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Theraputics > CARDIO Formulary (cad & hf) > Flashcards

CARDIO Formulary (cad & hf) Flashcards

1
Q

Non-DHP CCB

A

diltiazem, verapamil

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2
Q

Diltiazem brand name

A

Cardizem, Tiazac

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3
Q

Diltiazem doses

A

IR- 80-120 mg TID
XR- 180-360mg QD

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4
Q

Diltiazem AEs

A

Reduced myocardial contractility (V>D), AV/SA nodal conduction disturbances, bradycardia, AV block, Hypotension, HA, flushing, Constipation (V>D)

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5
Q

Diltiazem Monitoring

A

goal hr, constipation, av nodal disturbances

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6
Q

verapamil brand

A

Verelen, Calan, Isoptin

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7
Q

verapamil dosing

A

ir- 60-90mg TID or QID
sr- 240mg qd

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8
Q

verapamil AEs

A

Reduced myocardial contractility (V>D), AV/SA nodal conduction disturbances, bradycardia, AV block, Hypotension, HA, flushing, Constipation (V>D)

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9
Q

verapamil monitoring

A

goal hr, constipation, av nodal disturbances

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10
Q

DHP CCB

A

amlodipine, felodipine ER, nifedipine XL
nifedipine

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11
Q

Amlodipine brand

A

Norvasc

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12
Q

Amlodipine doses

A

5-10 mg qd

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13
Q

amlodipine AEs

A

Hypotension, flushing, HA, dizziness, PERIPHERAL
EDEMA (arteriole vasodilation), reduce myocardial
contractility, reflex adrenergic activation

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14
Q

amlodipine monitoring

A

blood pressure, HR, edema

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15
Q

felodipine ER brand

A

Plendil

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16
Q

felodipine ER doses

A

5-10mg qd

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17
Q

felodipine ER AEs

A

Hypotension, flushing, HA, dizziness, PERIPHERAL
EDEMA (arteriole vasodilation), reduce myocardial
contractility, reflex adrenergic activation

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18
Q

felodipine ER monitoring

A

blood pressure, HR, edema

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19
Q

nifedipine XL
nifedipine brand

A

Procardia-XL

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20
Q

nifedipine XL
nifedipine doses

A

30-60 mg qd
10-20mg tid

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21
Q

nifedipine XL
nifedipine AEs

A

Hypotension, flushing, HA, dizziness, PERIPHERAL
EDEMA (arteriole vasodilation), reduced myocardial
contractility, reflex adrenergic activation

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22
Q

nifedipine XL
nifedipine monitoring

A

blood pressure, HR, edema

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23
Q

Nitrates

A

isosorbide mononitrate
isosorbide dinitrate
nitroglycerin
(SL, patch, IV)

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24
Q

nitroglycerin
(SL, patch, IV) brands

A

Nitrostat (SL tab), Nitrolingual (spray),
Nitro-Dur (patch), Nitro-Bid (ung)

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25
Q

nitroglycerin
(SL, patch, IV) doses

A

300-600 mcg SL tab acutely
2.5-26 mg BID to QID chronic
0.4 mg/spray acutely
5-20 mcg/min IV acutely
0.2-0.8 mg/hr patch (on 12h, off 12h)

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26
Q

nitroglycerin
(SL, patch, IV) AEs

A

Headache (throbbing, pulsating), hypotension,
lightheadedness, dizziness, facial flushing,
reflex tachycardia

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27
Q

nitroglycerin
(SL, patch, IV) monitoring

A

Blood pressure (hypotension),
HR (tachycardia), diary that lists # of NG
doses used per week, how many episodes
of chest pain encountered, do not use with PDEI, use APAP for HA

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28
Q

isosorbide mononitrate brand

A

Imdur

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29
Q

isosorbide mononitrate doses

A

ir- 10-20mg bid
er- 30-240mg qd

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30
Q

isosorbide mononitrate AEs

A

Headache (throbbing, pulsating), hypotension,
lightheadedness, dizziness, facial flushing,
reflex tachycardia

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31
Q

isosorbide mononitrate monitoring

A

Blood pressure (hypotension),
HR (tachycardia), diary that lists # of NG
doses used per week, how many episodes
of chest pain encountered, do not use with PDEI, use APAP for HA

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32
Q

isosorbide dinitrate brand

A

isordil

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33
Q

isosorbide dinitrate doses

A

ir- 5-40mg bid to tid
er/sr- 40-80mg qd

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34
Q

isosorbide dinitrate AEs

A

Headache (throbbing, pulsating), hypotension,
lightheadedness, dizziness, facial flushing,
reflex tachycardia

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35
Q

isosorbide dinitrate monitoring

A

Blood pressure (hypotension),
HR (tachycardia), diary that lists # of NG
doses used per week, how many episodes
of chest pain encountered, do not use with PDEI, use APAP for HA

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36
Q

b1 selective beta blockers

A

atenolol, bisprolol, metroprolol succinate, nebivolol

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37
Q

b1 selective and non-selective beta blockers AEs

A

Bradycardia, sinus arrest, AV block, reduced LVEF
(b/c decreased contractility), fatigue, depression,
nightmares, sexual dysfunction, intensify insulin-
induced hypoglycemia, peripheral vascular
complication, B-blocker withdrawal syndrome
(causes angina), bronchoconstriction (non-
selective only)

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38
Q

atenolol brand

A

tenormin

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39
Q

atenolol doses

A

50-100mg qd

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40
Q

b1 selective and non-selective beta blockers monitoring

A

Goal HR (rest: 50-60 bpm, exercise: <100 or
75% of anginal HR), painful episode journal
and NTG use, caution asthmatics

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41
Q

bisoprolol brand

A

zebeta

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42
Q

bisprolol doses

A

initial: 1.25mg qd
target: 10mg qd

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43
Q

metropolol succinate brand

A

troprol xl

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44
Q

metoprolol succinate doses

A

initial: 12.5mg- 25mg qd
target: 200mg qd

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45
Q

nebivolol brand

A

bystolic

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46
Q

nebivolol doses

A

5-40mg qd

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47
Q

non-selective beta blocker

A

propranolol

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48
Q

propranolol brand

A

hemangeol, inderal

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49
Q

propranolol dose

A

80-160mg qd

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50
Q

tPA mimic

A

alteplase, reteplase, tenecteplaase

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51
Q

tPA mimics AEs

A

bleeding

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52
Q

tPA mimics monitoring

A

Bleeding, angioedema, hx of stroke, peptic
ulcer, severe HTN, or trauma

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53
Q

alteplase brand

A

activase

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54
Q

altplase doses

A

15mg bolus, 0.75mg/kg over 30 min, 0.5mg/kg over 60 min

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55
Q

reteplase brand

A

retevase

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56
Q

reteplase dose

A

10u bolus, 10u boluse after 30 min

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57
Q

tenecteplase brand

A

TNKase

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58
Q

tenecteplase doses

A

30mg if <60kg, 35mg if 60-70kg, 40mg if 70-80kg, 45mg if 80-90, 50mg if >90kg

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59
Q

LMWH

A

enoxaparin

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60
Q

enoxaparin brand

A

lovenox

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61
Q

enoxaparin dose

A

prophylaxis -30mg sc q12h or 40mg sc qd
treatment- 1mg/kg q12h or 1.5mg/kg qd
0.5mg/kg iv bolus

62
Q

enoxaparin AEs

A

bleeding, injection site rash, fever

63
Q

enoxaparin monitoring

A

CBC with platelet, SCr, fecal occult blood,
anti Xa levels

64
Q

Factor Xa inhibitor

A

fondaparinux

65
Q

fondaparinux brand

A

arixtra

66
Q

fondaparinux dose

A

2.5mg sc qdaily

67
Q

fondaparinux AEs

A

bleeding

68
Q

fondaparinux Monitoring

A

anti Xa levels, scr

69
Q

direct thrombin inhibitor

A

bivalirudin

70
Q

bivalirudin brand

A

angiomax

71
Q

bivalirudin dose

A

0.7mg/kg, then 1.75mg/kg/hr

72
Q

bivalirudin AEs

A

hypotension, nausea, bleeding, muscle ache, HA

73
Q

bivalirudin monitoring

A

activated clotting time, signs of bleeding

74
Q

thiazides

A

hydrochlorothiazide

75
Q

hydrochlorothiazide brand

A

microzide, esidrix, hydrodiuril

76
Q

hydrochlorothiazide dose

A

initial: 25mg/day
max: 50mg/day

77
Q

hydrochlorothiazide AEs

A

Hypokalemia, hypomagnesemia, hypercalcemia,
hyperuricemia, hyperglycemia, hyperlipidemia,
sexual dysfunction, Li toxicity

78
Q

hydrochlorothiazide monitoring

A

CI with sulfa allergy or anuria, K+, Mg2+,
Ca2+, uric acid, blood glucose, lipids

79
Q

Class V antiarrhythmic

A

digoxin

80
Q

digoxin brand

A

lanoxin, digitalis, digox

81
Q

digoxin dose

A

0.125mg-0.25mg daily

82
Q

digoxin AEs

A

nausea, vomiting, dizziness, HA, thrombocytopenia

83
Q

digoxin monitoring

A

Serum digoxin, K+, Ca2+, Mg2+, SCr, signs of
digoxin toxicity

84
Q

ARN/ARB

A

sacubitril/valstartan

85
Q

sacubitril/valsartan brand

A

entresto

86
Q

sacubitril/valsartan AEs

A

Hypotension, hyperkalemia, dizziness, angioedema

87
Q

sacubitril/valsartan monitoring

A

scr, K+, angioedema

88
Q

anticoagulant

A

heparin

89
Q

heparin brand

A

hemochron, hep-lock

90
Q

heparin dose

A

80u/kg iv bolus, then 18u/kg/hr infusion

91
Q

heparin AEs

A

bleeding, thrombocytopenia, osteoporosis, hypersensitivity

92
Q

heparin monitoring

A

aPTT, signs of bleeding

93
Q

late iNa blocker

A

ranolazide

94
Q

ranolazide brand

A

ranexa

95
Q

ranolazide dose

A

500-1000mg bid

96
Q

ranolazide AEs

A

constipation, nasuea, dizziness, ha, dose-related increase in QT-interval

97
Q

ranolazide monitoring

A

Don’t use with strong 3A4 inhibitors or
inducers or drugs that also prolong QT interval,
watch renal function

98
Q

alpha 1 antagonist + nonselective beta blockers

A

labetalol, carvedilol

99
Q

alpha 1 anatagonist + non selective beta blockers AEs

A

Orthostatic hypotension, tingling of skin, nausea,
dizziness, fatigue, see B-blockers

100
Q

alpha 1 antagonist + non selective beta blockers monitoring

A

bp, hr

101
Q

labetalol brand

A

normodyne, trandate

102
Q

labetalol dose

A

200-400mg bid

103
Q

carvedilol brand

A

coreg

104
Q

carvedilol dose

A

initial: 3.125mg bid or 10mg qd
target: 25mg bid or 80mg qd

105
Q

Decrease TG

A

omega-3 fatty acid

106
Q

omega-3 fatty acid brand

A

lovaza

107
Q

omega-3 fatty acid dose

A

4g qd

108
Q

omega-3 fatty acid AEs

A

burping, indigestion, bad taste in mouth, smelly breath

109
Q

omega-3 fatty acid monitoring

A

TG, LDL-C, liver function tests

110
Q

HCN inhibitor

A

ivabradine

111
Q

ivabradine brand

A

corlanor, procoralan

112
Q

ivabradine dose

A

2.5-5mg bid, adjust q2w based on hr
max- 7.5bid

113
Q

ivabradine AEs

A

afib, bradyarrhythmia

114
Q

vassopressor

A

dobutamine, dopamine

114
Q

ivabradine monitoring

A

HR, bradyarrhythmia

115
Q

dobutamine brand

A

dobutrex

116
Q

dobutamine AEs

A

angina, tachyarrhythmia, HA, dyspena

117
Q

Dobutamine monitoring

A

ECG, HR, BO, pulmonary wedge pressure, CO, K+

118
Q

dopamine brand

A

inotropin, dopastat

119
Q

dopamine dose

A

2-50mcg/kg/min

120
Q

dopamine AEs

A

chest pain, HTN, palpitations, tachycardia, HA, Anxiety, dyspnea

121
Q

dopamine monitoring

A

ECG, BP, HR, SCr, CVP, caution extravasation

122
Q

COX-1 inhibitor

A

aspirin

123
Q

aspirin dose

A

75-162mg qd

124
Q

aspirin AEs

A

gi bleeding, intercrannial bleeds, hypersensitivity, major bleeding

125
Q

aspirin monitoring

A

bleeding, gi ulcers

126
Q

furosemide dosing HF

A

initial- 20-40mg QD or BID
usual- 20-60mg QD or BID

127
Q

torsemide dosing HF

A

initial- 10-20mg QD
usual- 10-80mg QD

128
Q

spironolactone dosing HF

A

crcl> 50
- initial: 12.5 - 25mg QD
-maintenance: 25mg QD
crcl<50
-initial: 12.5 QD or every other day
-maintenance: 12.5-25 mg QD

129
Q

eplerenone dosing HF

A

crcl>50
- initial: 25mg QD
-target: 50mg QD
crcl< 50
-initial: 25mg every other day
-maintenance: 25mg QD

130
Q

sacubitril/valsartan dosing HF

A

high dose- 49/51mg BID; max - 97/103 mg BID
low dose- 24/26mg BID

131
Q

hydrochlorothiazide brands HF

A

esidrix, hydrodiuril

132
Q

hydrochlorothiazide dosing HF

A

initial- 25mg QD
max- 100m QD

133
Q

enalapril dosing HF

A

initial- 2.5-5mg
target- 10mg bid

134
Q

captopril dosing HF

A

initial- 6.25-12.5mg TID
target- 50mg TID

135
Q

lisinopril dosing HF

A

initial- 2.5-5mg QD
target- 20-40mg QD

136
Q

quinapril dosing HF

A

initial- 5-10mg BID
target- 20-40md BID

137
Q

ramipril dosing HF

A

initial- 1.25-2.5mg QD
target- 5mg BID or 10mg QD

138
Q

fosinopril dosing HF

A

initial- 5-10mg QD
target- 40mg QD

139
Q

losartan dosing HF

A

initial- 25-50mg
target- 150mg

140
Q

valsartan dosing HF

A

initial- 20-40mg BID
target- 160mg BID

141
Q

candesartan dosing HF

A

initial- 4mg QD
target- 32mg QD

142
Q

bisoprolol dosing HF

A

initial- 1.25mg QD
target - 10mg QD

143
Q

carvedilol dosing HF

A

initial- 3.125mg BID
target- 25-50mg BID
CR
- initial: 10mg QD
-target: 80mg QD

144
Q

metoprolol tartrate dosing HF

A

initial-12.5-25mg QD
target- 200mg QD

145
Q

SGLT2 inhibitors HF

A

dapagliflozin and empagliflozin 10mg QD

146
Q

hydralazine dosing HF

A

initial- 25mg TID/QD
target-75mg TID
max- 100mg TID

147
Q

isdn dosing HF

A

initial- 20mg TID/QD
target- 40mg TID
max- 80mg TID

148
Q

ivabradine dosing HF

A

2.5mg BID, adjust q2 weeks based on HR

149
Q

digoxin dosing HF

A

0.125-0.25mg QD

Theraputics (4 decks)

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