CARDIAC MAGNETIC RESONANCE IMAGING Flashcards

1
Q

What is cardiac magnetic resonance (CMR)?

A

A non-invasive imaging technique that uses a strong magnet, radiofrequency pulses, and gradient magnetic fields to produce detailed images of the heart.

CMR is essential for evaluating various cardiac conditions without ionizing radiation.

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2
Q

What strength of magnet does CMR typically use?

A

1.5 to 3.0 Tesla

This is equivalent to 30,000–60,000 times the strength of the earth’s magnetic field.

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3
Q

What fundamental process allows CMR to produce images?

A

The alignment of positively charged protons in a magnetic field, followed by relaxation and signal emission.

This involves T1 and T2 relaxation components.

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4
Q

What is k-space in CMR?

A

A data space where collected signals are organized before creating an image.

It is essential for image reconstruction in CMR.

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5
Q

How does CMR differ from echocardiography?

A

CMR does not expose patients to ionizing radiation and has superior contrast-to-noise and signal-to-noise ratios.

This allows better delineation of tissue borders.

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6
Q

What are some limitations of CMR?

A

Availability, portability, contraindications, difficulty with irregular rhythms, and claustrophobia.

CMR requires specialized facilities and trained personnel.

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7
Q

What are common indications for CMR?

A
  • Evaluation of chest pain syndrome
  • Assessment of coronary anomalies
  • Evaluation of LV function after myocardial infarction
  • Assessment of myocardial viability
  • Evaluation of myocarditis
  • Evaluation of specific cardiomyopathies
  • Characterization of cardiac valve dysfunction
  • Evaluation of cardiac masses
  • Assessment of congenital heart disease
  • Evaluation for aortic dissection

These indications highlight CMR’s versatility in cardiac assessment.

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8
Q

What pulse sequences are commonly used in CMR?

A
  • Bright blood gradient echo sequences
  • Dark blood spin echo sequences
  • Steady-state free precession sequences
  • Inversion recovery sequences

These sequences help in visualizing different aspects of cardiac structures.

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9
Q

What is late gadolinium enhancement (LGE) imaging?

A

A CMR technique used to identify myocardial scar/fibrosis by administering gadolinium-based contrast agents.

LGE imaging helps in assessing areas of scar after myocardial infarction.

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10
Q

Can CMR be used for stress testing in patients with chest pain?

A

Yes, CMR stress testing can assess flow-limiting coronary stenosis in patients with intermediate pretest probability of CAD.

Methods include vasodilator perfusion CMR and dobutamine stress function CMR.

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11
Q

What is the role of CMR in evaluating ventricular function?

A

CMR is the reference standard for assessing ventricular volumes, ejection fraction, and ventricular mass.

It is particularly useful after myocardial infarction or in heart failure.

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12
Q

What specific cardiomyopathies can CMR assess?

A
  • Infiltrative diseases (e.g., amyloid, sarcoid)
  • Hypertrophic cardiomyopathy
  • Arrhythmogenic right ventricular cardiomyopathy

CMR can reveal unique LGE patterns associated with various cardiomyopathies.

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13
Q

What is the importance of T1 and T2 mapping in CMR?

A

They provide direct quantification of myocardial tissue properties, aiding in the assessment of conditions like edema and fibrosis.

These mapping techniques are evolving for better accuracy in diagnoses.

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14
Q

How can CMR be used in the context of myocardial infarction?

A

CMR identifies myocardial necrosis, microvascular obstruction, and myocardial thrombus using LGE imaging.

It also assesses the likelihood of recovery of function with revascularization.

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15
Q

What role does CMR play in assessing valvular disease?

A

CMR assists in evaluating valve lesions when echocardiographic images are technically limited and provides quantitative assessments of stenosis and regurgitation.

Techniques such as phase-contrast imaging are utilized for flow measurements.

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16
Q

What technique is used to assess flow volumes of the great vessels?

A

Phase-contrast imaging

This technique is analogous to Doppler imaging in echocardiography.

17
Q

What is a major advantage of four-dimensional flow techniques in cardiac imaging?

A

Provides flow data in all three dimensions of space over time

This helps assess regurgitant or stenotic lesions more comprehensively.

18
Q

What is a limitation of four-dimensional flow techniques?

A

Length of acquisition and limited ability to postprocess data

19
Q

Why is CMR often considered the best modality for assessing congenital heart disease?

A

Unique ability to assess heart and circulation in three-dimensional space and obtain hemodynamic data

20
Q

What can CMR accurately measure in patients with congenital heart disease?

A

LV and RV volumes and function

21
Q

What is a significant benefit of CMR for young patients requiring multiple imaging studies?

A

No ionizing radiation exposure

22
Q

What is a major limitation of CMR in patients with congenital heart disease?

A

Susceptibility to artifacts from previous surgeries

23
Q

What is CMR’s effectiveness in assessing cardiac masses?

A

Good modality for assessment and tissue characterization

24
Q

What is a key limitation of CMR in characterizing tumor tissue?

A

Initial hopes for noninvasive biopsy have not been fully realized

25
Q

What other clinical uses does CMR have?

A

Assessment of pericardial conditions and pulmonary vein anatomy

26
Q

What does CMR assess in constrictive pericarditis?

A

Thickness of the pericardium and signs of inflammation

27
Q

What are some common contraindications to CMR?

A

Ferromagnetic objects and certain metallic implants

28
Q

Can CMR be performed in patients with implanted cardiovascular devices?

A

Yes, most devices are nonferromagnetic or weakly ferromagnetic

29
Q

What is nephrogenic systemic fibrosis (NSF)?

A

A fibrosing condition affecting skin, joints, muscles, and internal organs

30
Q

What are the main risk factors for developing NSF with GBCAs?

A
  • Advanced renal disease
  • Recent vascular surgical procedures
  • Dialysis
  • Acute renal failure
  • Higher doses of contrast agent
31
Q

What is the time interval between GBCA administration and the onset of NSF?

A

60 to 90 days

32
Q

What concern has arisen regarding gadolinium-based contrast agents?

A

Brain deposition of gadolinium

33
Q

Is there evidence of clinical consequences from gadolinium brain deposition?

A

No studies have demonstrated clinical, behavioral, or biological consequences

34
Q

What is the significance of the Revo MRI SureScan system?

A

First MRI-safe pacemaker approved by the FDA

35
Q

What is the Evera MRI ICD?

A

First ICD approved by the FDA as an MRI-conditional device

36
Q

What should be done prior to GBCA administration in patients with advanced renal disease?

A

Carefully weigh risks and benefits, consider alternate imaging modalities