CARDIAC INFECTIONS Flashcards

1
Q

3 STAGES OF KAWASAKI?

A

acute–neutrophilic, aneurysms
subacute–lymphatic, vasculitis, eosinophils
convalescent–smooth muscle, stenosis, thrombosis

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2
Q

criteria for kawasaki diagnosis?

A

FEVER+

4/5:
דלקת בלחמית דו''צ ללא מוגלה 
לשון תות
לימפואדנופתיה חד צדדית לפחות 1.5 ס''מ
בצקת, אודם וקילופים בכפות ידיים/רגליים
פריחה
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3
Q

what other signs/symptoms can be seen in Kawasaki?

A
GI issues
cough/runny nose
arthritis (from week 2-3)
leukocytes in urine with negative culture
hepatitis, hydrops of gall bladder
agitation
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4
Q

Kawasaki: what long term effects can we see?

A

cardiac trouble including CHF

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5
Q

which is the most dramatic long-term effect of Kawasaki?

A

coronary aneurism

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6
Q

Kawasaki: what labs help?

A
hyponatremia
hypoalbuminemia
leukocytes in urine
thrombocytosis
ESR and CRP raised

cath lab will show aneurysms

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7
Q

Kawasaki: what symptoms will we see at each of the 3 phases?

A

אקוטי-1-2 שבועות חום ותסמינים אחרים. מיוקרדיטיס, חולשה
סב-אקוטי -3 שבועות קילופים, טרומבוציטוזיס, **אנוריזמות קורונריות, עוד בעיות בקורונריים, מוות.
קונבלאסנט-הפחתת עד סיום תסמינים, התנרמלות מעבדת דלקת, מצב כרוני.

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8
Q

what does Atypical Kawasaki look like?

A

פחות סימפטומים )2-3( בקרייטיריון ויותר עדות מעבדתית.

נראה יותר אצל תינוקות מתחת לגיל שנה.

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9
Q

what is the treatment for Kawasaki?

A

IVIG
ASPIRIN
אנטיקואגולנטים (בעיקר עם יש CORONARY ARTERY ABNORMALITIES(
יש להתחיל טיפול תוך 10 ימים מהופעת חום

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10
Q

what are the AE’s of IVIG?

A
חום
כאב ראש
הקאות
טרומבואמבוליזה
אי ספיקת כליות
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11
Q

what must be considered about a patient receiving IVIG?

A

יש לדחות חיסונים חי מוחלש 9-11חודשים

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12
Q

What helps in improving the prognosis of someone with Kawasaki?

A

טיפול מוקדם תוך 10 דימים מהופעת חום

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13
Q

what is the cause of RHEUMATIC FEVER?

A

certain strains of GROUP A STREPTOCOCCUS PNEUMONIA (GAS)

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14
Q

what is the common age range for RHEUMATIC FEVER?

A

5-15 yrs old

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15
Q

when do we almost never see RHEUMATIC FEVER?

A

under the age of 3, therefore usually don’t treat sore throat then.

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16
Q

what do we call the diagnostic criteria of RHEUMATIC FEVER?

A

JONES CRITERIA

17
Q

what does JONES CRITERIA entail?

A

If first event: pos culture for strep/strep antigen and…
2 major
or 1 major+ 2minors

if repeat event:
can be 3 minors

MAJORS: carditis, polyarthritis, erythema marginatum, subcutaneous nodules, chorea

MINORS: arthralgia, fever, LABS w/: high ESR, high CRP, prolonged PR interval

18
Q

when do you not need JONES CRITERIA to diagnose RHEUMATIC FEVER?

A

CHOREA
SIG heart disease after throat infection
high risk populations or if reinfection

19
Q

what are other signs and symptoms of RHEUMATIC FEVER?

A
MIGRATORY ARTHRITIS
carditis
sydenham chorea
erythema marginatum
subcutaneous nodules
20
Q

what is the treatment for RHEUMATIC FEVER?

A

AB
אנטי-דלקתי (NSAIDS, ASPIRIN, STEROIDS)
LUMINAL/chloropromzine if have chorea

21
Q

what is important to consider for treatment of RHEUMATIC FEVER?

A

להתחיל תוך 10 יום
תלוי רמת פגיעה לבבית
תלוי אם אבחנה חוזרת