Cardiac Poison Flashcards
Mnemonic
Car DONA
cardiac
Digitalis
Oleander
Nicotine
Aconite
Active principle of nicotine
Nicotine
Nornicotine
Anabasine
Active principle of digitalis
Digoxin
Digitoxin
Digitalin
Digitonin
Types of oleander
Pink/white oleander
Yellow oleander
Active principle of pink oleander
Oleanderin
Nerin
Folinerin
Active principle of yellow oleander
Theve tin
Thevetoxin
Active principle of aconite
Aconitine
Pseudoaconitine
Indaconitine
Common oleander is white or yellow
White
Aconite vs horse radish
Smaller conical vs larger cylindrical
Dark brown vs yellow white
Sweet taste earth smell vs pungent taste pungent smell
Acute poisoning of cardiac poisoning
Cardiac arrhythmia
Tremors ,convulsions
Nausea ,vomiting
MOA of digoxin,oleanderin and thevetin
Inhibit sodium potassium ATPase pump
Hyperkalemina
Arrhythmia
Fatal dose of aconite
1 to 2 gm of root
Features of aconite
Perioral parasthesia
Arrhythmia
Hippus
Fetal dose of aconite
1 to 2 gm of root
Lanceolate leaves present in yellow or white oleander
White
Chronic poisoning of nicotine
Acute symptoms plus
Cough , wheeze
Toxic amblyopia ( narrowing of field of vision , blurring)
Blindness
Rx of toxic amblyopia
Mecamylamine
Is cyanide a cardiac poisoning
Yes
MOA of Aconite
Voltage sensitive sodium channels
MLI of aconite
Accidental poisoning
Ideal homicidal
Cheap,low fatal dose,sweet taste,destroyed by putrefaction
