Cardio pharm Flashcards
what is considered elevated BP
systolic 120-129 AND diastolic <80
what is normal BP
<120/80
what are the two stages of Hypertension
Stage 1: S-130-139 or D: 80-89
Stage 2: S >140 or D >90
What are the ACC/AHA goals
decrease systolic pressure <130
Tx for Elevated BP
3-6 months
First tier HTN medications
ACEI/ARB
DHP CCB
Thiazide-like diuretics
What does Aldosterone do in the urine
Na reabsorption and K excretion as well as H2O retention
ACEI mechanism
inhibit conversion of ANg I to II
blocks ACE
and decrease afterload
endings of ACEI and the most common drug here
“pril”
Lasonopril
endings for ARBs and the main drug here
“sartan”
Losartan
ACEI/ARBS main adverse drug effects
Dry COUGH and Angioedema (most comon on first week, AfroAmerican ppl at riskk here)
Hypotention (1st dose)
HYPERKALEMIA
Contraindication of ACEI/ARBS
Pregnancy X
renal artery stenosis
Ccalcium channel blockers DHP ending and the main drug
dipines
-Amlodipine
CCB non-DHP are better compared to CCB-DHP for the heart, yes or no ?
who are they ?
*hint this is what dad takes
yes b/c it works on the heart specifically
VERAPIMIL and Diltiazem
what is the ending of a alpa 1 blocker that is second line for HTN?
sozin
Doxazosin , Prazosn
alpha 1 blocker (2nd line HTN) MOA
-antagonize alpha 1 receptor on vasculature of SM
-vasodoalate peripheral sm
-DECREASE afterload
alpha 1 blocker (2nd line HTN) ADR
postural hypotension (drops when you stand up)
Dizziness