cardiac muscle structure and function Flashcards

1
Q

cardiac muslces are ___

A

striated

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2
Q

Cardiac muscle are not under ___ ____ control

A

direct neural

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3
Q

Ca2+ binds to ___ to regulate actomysosin interaction

A

troponin

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4
Q

Cardiac muscles are ___, ____, and ______ than skeletal muscles

A

shorter, narrower, richer in mitochondria

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5
Q

ATPase activity of myoscin is ___ in cardiac than skeletal

A

slower

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6
Q

Gap junctions allow for

A

low resistance pathway for electrical currents

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7
Q

Desmosomes provide

A

adhesion/assure force generated in one cell passes to other

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8
Q

Cardiac muscle cells connect with each other through _______

A

intercalated disc

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9
Q

Intercalated discs coincide with ____, which contains ___ and ____

A

z discs,

desmosomes and gap junction

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10
Q

myofiber = ?

A

small bundle of muscles

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11
Q

Myofibirils

A

end to end arrays of identical sarcomeres

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12
Q

Sarcomeres

A

contractile units

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13
Q

Thin filament

A

actin

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14
Q

Thick filament

A

myosin

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15
Q

Actin binds ___ and ___

A

tropomyosin; troponin

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16
Q

Myosin is composed of ___

A

2 heavy chain, 4 light chain

17
Q

Troponin C is a ___shaped protein with __ Ca binding site

A

dumbell

one (skeletal has 2)

18
Q

Troponin I - Unique N terminal extension of __ amino acid; PKA ___ for ___ responsiveness of heart

A

32
phosporylate
adrenergic

19
Q

Mechanism behind length - tension relationship

A

extend overlap, change in sensitivity to myofilament to ca, increased Ca release