Cardio Pharmacology Flashcards by Zane freeman | Brainscape

Q

Hydrochlorothiazide

A

thiazide diuretic: blocks early distal tubular Na uptake

risk of hypokalemia

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Q

Furosemide

A

Loop diuretic: blocks loop of Henle Na uptake
risk of hypokalemia
Most effective class

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Q

Spironolactone

A

Aldosterone antagonist - Potassium-sparing Diuretic:

blocks aldosterone stimulated Na uptake in late distal and cortical collecting tubules; hyperkalemia risk

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Q

Eplerenone

A

Aldosterone antagonist - Potassium-sparing Diuretic:

blocks aldosterone stimulated Na uptake in late distal and cortical collecting tubules; hyperkalemia risk

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Q

Amiloride

A

Sodium-channel inhibitor Potassium sparing
Blocks Na uptake in late distal and cortical collecting tubules
Hyperkalemia risk

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Q

Tramterene

A

Sodium-channel inhibitor Potassium sparing
Blocks Na uptake in late distal and cortical collecting tubules
Hyperkalemia risk

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Q

Nifedipine

A

Calcium channel blocker dihydropyridine

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Q

Nicardipine

A

Calcium channel blocker dihydropyridine

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Q

amlodipine

A

Calcium channel blocker dihydropyridine

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Q

Diltiazem

A

Calcium channel blocker

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Q

Verapamil

A

Calcium channel blocker -most heart selective

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Q

Minoxidil

A

Potassium channel opener

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Q

Prozasin

A

Alpha blocker -reduces sympathetic mediated tone

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Q

terazosin

A

Alpha blocker -reduces sympathetic mediated tone

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Q

Doxazosin

A

Alpha blocker -reduces sympathetic mediated tone

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Q

Phentolamine

A

Alpha blocker -reduces sympathetic mediated tone

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Q

Phenoxybenzamine

A

Alpha blocker -reduces sympathetic mediated tone

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Q

Bosentan

A

Blocks ET vasoconstrictor receptors

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Q

Nitrodilators

A

vasodilation via cGMP

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Q

Captopril

A

ACEI

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Q

enalapirl

A

ACEI

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Q

Lisinopril

A

ACEI

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Q

Losartan

A

angiotensin receptor blocker

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Q

valsartan

A

angiotensin receptor blocker

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Q

candesartan

A

angiotensin receptor blocker

Q

Aliskiren

A

Renin inhibitor

Q

Hydralazine

A

Direct-acting vasodilator

Q

Metoprolol

A

Beta blocker

Q

Propranolol

A

beta blocker

Q

Clonidine

A

alpha2 adrenoceptor agonist

Q

guanabenz

A

alpha2 adrenoceptor agonist

Q

guanfacine

A

alpha2 adrenoceptor agonist

Q

alpha-methyldopa

A

alpha2 adrenoceptor agonist

Q

Hexamethonium

A

ganglion blocker

Q

Trimethaphan

A

ganglion blocker

Q

Camsylate

A

ganglion blocker

Q

Antiarrhythmic Class I

A

Sodium Channel Blockers

Q

Antiarrhythmic Class II

A

Beta blockers

Q

Antiarrhythmic Class III

A

Potassium Blockers

Q

Antiarrhythmic Class IV

A

Ca-Channel Blockers

Q

Quinidine, procainamide, disopyramide

A

Antiarrhythmic Class IA

Q

Lidocaine, Tocainide, mexiletine

A

Antiarrhythmic Class IB

Q

Flecainide, Propafenone, Moricizine

A

Antiarrhythmic Class IC

Q

Propanolol, metoprolol, acebutolol, esmolol

A

Antiarrhythmic Class II Beta blockers

Q

Amiodarone

A

Antiarrhythmic Class III

use: supra vent & vent tachy

Q

Dronedarone

A

Antiarrhythmic Class III

Atrial fib and flutter

Q

Bretylium

A

Antiarrhythmic Class III

Life threatening v tach / fib

Q

Sotalol

A

Antiarrhythmic Class III, II

V tach; A fib/flutter

Q

Ibutilide

A

Antiarrhythmic Class III

A fib/flutter

Q

Dofetilide

A

Antiarrhythmic Class III

A fib/flutter

Q

Verapmil, diltiazem

A

Antiarrhythmic Class IV Ca channel blockers

Q

Adenosine

A

Slows SA nodal firing
Dec AV nodal conduction
Uses: rapidly suppress supravent tacky caused by AV nodal reentry

Q

Atropine

A

Blocks excessive vagal tone
Inc Av Nodal conduction & velocity
Uses: Acute AV block reversal

Q

Digoxin

A

Activates Vagus

Uses: A flutter/fib to dec vent rate

Q

Magnesium Salts

A

Enhance opening of Katp channels -> hyperpolarizatoin

Uses: AMI associated arrythmias

Q

Tx for Sinus Tachy

A

II, IV

Q

Tx for A fib/flutter

A

IA, IC, II, III, IV, Digitalis, Adenosine

Q

Tx for AV bloks

A

Atropine

Q

Tx for V tach

A

I, II, III

Q

Tx for Premature V complexes

A

II, IV, Mg salts