Cardio Drugs

Question 1

Classifications of Anti-Hypertensive Drugs

Answer 1

1. vasodilators
2. agents affecting adrenergic function
3. agents affecting renin angiotensin system (RAS)
4. Diuretics

Question 2

Drug names of Direct Arterial Vasodilators

Answer 2

Hydralazine (lupus like syndrome)
Minoxidil (hair growth)
Diazoxide
Nitroprusside
Fenoldopam

Question 3

Drug names of Calcium Channel Blockers

Answer 3

Dihydropyridines:
 - Nifedipine
 - Amlodipine
Non-dihydropyridines:
 - Diltiazem
 - Verapamil (constipation)

Question 4

Drug names of alpha1/2 blockers

Answer 4

Phenoxybenzamine

Phentolamine

Question 5

Drug names of just alpha 1 blockers

Answer 5

Prazosin
Terazosin
Doxazosin

Question 6

What is major factor of consideration when prescribing alpha1 blockers

Answer 6

•First Dose Effect
– orthostatic hypotension (esp Prazosin)
– transient dizziness, faintness, palpitations, syncope within 1 to 3 hours of 1st dose
– reflex tachycardia
– first dose at bedtime to minimize effect

Question 7

Drug names of Beta1 blockers

Answer 7

Metoprolol
Atenolol

*these are cardiac selective

Question 8

Drug names of non-specific Beta blockers

Answer 8

B1/B2 = Propanolol

B1/B2/a1 = Labetalol

Question 9

Drug names of Central Alpha 2 agonists

Answer 9

Clonidine (anti-cholinergic SE)
Guanabenz
a-Methyldopa (causes hepatitis)

Question 10

Drug names of Neuronal and Ganglionic Blockers

Answer 10

Guanethidine
Guanadrel
Reserpine
Trimethaphan

Question 11

Drug names of Diuretics

Answer 11

HCTZ
Furosemide
Amiloride

Question 12

Drug names of Aldosterone Antagonists

Answer 12

Spironolactone

Eplerenone

Question 13

Drugs names of RAS inhibitors

• ACE Inhibitors
• Angiotensin II Receptor Blockers (ARBs)
• Direct Renin inhibitor

Answer 13

ACE:
- Captopril
- Lisinopril
- Enalopril
ARB:
- Losartan
Direct Renin Inhib:
- Aliskeren