Cardio Flashcards
Three types cardiomyopathy + which is most common?
dilated** (MC)
hypertrophic
restrictive
Dilated cardiomyopathy:
common cause
prognosis
symptoms same as
CAD w/ prior MI (ischemic damage)
death w/in 5 years
CHF symptoms
Treatment of Dilated Cardiomyopathy
-Dig
-Diuretics
-Vasodilators
+/- anticoagulation
HCOM:
- inheritance pattern
- type of dysfunction
- AD
- diastolic dysfunction
Murmur assc with HCOM?
Worse with?
Loud S4 + systolic ejection murmur @ LLSB
worse with Valsalva, standing
Initial drug to treat symptomatic HCOM
BBers
Surgical treatment of HCOM
myomectomy
Restrictive Cardiomyopathy:
-dysfunction type
- impaired diastolic filling
- systolic function variable
Causes of Restrictive Cardiomyopathy
SASH CC sarcoid amyloid scleroderma hemochromatosis chemo carcinoid ....or idiopathic
Echo findings in restrictive cardiomyopathy
large atria, normal ventricles
bright myocardium in amyloidosis
Definitive diagnosis of restrictive cardiomyopathy
biopsy
Hemochromatosis treatment
sarcoid treatment
hemochromatosis- phlebotomy, deferoxamine
sarcoid- steroids
Dig is contraindicated in what type of restrictive cardiomyopathy?
Needed when?
amyloid
used in other cases if systolic dysfunction is present
Three viral causes myocarditis
HHV6
parvo
coxsackie
Bacterial causes myocarditis (3)
GAS
Lyme
mycoplasma
Medication that may cause myocarditis
sulfonamides
Acute pericarditis most common causes
post viral/ coxsackie
Complications of acute pericarditis
effusion
tamponade
How is pericarditis distinguished from MI? (4)
pleuritic pain (assc with breathing)
pain relieved when sitting up
friction rub
DIFFUSE STE, PRD
Specific EKG finding in pericarditis
PRD
Treatment of pericarditis
NSAIDs
colchicine
Fibrous scarring of the pericardium is termed ____.
Dysfunction type is ____.
constrictive pericarditis
diastolic dysfunction
Constrictive pericarditis auscultation:
EKG:
pericardial knock
low voltage QRS, T waves
Pericardial effusion clinical findings
dull heart sounds
soft PMI
Pericardial effusion CXR findings
enlarged heart without pulm vascular congestion
When is pericardiocentesis indicated?
evidence of cardiac tamponade
What causes cardiac tamponade?
dysfunction type?
high rate pericardial fluid accumulation, volume irrelevant
diastolic dysfxn
Aside from penetration, what conditions lead to tamponade?
post MI
pericarditis (neoplastic, uremic esp.)
(3) clinical features of tamponade
high JVP
narrow pulse pressure
pulsus paradoxus
Define pulsus paradoxus
decreased arterial pressure (more than 10) during inspiration
Best diagnosis of tamponade
echo
EKG finding in tamponade
electrical alternans
Mitral Stenosis:
- MCC
- cardiac cascade assc with MS
- RF
- elevated LAP –> pulm congestion & a fib
Unique symptoms of MS (4)
- hemoptysis
- purple/pink cheeks
- emboli
- hoarseness (LAE –> RLN compression)
EKG finding assc with MS
broad based notched P waves
Murmur assc with MS + severity determinant
S2 –> opening snap –> loud S1
decreased distance between S2 –> OS= increased severity
Treatment of MS
- Diuretics
- BBers
- warfarin
(symptomatic only)
Aortic Stenosis:
cardiac cascade assc
AS –> LVH –> mitral regurg
Three causes of AS
- senile calcification (70+)
- bicuspid valve
- RHD
Murmur assc with AS
crescendo-decrescendo systolic murmur at RSIS
radiates to carotids
Pulse abnormality assc with AS
parvus et tardus
diminished pulses, delayed carotid upstrokes
Treatment of AS
valve replacement
Cause of UE differential BP
supravalvular aortic stenosis
Cause of systolic anterior motion of mitral valve
HCOM
Cause of Sudden Cardiac Arrest in post-infarct patients
re-entrant ventricular arrhythmia
4 Labs in initial evaluation of HTN
- U/A
- chem panel
- lipids
- EKG
Aortic Insufficiency (Regurg) PE findings
head bobbing
uvula bobbing
pistol shot sound over femoral arteries
Murmur and pulse assc with AI
widened pulse pressure
diastolic decrescendo murmur
Treatment of acute AR
replace valve emergently
Medical treatment of chronic AR
diuretics
dig
vasodilators
reduce afterload, limit salt
Three acute causes of MR
endocarditis
papillary muscle rupture
chordae tendineae rupture
MR:
murmur
common arrhythmia
holosystolic murmur at apex
afib
MR treatment
vasodilation + anticoagulation with afib
How common is TR?
70% normal adults have asx TR
TR is secondary to ____.
RVD
as in heart failure, inferior MI
Tricuspid endocarditis cause
IVDA
MVP histology
myxomatous degeneration
Murmur assc with MVP (+2 maneuvers that increase)
midsystolic click , increased by Valsalva/ standing
Treatment of MVP
generally benign, none indicated
MC valvular abnormality assc with RF
mitral stenosis
Diagnostic requirements RF
2 major or 1 major/2 minor
Major criteria RF
JONES
- joints (polyarthritis)
- cadiac involvement
- nodules
- erythema marginatum
- Sydenham chorea
How is ARF treated?
NSAIDs, monitor with CRP
px is penicillin/e-ymcin in GAS pharyngitis
New heart murmur + unexplained fever =
endocarditis
Acute endocarditis:
bug
valve type
staph, normal valve
Subactue endocarditis:
bug
valve type
strep viridans, enterococcus
diseased valve
Culture negative endocarditis bugs
HACEK haemophilus actinobacillus cardiobacterium eikenella kingella
Most common bug assc with post op endocarditis
staph epi
MC valve + bug assc with IVDA endocarditis
tricuspid, staph
Gold standard endocarditis dx
transesophageal echo
Major criteria endocarditis
bacteremia , TEE diagnosed endocardial involvement OR new valve regurg
Treatment duration of endocarditis
4-6 weeks
vanc + AG until bug isolated
Marantic endocarditis cause + makeup of vegetations
cancer
fibrin + platelets
Treatment for Libman Sacks Endocarditis
anticoagulate
Most common type ASD + age at onset
ostium secundum (central portion of septum) age at onset- 40
ASD murmur + Dx
wide, fixed split S2 - dx with TEE
Murmur assc with VSD
blowing, holosystolic
Coarctation of the Aorta is assc with what syndrome?
Turners
ECG findings in coarctation
LVH –> Left Axis Deviation
PDA is assc with what syndrome?
Congenital rubella
Murmur assc with PDA
continuous machine like murmur
TOF defects
IHOP interventricular septal defect hypertrophy of RIGHT ventricle (Right is right answer) overlying aorta pulmonic stenosis
Murmur assc with TOF
LUSB crescendo decrescendo
EKG + CXR findings in TOF
RAD
Boot shaped heart
Amiodarone complications + most common
pneumonitis **MC thyroid tox liver tox corneal deposits skin discoloration (blue --> gray) neuropathy
Mechanical failure assc with MI at:
day 1
days 3-5
weeks 1-2
day 1: RVF
days 3-5: papillary/ septal defect
weeks 1-2 free wall rupture
Definition of HTN emergency?
urgency?
- BP above 220/120
- end organ damage
(urgency= BP above 220/120 w/o end organ damage)
Effect of severe HTN on: brain pulm cardio kidneys
brain- AMS, ICH
pulm- pulm edema
cardiac- angina/MI/CHF/dissection
hematuria, renal failure
PRES- define
Posterior reversible encephalopathy syndrome
PREs- radiographic finding
posterior cerebral white matter edema
Treatment of HTN emergency
hydralazine nitroprusside esmolol labetolol (IV)
Ilicit drugs that cause HTN emergency
LSD
meth
cocaine
(+alcohol withdraw)
Management of serve H/A and HTN?
antiHTN agent –> CT –> LP
Goal reduction of BP in HTN emergency? urgency?
emergency-reduce by 25% in 1-2 hours w/ IV meds
urgency- reduce BP over 24 hours with oral meds
Aortic Dissection:
causes
- longstanding HTN
- cocaine
- trauma
- CT disorder
- bicuspid aortic valve, coarctation
- third trimester pregnancy
Two types of aortic dissection:
Type A: ascending aorta involved, retrograde flow **surgical** Type B: distal to subclavian artery
Location of pain in dissection
Type A: anterior chest
Type B: intrascapular
Pulse, BP, auscultation abnormalities in AD
pulse asymmetric between limbs
BP usually ^^ but may be low
aortic regurg
CXR finding in AD
mediastinal widening
Preferred tests in dx of AD
CT
TEE
Medical treatment of AD
- BBer
- IV nitroprusside until BP under 120
Location of most AAAs + MC age/ sex
between renal arteries and iliac bifurcation
males over 50
Signs of impending AAA rupture
flank/umbilical ecchymoses
Triad of AAA rupture
hypotension
palpable pulsatile abdominal mass
abdominal pain
Dx test of choice for AAA
U/S
What AAAs are surgical?
greater than 5 cm or symptomatic
Peripheral Vascular Disease is aka?
Chronic Arterial Insufficiency
Signs of PVD in lower extremities
- color change
- ulcers
- muscle atrophy
- thickened toenails
- hair loss
PVD most important risk factor
smoking
MC site of stenosis in PVD
superficial femoral artery
Symptoms of PVD
intermittent claudication/ rest pain (severe, poor prognosis)
Arteries related to calf claudication? hip?
calf- femoral, popliteal
hip- aortoiliac
Diagnosis of PVD
- ankle to brachial index
- pulse volume
- arteriography (gold standard)
Define ankle to brachial index (ABI)
systolic BP in ankle: arm
normal 0.9-1.3
claudication occurs at 0.7
Medical treatment PVD
reduce risk factors
symptom control (ASA)
cilostazol (PDEi)
Acute arterial occlusion- most common location + common causes
femoral artery
- afib
- aneurysms
- atheromatous plaque
Treatment of acute arterial occlusion
- IV heparin
- surgical embolectomy
Cholesterol Embolization Syndrome most common cause + symptoms
triggered by procedure
small areas of tissue ischemia
Treatment of cholesterol embolization syndrome
supportive, no anticoagulation
Mycotic aneurysm: cause and location
infection, aortic wall
Luetic heart is caused by ____.,
Location? Sex? Age?
syphilis
aorta (ascending aneurysm)
male: 40s-50s
Treatment of luetic heart
IV penicillin + surgery
Virchows triad
endothelial injury
venous stasis
hypercoagulability
Why are many DVT patients asx?
superficial vein remains patent
What is Homans sign?
calf pain on ankle dorsiflexion (DVT sign) I
DVT : Dx
d-dimer, Doppler U/S (sensitive not specific)
Phlegmasia cerulea dolens:
define + cause
severe leg edema = caused by extreme DVT
Treatment of DVT
Heparin to PTT at 1.5-2x aPTT, INR 2-3.