cardiac muscle structure and function Flashcards
cardiac muslces are ___
striated
Cardiac muscle are not under ___ ____ control
direct neural
Ca2+ binds to ___ to regulate actomysosin interaction
troponin
Cardiac muscles are ___, ____, and ______ than skeletal muscles
shorter, narrower, richer in mitochondria
ATPase activity of myoscin is ___ in cardiac than skeletal
slower
Gap junctions allow for
low resistance pathway for electrical currents
Desmosomes provide
adhesion/assure force generated in one cell passes to other
Cardiac muscle cells connect with each other through _______
intercalated disc
Intercalated discs coincide with ____, which contains ___ and ____
z discs,
desmosomes and gap junction
myofiber = ?
small bundle of muscles
Myofibirils
end to end arrays of identical sarcomeres
Sarcomeres
contractile units
Thin filament
actin
Thick filament
myosin
Actin binds ___ and ___
tropomyosin; troponin
Myosin is composed of ___
2 heavy chain, 4 light chain
Troponin C is a ___shaped protein with __ Ca binding site
dumbell
one (skeletal has 2)
Troponin I - Unique N terminal extension of __ amino acid; PKA ___ for ___ responsiveness of heart
32
phosporylate
adrenergic
Mechanism behind length - tension relationship
extend overlap, change in sensitivity to myofilament to ca, increased Ca release