Cardio Flashcards
What does the femoral artery become?
popliteal artery
Which artery is most injured by posterior dislocation of the knee?
popliteal artery
what does the popliteal artery branch into?
posterior tibial artery and anterior tibial artery
what causes aortic stenosis in younger patients
calcification of the valves
what causes a harsh crescendo-decresendo midsystolic murmur that radiates to the neck
aortic stenosis
what enzyme is useful to determine if there is heart muscle damage?
CK-MB
what is CK-MB assocaited with
brain damage
what is CK-MM associated with
skeletal muscle damage
What happens during high intensity static exercise (weight lifting)
blood vessels are compressed increasing vascular resitance and decreasing blood flow. Leads to increased cardiac output –> increased MAP.
What happens during dynamic endurance exercise?
vascular resistance decreases and blood flow increases due to metabolic vasodilation of the arterioles. Capillary filtration rate can increase downstream, which increases lymph flow from the muscle.
Which beta 1 blocker can cause varying degrees of heart block?
Atenolol
adverse effects of Beta blockers
- impotence - CV (bradycardia, AV block, HF) - CNS (seizures, sedation) - dyslipidemia - asthma/COPD
Beta 1 selective blockers
-acebutolol -atenolol -betaxolol -esmolol -metoprolol (go from A to M, B1 w/first half alphabet)
What 2 diseases cause increased pulse pressure?
aortic regurgitation Arteriosclerosis
What 2 dieases cause decreased pulse pressure?
aortic stenosis mitral stenosis
What disease increases diastolic pressure?
mitral stenosis
What diseases decrease diastolic pressure?
aortic regurgitation PDA
Which class of drugs is recommended for treatment of hypertension in diabetic and/or heart failure patients?
ACE inhibitors (enalapril, lisinopril, captopril)
What can cause an arteriovenous fistuala?
formation of a psuedoaneurysm that can erode through the wall
What does an arteriovenous fistula do to the return and cardiac output curves?
- shifts the venous return curve to the right and rotates it upward
- increased cardiac output, but the curve doesn’t change - arterial pressure is increased but TPR is decreased
What are two classic risk factors for the development of a pulmonary embolus?
- hip fracture
- prolonged bed rest
Presents 4-8 weeks post MI and results from a large anterior or anteriorseptal defect. Complications include arrythmias, thromboembolism, and congestive heart failure.
Ventricular aneurysm
What beta blockers have intrisinc sympathomimetic activity and SHOULD NOT be used in patients with angina?
- Pindolol
- Acebutolol
They increase the HR and don’t reduce the myocardial oxygen demand.
What is the most common cause of death within 24-48 hours following an MI?
arrythmia
What is associated with weak peripheral pulses?
aortic stenosis
What is being measured when a pulmonary wedge cathetere is
- A - inflated
- B- deflated
- A = inflated is measuring left atrial pressure
- B=deflated is measuring pulmonary artery pressure (25/8)
What can cause chest pain that is NOT relieved by nitroglycerin and shows NO elevated troponin or CK-MB. However, there may be ST depression.
Acute coronary syndrome caused by thrombus of a coronary artery
What pathological changes are seen with stable angina?
- loss of myocytes with fibrosis
- vacuolization of the myocytes in the subendocardium
What is the physiology behind coarctation of the aorta?
- Coarctation lowers renal artery pressure –> wall stress is reduced –> less calcium released –> initates renin release & RAAS system active
What are the 4 physiological things that occur with cardiogenic shock?
- decreased stroke volume
- decreased cardiac output
- increased systemic vascular resistance
- increased cardiac preload
What is characterize by lack of P waves and fluctuating R-R intervals?
- Atrial fibrillation
how is atrial fibrillation treated in a person who is over 75 years w/history of atherosclerotic disease?
- use heparin for first few days
- use warfarin for long term
What is the cause of endocardial cushion defects and what disease are they associated with?
- cause = failure of neural crest cells to migrate
- associated with Down’s syndrome
What drug has aldosterone blocking effects in collecting tubule and can cause gynecomastia?
- spironolactone