Cardio Flashcards
Early diastolic murmur
Aortic regurgitation -
Early diastolic murmur (best heard at left sternal edge, with patient sat forward and breath held in expiration). Look for: pulse large volume and collapsing, de Musset's sign (head nodding), Corrigan's sign (visible carotid pulsations), displaced forceful apex beat. Also: check BP (wide pulse pressure). Look for hyperdynamic circulation: Traube's sign 'pistol shot femorals' Quincke's sign of nail bed capillary pulsations, Duroziez's sign of a to-and-fro murmur. Causes: Rheumatic fever, hypertension, atherosclerosis, endocarditis, bicuspid aortic valve. Also associated with: Marfan's syndrome, ankylosing spondylitis, rheumatoid arthritis, syphilis.
Congenital pulmonary valve disease
Downs (trisomy 21)
Noonan (short stature, micrognatia, wideey spaces eyes, ears back)
Turner (X chromosome, short stature and reporuductive failure)
Causes of mitral regurgitation
Degenerative (age related) Underlying MVP - note connective Tissue Disorders IE Rheumatic Fever MI (papillary muscle rupture)
Investiagations to request: mitral regurgitation
ECG, Fundoscopy, Urine dipstick
Bloods - inflammatory markers, FBC (anaemia), U&E
Echo - pulmonary htn, concommitant lesions, ejection fraction
Complications of aortic stenosis
Endocraditis - splinters, ON (finger pulp), JL (palm), Roth spots (retina), temperature, splenomegaly, haematuria
LVD - displaced apex beat, bibasal crackles
Concution problems
DDx ESM
HOCM VSD PS Aortic sclerosis Aortic flow - high output states
Causes of AS
Biscuspid AV (congenital) Aquired (age, rheumatic)
Severity of AS
ASD Angina - 5 Syncope - 3 Dyspnoea - 2 50% mortality
Dukes Criteria for IE
Major –> Typical organism on 2 blood cultures, Echo evidence of IE
Minor –> Pyrexia, echo suggestive, predisposition (e.e.g prosthetic valve), embolic phenomena, vasculitic phenomena (ESR, CRP), atypical organism on blood culture
2 major or 1 major and 2 minor or 5 minor
Management of AS
Asymptomatic - none, good dental health, regular review of symptoms and echo findings to assess gradient and LVF
Surgical - AVR +/- CABG (operative 3-5% mortality
Percutaneous - baloon aortic valvuloplasty or TAVI
NNT for TAVI 5 at 1 year
Investigating ESG
ECG - LVH, conduction defect (e.g. 1*HB)
CXR - ?valvular calcification, ?cardiomegaly
Echo - mean gradient 40mmHg, valve area <1.0 severe
Angiography - ?extent of co-existing CAD
AR eponymous signs
deMussets - head bobbing Corrigans - visible carotid pulsations Quicke's - nail bed pulsation Durosier's - diastolic murmur proximal to femoral artery compression Traube's - pistol shot femoral
DDx aortic regurg
Valve leaflet - endocarditis (acute), rheumatic fever (chroinc)
Aortic root - dissection/trauma (acute), dilatation due to marfans and hypertension, aortitis (ank spond, syphilis, vasculitis
Causes of a collapsing pulse
AR Prednancy PDA Pagets Anaemia Thyrotoxicosis
Investigating AR
ECG - lateral TWi
CXR - cardiomegaly, widened mediastinum
TTE/TOE - severity, LVEF and dimentions, root size, jet width
Cardiac catheterisation - grade severity and check coronary patency