Cardio Pharm Indications Flashcards

1
Q

Nifedipine

A

Anti-HTN. Used in conjunction with beta blocker to prevent reflex tachy. Contraindicated post-MI./CHF.

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2
Q

Amlodipine

A

Anti-HTN. Used in conjunction with beta blocker to prevent reflex tachy. Contraindicated post-MI./CHF

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3
Q

Diltiazem

A

Paroxysmal supraventricular dysrhythmias. Not as strong as Verapamil, low side effects. Not effective against HTN.

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4
Q

Verapamil

A

Paroxysmal supraventricular dysrhythmias, angina (decreases demand for O2 and increases coronary blood flow, HTN (reduces SVR).

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5
Q

Furosemide

A

Anti-HTN, CHF.

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6
Q

HCTZ (hydrochorthiazide)

A

First line for uncomplicated Anti-HTN. SEs: sulfa allergy, hypokalemia, insulin resistance, increased TG + LDL.

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7
Q

Losartan

A

Anti-HTN, can be used to treat aortic dilation.

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8
Q

Enlalapril

A

Anti-HTN.

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9
Q

Direct Renin Inhibitors

A

Anti-HTN. Not really used.

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10
Q

Phenoxybenzamine

A

3rd line Anti-HTN. Also used in treatment of BPH.

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11
Q

Prazosin

A

3rd line Anti-HTN. Also used in treatment of BPH.

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12
Q

Doxazosin/Terazosin

A

3rd line Anti-HTN. Also used in treatment of BPH.

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13
Q

Clonidine

A

Anti-HTN, (Watch out for brady), rebound HTN after discontinuation is a big problem.

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14
Q

Spironolactone

A

Anti-HTN.

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15
Q

Hydralazine

A

Used for HTN during preg, pre-ecclampsia, usually in combo w/ beta blockers to prevent reflex SNS. Tox: excessive dilation – flushing, sweating, hypotension, angina, palps, Lupus-like.

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16
Q

Sodium nitroprusside

A

Drug of choice for HTN emergency! Rapid onset, IV. Use beta blockers before withdrawing infusion.

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17
Q

Nitrates

A

Anti-HTN. Anti-angina.

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18
Q

Propranolol

A

Severe HTN

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19
Q

Metoprolol

A

Severe HTN

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20
Q

Carvedilol

A

Systolic dysfunction heart failure.

21
Q

Epinephrine

A

Commonly used after cardiopulmonary bypass or in resuscitations to restart cardiac contractions (rarely used in CHF)

22
Q

Norepinephrine

A

Hypotension, Distributive Shock

23
Q

Dopamine

A

CHF, Hypotension, Bradycardia (med doses), Shock (med and high doses). Side effects: tachy, HTN, vomiting.

24
Q

Dobutamine

A

Can diagnose CAD, simulate exercise.

25
Q

Isoproterenol

A

Post-transplant to drive heart rate and decrease PVR. Can also be used to increase SA node rate if bradycardia is present.

26
Q

Phenylephrine

A

Hypotension, Distributive Shock

27
Q

Milrinone

A

CHF, CAD. Risk of hypotension and shock.

28
Q

Digoxin

A

Atrial arrhythmias (fib), CHF classes II-IV, not great for acute MI (increases cardiac metabolic demand). Drug interactions common - low dose very important. Contra - premature vent contractions, v-tach, AV block, bradycardia, SA node disease w/out pacemaker, uncontrolled hypokalemia, right sided heart failure, hypertrophic myopathy, WPW.

29
Q

Atropine

A

Stops vagal reaction, restores AV conduction in disorders with prolonged AV nodal refractoriness (such as inferior MI or dig toxicity).

30
Q

Acetylcholine

A

Not used clinically.

31
Q

Edrophonium

A

IV bolus, lasts for 30 seconds, used to treat break SVTs due to AV nodal reentry or AV bypass tract. Used to diagnose SVTs.

32
Q

Physostigmine

A

No active clinical use.

33
Q

Neostigmine

A

No active clinical use.

34
Q

Anything-astatin

A

Hypercholesterolemia. 1st line therapy for LDL reduction, very effective. Can cause rhabdomyolysis, myalgia, myopathy.

35
Q

Fibrates

A

HyperTGemia to prevent pancreatitis. Adjunct to statins.

36
Q

Niacin

A

Hyperlipidemia.

37
Q

Cholesterol absorption inhibitor

A

Used with statins or with statin-intolerant patients.

38
Q

Bile acid sequestrant

A

Add to statin therapy, or with statin-intolerant patients.

39
Q

Aspirin

A

NSTEMI, STEMI

40
Q

Clopidogrel

A

NSTEMI, STEMI (bleeding risk)

41
Q

Glycoprotein Iib/IIIa inhibitor

A

NSTEMI, STEMI (bleeding risk)

42
Q

t-PA, streptokinase, urokinase

A

STEMI (bleeding risk)

43
Q

Heparin

A

NSTEMI, STEMI (bleeding risk)

44
Q

Procainamide/Quinidine

A

V-tach, A-fib, AV Reentry. May cause Torsade in pts with long QT (if so treat with isoproterenol to increase HR, decrease QT)

45
Q

Lidocaine

A

V-tach, A-fib, AV Reentry. May cause Torsade in pts with long QT (if so treat with isoproterenol to increase HR, decrease QT)

46
Q

Flecainide

A

V-tach, A-fib, AV Reentry. May cause Torsade in pts with long QT (if so treat with isoproterenol to increase HR, decrease QT)

47
Q

Amiodarone

A

V-tach, A-fib, AV Reentry. May cause Torsade in pts with long QT (if so treat with isoproterenol to increase HR, decrease QT)

48
Q

Sotalol

A

V-tach, A-fib, AV Reentry. May cause Torsade in pts with long QT (if so treat with isoproterenol to increase HR, decrease QT)

49
Q

Adenosine

A

Reentry arrhythmias that require AV node: AVNRT, AVRT, WPW. Contra: 2nd, 3rd degree heart block, sick sinus, long QT, severe hypotension