Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Cardiology > Cardio Literature > Flashcards

Cardio Literature Flashcards

1
Q

What are the main uses of cTnI?

A

HSA in dogs with pericardial effusion
DCM
Myocarditis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the main uses of BNP?

A

Differentitate cardio vs resp
HCM
Onset of CHF (and respond to tx)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the only biomarker NOT affected by renal disease?

A

NCX-1 = Sodium Calcium exchanger

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the prognosis with rupture of LA?

A

POOR

All died within 1 month

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the prognosis with chordae rupture?

A

Most recover!

MST 369 days :)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Can TnI be used to dx incipient DCM?

A

YES >0.22

Even with no echo or holter changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What can be combined with NT-ptoBNT to increased accuracy of diagnosing occult DCM?

A

Holter Monitoring

Dec survival if >50 VPC or >900 NT proBNP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What did the PROTECT study show in DCM dogs?

A

Delayed onset of CHF and sudden death in dobies with preclinical DCM (MST 718 vs 441) with pimobendan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What type of DCM do cockers get?

A

Taurine def

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What type of DCM do boxers get?

A

Carnitine def

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What can be used on a radiographic to differentiate dyspnea from cardiac vs noncardiac in cats?

A

• Vertebral Heart Scale system may be useful to differentiate cardiac from noncardiac cause of resp distress in cats
○ VHS >8: Screening with heart disease (VHS >9.3 very specific for heart dz, if 8-9.3 unknown could be heart or resp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What increased the likelihood of identifying bacteria in dogs with endocarditits?

A

• Performing single sample 16S RNA identified 39% with bacteria compared to 33% with blood culture
○ No study animal had different bacteria identified (but only 2 dogs had both tests +)
○ Combining PCR and blood culture = identified 61% - Suggesting that this increases the likelihood of identification of bacteria in blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What could be a biomarker of cardiac fibrosis in dogs with chronic cardiac disease?

A

cTnI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Did strenuous activity affect cTnI? From sled dogs

A

No!
○ Strenuous exercise (sled dogs) did NOT result in CTnI concentrations above RR (but did increase slightly)
§ After two days CRP did not increased above RR

Suggesting that moderate exercise should not affect the cTnI or CRP in normal dogs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which biomarker is increased with anemia and IMHA?

A

cTnI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which biomarker can be used to identify incipient DCM dogs?

A

cTnI

cTnI >.22 ng/ml suggestive of underlying cardiomyopathy (even in clinically normal dogs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which biomarker can be performed on pleural fluid in cats to determine cardiac vs non-cardiac cause of the fluid?

A

○ NTproBNP can be measured on pleural fluid in cats to distinguish cardiac cause (higher level) from non-cardiac cause of pleural effusion

Pleural fluid and plasma NTproBNP correlated in cats (higher in cardiac cases)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What can pimobendan result in in cats with systolic anterior motion of MV?

A

Hypotension

19
Q

What can be monitored at home in MVD and DCM dogs that is predictive of resolution of CHF?

A

RR :)

20
Q

Is heart rate reliable in cats to diagnose CHF?

A

NO!!

21
Q

Can cats have no heart murmur with CHF?

A

YES!!

22
Q

Is RDW associated with presence of heart failure or MVD?

A

NO

23
Q

Is cough associated with CHF in dogs?

A

No

24
Q

What is the QUEST study in heart failure?

A

Pimobendan increased time before intensification of CHF in cats compared to benazepril

25
Q

Was spironolactone helpful in MVD dogs?

A

Yes!
• Dogs with moderate to severe MVD the addition of spironolactone to conventional tx decreased risk of reach primary endpoint (cardiac related death, euthanasia, or worsening) - Reduced by 69%

26
Q

What could be used as biomarker on examination to monitor dogs with MVD?

A

• Dogs with MVD has increased HR and decreased heart rate variability (assessed by vasovagal tone index) over a year before death (greatest changes in doges dying/euthanized from cardiac dz)
○ HR and VVTI could be biomarkers!

27
Q

What has been associated with pathogenesis of activation of valvular interstital cells in dogs with MVD?

A

Serotonin (5HT)

28
Q

What is the MST for HCM?

A

1276 days

29
Q

What is associated with a poor prognosis in HCM?

A

LAE

30
Q

What has been demonstrated with the platelets of HCM cats?

A

• P-selectin and sPECAM were increased in HCM cat platelets indicating platelet activation (may be biomarkers of increased platelet activation in HCM cats)
○ True for resting platelets and stimulated platelets (ADP)
○ Correlated with heart murmur and end-systolic cavity obliteration

31
Q

What odd side effect can you get with amlodipine?

A

Generalized edema

32
Q

How did stem cells therapy work in DCM dogs?

A

• Retrograde venous delivery of tyrosine mutant adeno-associated virus 2 stromal derived factor 1 adipose derived mesenchymal stem cells = SAFE, BUT no survival advantage in dogs with occult DCM

33
Q

Is hypertension in Shelties correlated with proteinuria?

A

No

34
Q

What resulted in a better outcome in cats with DCM?

A

Pimobendan
• Cats with non-taurine responsive DCM did better with pimobendan (all given lasix, taurine, and ACEi, some on digoxin): Pimo group was 4X long MST (49 days compared to non pimo group 12 days)
○ Hypo thermia and FS

35
Q

What is true regarding hypertensive encephalopathy?

A

prognosis is good for resolution of neuro deficits with normalization of blood pressure (vasgenic edema on MRI)

36
Q

Is there a role of hypoT4 in DCM?

A

NO!
• NO role of hypoT4 in etiology or progression of DCM in Dobermans
○ Tx of hypoT4 did NOT improve clinical outcome (dogs still progressed)
○ Dogs with DCM were 2.26 fold higher risk of also being affected with hypoT4

37
Q

What breed can have coronary artery anomalies?

A

English Bulldogs with PS (CAREFUL with ballooning)

38
Q

What can be used in Golden puppies to predict SAS?

A

-Effective orifice area indexed to body surface area

• In Golden puppies: LVOT V max >2.3 m/s and EOAi

39
Q

What deletion has been found in ARVC?

A

Striatin deletion

40
Q

What pathway in ARVC dogs is inhibited and related to growth and differentiation of adiocytes?

A

Wnt pathway

41
Q

What is a common finding in Chaga’s disease?

A

Bradyarrhythmias that need pacemaker placement

42
Q

What should you do if you have a healthy cat with a heart murmur?

A

Need to ECHO

53% have underlying heart disease

43
Q

What dose spontaneous echocardiogenic contrast likely represent?

A

Hyperfibrinogenemia (unknown risk of TED)

Cardiology (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions