Cardio pharm Flashcards
what antiarrhythmic
inc AP duration
inc (ERP) effective refractory period
inc QT interval (blcoking some K channels)
Class IA
Quinidine
Procainamide
Disopyramide
“Double Quarter Pounder
which Class 1 drugs
dec/shorten AP duration
perferentailly affect ischemic and purkinje tissue
Class 1B
Lidocaine,
Mexiletine
Tocainide
indications for class IB antiarrhythmics?
Lidocaine, Mexiletine
post MI!!!!!!!!!!!!!!!
Digi induced arrhythmias
what antiarrythmic class
Prolongs ERP in AV nodes and bypass tract
no effect on ERP in urkinje or Ventricles.
what are they used for?
class 1C
Flecainide, Propafenone.
these are hardly used anymore bc SE
indications: SVTs, including (A-fib) ,
last resort regractory VT
when are Class 1C CI?
Post -MI
what class of drugs
Inc APD
inc ERP
inc QT interval
Class III
“AIDS”
Amiodarone
Ibutilide
Dofetilide
Sotalol
what antiarrhythmic causes
dec conduction velocity
INC ERP
INC PR interval (period in which inpulse is delayed through AV node)
Class IV ca channel blockers
the prolong phase 4 depolarization
dec slope of phase 0 in pace maker cells