cardio Flashcards
treatment for acute MI?
MONA: morphine, O2 (if sats are <94%), nitrates, aspirin
pharmacology of spironolactone?
inhibition of aldosterone receptor at K+/Na+ channel in the distal tubules
list some risk factors for hypertension
High caffeine consumption, Sedentary lifestyle, Smoking, Type A personality, alcohol, family history, increasing age
presentations of mitral regurgitation?
SOB, fatigue, pan-systolic high-pitched “whistling” murmur at apex, may radiate to left axilla
presentations of aortic stenosis?
syncope, angina, ejection systolic murmur
presentations of aortic regurgitation?
syncope, angina, early diastolic / austin flint murmur
presentations of mitral stenosis?
SOB, fatigue, low pitched, “rumbling” mid-diastolic murmur
MI ECG changes?
ST elevation, T wave inversion, abnormal Q wave
what underlying heart condition can predispose you to strokes?
atrial fibrillation
what framework determines heart attack risk in those with hypertension?
QRISK2 score
describe the correct order for the electrical conduction of the heart?
SA node -> atria -> AV node -> bundle of His -> Purkinje fibres -> L and R bundle branches -> ventricles
explain the pathophysiology of aortic stenosis
coarctation (narrowing) of the aortic valve typically either due to calcification or bicuspid valve
XR for mitral stenosis?
enlarged left and right atriums
List some clinical signs you might find on examination or on a chest X-ray in heart failure
ABCDE:
- Alveolar oedema
- kerley B lines
- Cardiomegaly
- Dilation of the upper lobe vessels
- pleural Effusion
What marker might you find in blood that could be indicative of heart failure?
BNP
List 3 investigations that you would want to do for initial investigations of infective endocarditis
blood cultures, echocardiogram, ECG, FBC (anaemia), urinalysis
Define atherosclerosis
build up of lipids, macrophages and smooth muscle cells in the intima of arteries
Other than chest pain, name 4 other symptoms or signs you may find on the history or examination in a STEMI
sweating, hypotension, N/V, dizziness, SOB, anxiety, palpitations, pallor
Name the 4 cardiac defects involved in Tetralogy of Fallot.
ventricular septal defect, pulmonary stenosis, right ventricular hypertrophy, overriding aorta
what does 1st degree HB show?
prolonged PR interval
what does 2nd degree type I (Mobitz I or Wenckebach) show?
progressive prolongation of the PR interval followed by a dropped QRS complex
what does 2nd degree type II (Mobitz II) show?
intermittent non-conducted P waves without progressive PR prolongation
what does 3rd degree HB show?
absence of AV conduction; no association between P waves and QRS complexes
define thrombosis
formation of a blood clot inside a blood vessel which obstructs flow
define embolism
blocked vessel caused by a foreign body e.g. blood clot or air bubble
define infarction
death of cells due to a reduced or absent blood supply
define ischaemia
restriction in blood supply to tissues causing a shortage of oxygen that is needed for cell function
give 4 functions of the RAAS system
- increased sympathetic activity and arteriolar vasoconstriction therefore increases HR/BP
- increased tubular reabsorption of Na and Cl and K+ excretion
- increased aldosterone secretion resulting in Na reabsorption in DCT
- ADH secretion leading to H2O reabsorption
- overall: salt and water retention and an increase in BP
what is the difference between essential and secondary hypertension?
Essential hypertension occurs independent of any identifiable cause, secondary hypertension occurs as a result of an identifiable cause
state 4 causes of secondary hypertension
renal artery stenosis, chronic renal disease, primary hyperaldosteronism, stress
which part of the heart is likely to be affected if there is ST elevation in leads V3 and V4?
anterior
abnormalities in leads II, III, and aVF - Which coronary artery is most likely to be implicated?
right coronary
what is the treatment given post MI?
ACEi, dual antiplatelet therapy e.g. clopidogrel and aspirin/BBlocker, statin
what is given as acute management for supraventricular tachycardia?
valsalvar manoeuvre - nose and mouth is held during forceful expiration to stimulate the vagus nerve to return the heart into sinus rhythm
Which tool assesses starting anticoagulation in patients with stroke risk due to atrial fibrillation?
CHA2DS2-VASc