Cardio

Question 1

HMG-CoA reductase inhibitor (statins)

Answer 1

• Use: decr LDL
• SE: myositis, hepatitis
• potent for lowering LDL

Question 2

Cholesterol absorption inhibitor (ezetimibe)

Answer 2

-Use: decr LDL

Question 3

Fibrates (gemfibrozil)

Answer 3

• Use: decr triglycerids, slightly incr HDL

- SE: augment myositis w statins

Question 4

Nicotinic acid (niacin)

Answer 4

• Use: decr triglyceride, incr HDL
• SE: hepatitis, flushing
• use aspirin to decr flushing

Question 5

Bile acid-binding resins

Answer 5

• Use: decr LDL

- SE: bloating, cramping, GI