Cardiac markers

Question 1

Troponin

Answer 1

Cardiac necrosis or MI

Normally is absent in healthy

Question 2

Creatine Kinase (CK)

Answer 2

Tissue necrosis or injury

Cardiac version:

• Rises in 3 hours
• Peaks 24 hours
• Normal within 3 days

Question 3

Homocysteine

Answer 3

Serum test

Breakdown of AA (?)

Causes vessel inflammation, forms plaque and clots if too high

Can predict Coronary Artery Disease

controlled by B6/12

Question 4

C reactive Protein

Answer 4

Produced by liver

Marker for inflammation

Can indicate risk for CAD, linked to Acute coronary syndrome

Appears and disappears quick

Normally rises with autoimmune disease

Question 5

Brain Natriuretic Peptide (BNP)

Answer 5

Protein stored in ventricle tissue

Released when ventricular diastolic pressure rises

Ventricular hypertrophy, HTN, CHF, fluid overload

Normal range: under 100pg/mL

Severe range: Over 700pg/mL