Cardio board correlates Flashcards
Pulse pressure
Sys -Dias
Mean Arterial Pressure
MAP = (2/3 of Dias) + (1/3 of sys)
Central venous pressure
CVP =~Right Atrial Pressure
Pressure in the vena cava
0 mmHg
Pressure in the large arteries
Pressure in systemic capillaries
17 mmHg
Pressure in pulmonary capillaries
7 mmHg
P wave
atrial depolarization
QRS complex
ventricular depolarization
T wave
Ventricular repolarization
Master pacemaker of the heart
SA node
Cause of SA node depolarization
Calcium influx
Most metabolic organ
Brain
Most efficient extractor of oxygen from blood
Heart
Mobitz I
Prolongation of PR interval before dropped QRS complex
Mobitz II
no prolongation of PR interval
Inc in venous return will increase the HR
Bainbridge reflex
Inc in venous return will inc stroke volume
Frank-Starling mechanism
AV block that causes fainting d/t the initially suppressed state of the Purkinje fibers
Stokes-Adams syndrome
HPN, irreg respiration & bradycardia d/t activation of the CNS ischemic response and baroreceptor reflex in pts w/ inc ICP
Cushing reflex
Orthostatic hypotension
Fall in SBP > 20 mmHg
DBP > 10 mmHg
in supine to upright w/in 3 mins
Resistant HPN
BP >140/90 despite taking >3 antiHPN agents, including a diuretic
Ohm’s law
BP = CO x TPR CO = HR x SV
Failure to inc HR during exercise
Chronotropic incompetence
Unstable angina
Angina w/ at least one of the ff:
1) Occurs w/ minimal exertion at rest, lasting >10 min
2) Severe and of new onset (w/in prior 4-6 wks)
3) Has crescendo pattern
Abdominojugular reflux
Pressure on RUQ for 10s
(+): rise >3 cm in JVP for at least 15s after release
Holosystolic murmur of tricuspid regurg becomes LOUDER during INSPIRATION and diminishes during expiration
Abdominojugular reflux
Murmur of aortic stenosis is transmitted to APEX
Gallavardin effect
Weak and LATE peripheral pulse in aortic stenosis
Pulsus parvus et TARDUS
Occurs in mitral valve disease and sever pulmo HPN
High-pitched, diastolic, decrescendo BLOWING murmur along LEFT sternal border
Graham Steell murmur
Rapidly rising “water hammer” pulse
Collapses suddenly as arterial pressure falls rapidly during late systole and diastole
Corrigan’s pulse
Capillary pulsations
Alternate flushing and paling of the skin at the root of the nail while pressure is applied to the tip of the nail
Quincke’s pulse
Booming “pistol-shot” spund heard over the femoral arteries
Traube’s sign
To-and-fro murmur audible over the femoral artery
Duroziez sign
Apical pulse is reduced and may retract in systole (constrictive pericarditis)
Broadbent’s sign
Patch of dullness and inc fremitus below the left scapula d/t pericardial effusion
Ewart’s sign
Rise or lack of fall of the JVP w/ inspiration d/t constrictive pericarditis
Kussmaul’s sign
Fall in sys BP by >10 mmHg with inspiration assoc w/ cardiac tamponade
Pulsus paradoxus
Calf pain on dorsiflexion of the foot, suggestive of DVT
Homan’s sign
CRUNCHING noise synchronous w/ the heart beat in pneumomediastinum
Hamman’s sign
Dx triad of WPW
Wide QRS complex
Short PR interval
Delta wave: slurring of initial part of the QRS complex
Triad of chronic renal failure in ECG
Peaked T waves (hyperK)
Long QT d/t ST segment lengthening (HypoCa)
LVH (systemic HPN)
Beck’s triad of cardiac tamponade
Hypotension
Muffled heart sounds
Distended neck veins w/ prominent x-descent but an absent y-descent
Plaques that have cause fatal thromboses
Thin fibrous caps
Relatively large lipid cores
High content of macrophages
Major determinants of myocardial O2 demand
HR
Myocardial contractility
Myocardial wall tension
Triad of Buerger’s disease
Claudication of the affected extremity
Raynaud’s phenomenon
Migratory superficial vein thrombophlebitis
Virchow’s triad
Stasis
Vascular damage
Hypercoagulability
Class of anti-arrhythmic and MOA of the ff:
Quinidine
Procainamide
Disopyramide
Class IA: prolong action potential by binding to activated Na channels
Clinical use of Class IA antiarrhythmics
A. fib
A. flutter
V. tach
Class and MOA of the ff antiarrhythmics:
Lidocaine
Tocainide
Mexiletine
IB: shortens AP by binding to both activated and inactivated Na channels
Clinical uses of IB anti-arrhythmics
Post-ischemic arrhythmia
V. fib
V. tach
Class and MOA of the ff anti-arrhythmics:
Flecainide
Encainide
Propafenone
IC: no effect on AP but binds to activated Na channels
Uses of IC anti-arrhythmics
Sever refractory ventricular arrhythmia
Class and MOA of the ff anti-arrhythmics: Sotalol Ibutilide Bretylium Amiodarone
III: Bind to K channels; prolongs AP
Clinical uses of Class III anti-arrhythmics
Atrial and ventricular arrhythmias
Class and MOA of the ff anti-arrhythmics:
Verapamil
Diltiazem
IV: Blocks voltage-gated Ca channels
Clinical uses of Class IV anti-arrhythmics
Supraventricular tachy
Rate reduction in pts w/ atrial fibrillation