Cardio drugs - easier Flashcards
Which antiarrhythmics prolong the QT interval?
Class IA and Class III
Which antiarrhythmics cause constipation?
quinidine (may cause constipation due to antimuscarinic effects or diarrhea due to alpha effects)
amiodarone
Ca2+ channel blockers (verapamil, diltiazem)
Which antiarrhythmics are contraindicated in COPD and asthma?
β-blockers (class II) (Adenosine may cause bronchospasm)
Which antiarrhythmics may mask signs of hypoglycemia?
β-blockers (class II)
Which antiarrhythmic drug may exacerbate vasospasm in Prinzmetal angina?
propranolol
Which antiarrhythmic is contraindicated in cocaine users?
β-blockers
For overdose of which antiarrhythmic would you give glucagon?
β-blockers
Which class is flecainide in?
IC
Which class is propafenone in?
IC
Which class is mexiletine in?
IB
Which class is procainamide in?
IA
Which class is ibutilide in?
III
Which class is sotalol in?
III
Which class is dofetilide in?
III
Which class is carvedilol in?
II
Which class are K+ channel blockers?
III
Describe the curve of IC drugs
slope of phase 0 is very decreased
Describe the curve of IB drugs
slope of phase 0 is slightly decreased and AP duration is decreased
Describe the curve of IA drugs
slope of phase 0 is moderately decreased and AP duration is prolonged
Describe the curve of class III drugs
normal phase 0, very prolonged AP
Which drugs work on nodal cells rather than nerve fiber conduction?
Class II, IV
Caffeine and theophylline block the effects of which antiarrhythmic drug?
Adenosine
Which drug is used for diagnosing/abolishing paroxysmal supraventricular tachycardia?
Adenosine
Which antiarrhythmic drug has a duration of action of 15 seconds? Which has a T1/2 of 80 days?
15 seconds: adenosine
80 days: amiodarone