Cardio Flashcards
What does the left circumflex artery supply
Left ventricular wall
What does the marginal branch supply
Right ventricle
What does the posterior descending artery supply
Posterior and inferior left ventricle
Calculate map
1/3 systolic + 2/3 diastolic
Name the three layers of arteries and veins
Intima media adventitia
What is the aorta is blood supply
Vasa vasorum
Inotropy
Myocardial contraction
Lusitropy
Myocardial relaxion
Chronotropy
SA node firing
Dromotropy
AV mode conduction velocity
Me neurotransmitter of the sympathetic nervous system
Norepinephrine
Where is renin released from
The kidneys
Three reasons why am renin is released
Low blood pressure
low sodium
norepinephrine stimulation
Where is angiotensinogen made
Liver
Four things that angiotensin II does
Smooth muscle construction
water resorption
ADH release
aldosterone release
Purpose of aldosterone
Triggers renal sodium and water resorption and potassium excretion
Recommended daily allowance of sodium per day
1500 mg per day
How much do most antihypertensive meds drop blood pressure
7-13 / 7-8
Mechanism of action of diuretics
Inhibits the NaCl pump on the distal convoluted tubule leading to increased sodium excretion and water excretion
Class of HCTZ
Diuretic
Side effect of HCTZ
Hypokalemia
Mechanism of action of potassium sparing diuretics
Block sodium channels in the distal nephron
Midamore
Amiloride
Potassium sparing diuretics
Dyreniun
Triamterene
Potassium sparing diuretics
Side effect of potassium sparing diuretics
Hyperkalemia
Class of antihypertensives used and CHF
Loop diuretics
Mechanism of action of Loop diuretics
Blocks sodium potassium chloride transporter in the loop of Henley. Decreased sodium reabsorption and thus less watery absorption
Ladin
Furosemide
Loop diuretic
Side effect of Loop diuretics
Dehydration leaving to Renal failure
Demedex
Torsemide
Loop diuretic
Mechanism of action of ace inhibitors
Decrease angiotensin II production
increase bradykinin levels
decrease sympathetic activity
Prinvil
Lisinopril
ACEi
First line antihypertensive for patients with renal disease
Ace inhibitors
Side effect of lisinopril
Angioedema and cough
Vasotec
Enalapril
ACEi
Diovan
Valsartan
ARB
Cozaar
Losartan
ARB
Mechanism of action of aldosterone antagonist
Aldosterone receptor antagonist
increase potassium
decrease sodium reabsorption and thus less water reabsorption
Aldactone
Spironolactone
Aldosterone antagonist
Side effect of Aldactone
Decreases testosterone and increases estradiol leaving to gynecomastia impotence and menstrual abnormalities
Mechanism of action of beta blockers
Competitively inhibits beta-1 receptors
decreases heart rate and contractility
lowers cardiac output
Lopressor
Metoprolol
Beta blocker
Contraindication of beta blockers
Asthma and COPD
Trandate
Labetolol
Beta blocker
Which beta blocker also has alpha-1 inhibition
Labetalol
Alpha blocker mechanism of action
Alpha-1 receptors blocker
Cardua
Doxazosin
Alpha blocker
Hytrin
Terazosin
Alpha blocker
Mechanism of action of sympatholytic agents
Alpha-2 receptors agonists decreased resistance by decreasing sympathetic outflow and depleting norepinephrine
Catapress
Clonidine
Alpha-2 receptors agonist
Side effects of Catapress
Rebound hypertension sexual dysfunction
Which antihypertensive helps with heroin withdrawal
Catapres
Mechanism of action of calcium channel blocker’s
Block calcium channels and reduce intracellular calcium and reduce vasoconstriction
Mechanism of action of non-dihydropyridine’s
Decrease force of contraction
vasodilation
slow SA and AV node
Mechanism of action of dihydropyridine’s
Decrease SVR an arterial pressure
Side effect of dihydropyridine’s
Reflex tachycardia
Norvasc
Amlodipine
Dihydro CCB
Procardia
Nifedipine
Dihydro CCB
Cardiazem
Diltiazem
Nondihydro
Side effect of Cardiazem
Peripheral edema
First-line antihypertensive for a fib patients
Cardiazem
What does the LAD supply?
The septum in the anterior ventricular wall
Symptoms of mitral regurgitation
Dyspnea
fatiguability
palpitation
left-sided heart failure
Most common cause of mitral regurgitation
MVP
Hello systolic murmur at the apex of the heart
Mitral regurgitation
Mid systolic click and late systolic murmur
MVP
Most common cause of mitral stenosis
Rheumatic heart disease
Symptoms of mitral stenosis
Dyspnea hemoptysis palpitations fatigue
Symptoms of aortic stenosis
Dyspnea
exertional syncope
pulmonary congestion
fatigue
Paradoxically split s2
Aortic stenosis
Acute causes of aortic regurgitation
Endocarditis
aortic dissection
Trauma
Chronic causes of aortic regurgitation
Rheumatic heart disease
bicuspid valve
Marfan syndrome
Symptoms of tricuspid regurgitation
Dyspnea
systemic vascular congestion
Symptoms of tricuspid stenosis
Fatigue
systemic vascular congestion
Most common cause of tricuspid stenosis
Rheumatic heart disease