CARDIO 269 Flashcards
What causes a positive ionotrophy
catecholamines, digoxin
what causes a negative ionotrophy
Uncompensated HF, narcotic overdose
what causes an increases venous return
Fluid Infusion, sympathetic activity
what causes a dec in venous return
Acute Hemorrhage, Spinal anesthesia
what increases TPR
Vasopressors
what causes a dec in TPR
AV shunt, exercise
what is isovolumetric contraction
period btw mitral valve closure an aortic valve opening
Period of highest oxygen consumption
period btw the time the aortic valve opens and closes is called
systolic éjection
period btw the aortic valve closure and the mitral valve opening is called
isovolumetric relaxation
period just after mitral valve open is called
rapid filling
what is reduced filling
period just BEFORE mitral valve closes
when do u see an S3 sounds
when mitral valve opens
when do you see s4 sound
just before mitral valve closes
when do you hear the s1 sound and where is it loudest ?
mitral and tricuspid valve closure, loudest mitral area
what drug worsens lithium toxicity (Tremors, confusion, Ataxia )
NSAIDS, Thiazides and ACE inhibitors
what are the side effects of methotrexate
mouth ulcers, nausea, hepatotoxicity (inc AST & ALT), bone marrow suppression (take Folinic acid for reversal) Pulmonary fibrosis
what is metalloproteinease and what it his function
a zinc containing enzyme that degrades collagen, laminin and fibronectin.
it is essential for proper tissue remodeling during wound healing.
what disease do you use Hydroxychloroquine to treat
RA & SLE