Cardio I Flashcards
Name 9 functions of the cardiovascular system.
- Bringing nutrients into the body (from intestine to liver)
- Bringing fuel to cells (glucose from liver to brain)
- Bringing O2 to cells from lungs
- Removal of waste products
- Circulation of hormones
- Circulation of immune cells and antibodies
- Regulation of pH
- H2O balance
- Thermoregulation
Which organ makes the most use of the cardiovascular system for fuel transport? Explain why.
The brain, because it does not have its own stores of glucose, which it uses for energy. This also means that it’s the first organ affected in the case of cardiac arrest.
Explain why the cardiovascular system is needed for thermoregulation during exercise and during extreme heat/cold events.
When you exercise, your body produces heat. Muscle is not very efficient - only 15% of the energy expended produces work. The other 80% becomes heat (hyperthermia) that the cardiovascular system allows for the loss of. The body must ensure that it loses heat fast enough to avoid the body’s temperature rising too high. On the flipside, if it’s too cold, if the body temperature falls too low, you will die.
Give an example of an organism that doesn’t require a cardiovascular system and explain why.
Amoeba. They are about 0.3 mm in length, and do not need a vascular system or a heart. The oxygen in the water can just diffuse directly into their bodies, and they take in bacteria with pseudopodia.
A single cardiac muscle cell is called a […]
cardiomyocyte
[…]% of the cells in the heart are contractile cardiomyocytes
99%
On average, what is the ratio of capillaries to cardiac myocytes?
1:1
Is the ratio of capillaries to cardiomyocytes relatively high or low? Explain the function of this.
It is the highest of any other organ. Because it works all the time, so the oxygen consumption is very high. A dense network of capillaries is therefore needed to produce big concentration gradients.
What is diffusion?
The spontaneous movement of particles caused by random thermal motion.
Diffusion is dictated by […] law.
Fick’s
What is the formula for fick’s law?
Flow = D x concentration gradient x A
Where D is diffusion coefficient and A is cross-sectional area of membrane
State Fick’s law with the formula for concentration gradient integrated. State each variable.
Flow = D x ((Cout - Cin)/d) x A
Where D is diffusion coefficient
A is cross-sectional area
Cout is concentration outside of membrane (ISF)
Cin is concentration inside cell
d is thickness of membrane (distance travelled)
What is flux? State the formula.
Flux = flow/area = D x ((Cout - Cin)/d)
How does the diffusion rate of O2 compare to CO2?
CO2 diffuses 20 times more easily than oxygen in water.
Transportation of glucose from the liver to the brain is an example of what cardiovascular system function?
Bringing fuel to cells