Cardio Flashcards
How common are congenital cardiac abnormalities?
1-2% of the population. 8:1000 are significant
What are the different ways congenital cardiac disease can present? What are some cardiac?
- Cyanotic (right to left shunt): Tetralogy of Fallot, TGA
- Acyanotic/breathless (left to right): VSD, PDA, ASD
- Outflow obstruction (asymp/collapse): PS, AS, coarctation
What are some causes of congenital cardiac disease? Which CHD they classically associated with?
Chromosomal abnormality:
- Down’s (30%): VSD, AVSD
- Edwards + Patau: complex
- Turner’s (15%): bicuspid aortic valve (AS), coarctation
- DiGeorge (80%): aortic arch anomaly, ToF
- Noonan: HOCM, ASD
Maternal factors:
- Rubella: PS, PDA
- SLE: complete heart block
- Warfarin, alcohol, DM
What is the common cardiac defect in Down’s?
VSD, AVSD
What is the common cardiac defect in Turners?
Bicuspid aortic valve causing AS, coarctation
Describe the changes that occur in the fetal circulation at birth
At birth, liquid out of lungs -> decreased intrathoracic pressure -> decreased resistance in pulmonary vessels -> increased blood flow
Decrease R sided pressures and increased left sided (due to return from pulmonary) -> closure of foramen ovale
After several days: PDA closes
What are some features of innocent murmurs?
- Soft, blowing
- Left sternal edge
- Systolic
- No systemic features (breathlessness, cyanosis)
- Normal pre and post-ductal sats
What are some causes of innocent murmurs?
- Anaemia
- Infection/illness
How does heart failure present in children?
SOB (worse on feeding/exertion), poor feeding, sweating
Poor weight gain, ^HR and RR, murmur, enlarged heart, hepatomegaly
What are some causes of heart failure in children?
Neonates- obstruction eg coarctation. Also AVSD
Infants- left-to-right shunt eg VSD, large PDA
Children- Eisenmenger, RHD, cardiomyopathy
Why can coarctation cause collapse in the first few days of life? What is the term that is used for this type of condition? What is the treatment?
Severe obstruction means arterial perfusion is supplied by the DA. Closure occurs in the first few days of life -> rapid worsening + decreased flow
This is called duct-dependent circulation, and treatment is to maintain the DA with prostaglandins
What is Eisenmenger syndrome? What causes it?
A complication of untreated left-to-right shunt, where high flow through the pulmonary vessels causes pulmonary hypertension -> eventual reversal of the shunt -> cyanosis.
Caused by VSD, ASD, PDA
A newborn boy becomes cyanotic after several hours. Saturations are 88%. What is the initial management?
ECG and CXR
What are the signs of ASD on examination and CXR?
Examination:
Ejection systolic murmur at upper left sternal edge (due to high flow across pulmonary valve)
Fixed and widely split S2
CXR:
Cardiomegaly
Pulmonary oedema, enlarged arteries
What is the best investigation for diagnosing CHD?
Echo
What are the types of ASD? How are they managed?
- Secundum (most): hole in middle of the septum. Cardiac catheterisation later in childhood
- Primum, part of partial AVSD: assoc with Down’s. Surgical correction later in childhood.
What is a small VSD?
<3mm
How does a VSD present?
Small: asymptomatic
- Pansystolic murmur, lower left sternal edge
- Quiet P2
Large: cause heart failure, recurrent chest infection
- Soft pansystolic murmur, apical mid-diastolic murmur
- Loud P2
- CXR shows cardiomegaly, pulm oedema, enlarged arteries