Cardiac Meds, Adrenergic/Vasopressin Receptors, etc Flashcards

1
Q

Alpha 1 Receptors - Located where? Effect?

A

Location: Systemic arterioles (abdominal viscera, coronary, skin, skeletal muscle), veins, pulmonary arterioles

Effect: vasoCONSTRICTION

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2
Q

Alpha 2 Receptors - Located where? Effect?

A

Location: Presynaptic sympathetic nerve terminals, CNS

Effect: vasoDILATION

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3
Q

Beta 1 Receptors - Located where? Effect?

A

Location: HEART

Effect: Inotropy, chronotropy, dromotropy

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4
Q

Beta 2 Receptors - Located where? Effect?

A

Location: Systemic arterioles (abdominal viscera, coronary, skeletal muscle), veins, pulmonary arterioles

Effect: vasoDILATION

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5
Q

Dopamine Receptors - Located where? Effect?

A

Location: Systemic arterioles (abdominal viscera, renal, coronary)

Effect: vasoDILATION

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6
Q

V1 Receptors - Located where? Effect?

A

Location: Vascular smooth muscle

Effect: vasoCONSTRICTION

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7
Q

V2 Receptors - Located where? Effect?

A

Location: Renal distal convoluted tubule and collecting duct

Effect: Antidiuresis

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8
Q

What are the receptors and effects of: Norepi?

A

alpha1, alpha2 > beta1

vasoCONSTRICTOR

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9
Q

What are the receptors and effects of: Epi?

A

alpha1, alpha2, beta1, beta 2

Inotrope and vasoCONSTRICTOR

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10
Q

What are the receptors and effects of: Phenylephrine?

A

alpha1

vasoCONSTRICTOR

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11
Q

What are the receptors and effects of: Dopamine?

A

alpha1, alpha2, beta1, beta2, dopamine

Inotrope and vasoCONSTRICTOR

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12
Q

What are the receptors and effects of: DoBUTamine?

A

beta1, beta2

Inotrope and vasoDILATOR

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13
Q

What are the receptors and effects of: Isoproterenol?

A

beta1, beta2

Inotrope and chronotrope

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14
Q

What are the receptors and effects of: Milrinone?

A

Phosphodiesterase 3 inhibitor

Inotrope and vasoDILATOR

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15
Q

What are the receptors and effects of: Vasopressin

A

V1, V2
vasoCONSTRICTOR in catecholamine-resistant shock
OR just think once the pt is tanked up you can add some VASCULAR TONE which will improve blood flow.

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16
Q

Labetalol

A

non-selective beta+alpha1 blocker
alpha blockade reduces vascular smooth muscle tone (increasing vascular capacitance and directly decreasing blood pressure)

Long half life – 5.5hrs, hard to titrate

17
Q

When are beta-blockers contraindicated?

A

Asthma, bradycardia, first-degree heart block, decompensated heart failure