Cardio

Question 1

What alteration does ACE-I orARB do in K?

Answer 1

Hyperkalemia

Question 2

ACE-I

Answer 2

Lisinopril
Captopril
Enalapril
Ramipril

MOA: Block aldosterone action

Used in:
- HTN
- HTN and albuminuria
- HTN and CKD stage 3 or higher
- HTN and DM

SE:
- Hyperkalemia
- Cough (MC in female than in men)
- Angioedema
- Dyspnea (independent of cough and angioedema)
- Fetotoxic

CI in pregnancy

Question 3

Dihydropyridine CCB

Answer 3

Verapamil
Diltiazem

Action: negative inotropic (force of contraction) and negative chronotropic (related to rate) effect

Question 4

Nondihyropyridine CCB

Answer 4

Amlodipine (Norvasc, Katerzia)
Nicardipine
Nifedipine
Felodipine
Isradipine

Action: vaso-selective

SE: edema, flushing, HA, rash, gingival hyperplasia

** Not inidcated as first line in pts with HTN and hx of stroke