
early with STEMI
contraindications to nitro
hypotension, right ventricle infarction/inferior MI, recent PDE5 inhibitors (sildenafil)
6 peri-infarction emergencies
Peri-infarction pericarditis***
Acute mitral regurg***
Dressler’s Syndrome ***
Hemorrhage/bleeding
Arrhythmias (bradycardia)
Rupture of LV free wall or intraventricular septum
usually occurs soon after MI (first 2-3 days)
transient
pericardial rub on physical exam
pericardial inflammation +/- effusion
what dx?
PIP - peri-infarctino pericarditis
tx of peri-infarction pericarditis
supportive - self-limited
tylenol
aspiring +/- colchicine
NO NSAIDS
what should be avoided in peri-infarction pericarditis
NSAIDS
pericarditis can happen for many reasons other than post-MI
what are they?
infectious, radiation, post-cardiac injury syndrome, drugs/toxins, metabolic, malignancy, collagen vascular disease, immune-related, idiopathic
how does cardiac tamponade present
chest pain
tachypnea
dyspnea
physical exam of cardiac tamponade
hypotension
JVD/distended neck veins
muffled heart sounds
tachycardia
pericardial rub
what will EKG show on cardiac tamponade
sinus tachy
low voltage
what will CXR show with cardiac tamponade
enlarged cardiac silhouette
what will echo show with cardiac tamponade
effusion
tx of cardiac tamponade
drainage of pericardial effusion: pericardiocentesis
percutaneous or surgical
monitoring of cardiac tamponade
what needs to be done prior to discharge
continuous telemetry
frequent vital signs for 24-48 hours
repeat echo prior to discharge
causes of acute mitral regurg
ischemia to papillary muscle
left ventricle dilation or true aneurysm
papillary muscle or chordal rupture (2-7 days after infarct)
physical exam on acute mitral regurg
hypotension and new murmur
dx of acute mitral regurg
transthoracic or transesophageal
tx of acute mitral regurg
emergency surgery