Cardiac Imaging Flashcards

1
Q

Types of Cardiac Testing

A
  • EKG
  • Ambulatory ECG Monitoring
  • Stress test
    • Exercise
    • Pharmacologic
  • Echocardiogram
    • Stress echocardiogram
  • CT scan
  • MRI
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2
Q

EKG

Indications

A
  • Symptomatic patients
    • CP, palpitations, fatigue w/SOB, syncope (pass out), seizure
  • Eval/monitoring of:
    • Audible abnormalities (arrhythmia, murmur)
    • Suspected electrolyte imbalance
    • PE
    • Congenital heart disorders
    • CHF
    • Cardiomyopathy (enlargement)
    • Poisonings/electrocution
  • Drug monitoring - need regular EKG monitoring
    • Drugs that prolong QT (lithium, psych meds)
  • Presence of implanted defibrillator/pacemaker (yearly EKG
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3
Q

Screening EKGs

USPSTF

A
  • Adults at low risk of CVD events: Recommend AGAINST EKG screening (Grade D) → can lead to unnecessary tests
  • Adults at intermediate or high risk: Insufficient evidence for screening (Grade I)
  • Athletes - sports physical
    • History and physical most important
      • Worried about electrical abnormalities (asymptomatic arrhythmias) while exercising)
  • Pre-operative exams
  • Certain occupations may require screening EKG: cataract

If patient has no symptoms indicating an EKG → no need to test again

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4
Q

How to assess CVD risk by USPSTF?

A

Use Pooled cohort calculator

10-year ASCVD risk < 7.5% = low

“” >/= 7.5% elevated risk

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5
Q

Ambulatory EKG monitoring

A

Provides data over extended period of time

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6
Q

Ambulatory EKG monitoring Indications

A
  • Arrhythmias s/s
  • Eval effectiveness of arrhythmia therapy
  • Screening for asymptomatic arrhythmia
  • Eval prognosis post ACS
  • Assess for silent ischemia in someone with known/suspected CAD
    • DM, women
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7
Q

What arrhythmia s/s indicate for ambulatory EKG monitoring?

A
  • Unexplained syncope/near syncope
  • Episodic dizziness, unexplained recurrent palpitations
    • Frequent palpitations/palpitations associated w/other s/s: SOB, dizziness, etc
    • Vasovagal event precipitated by something (feel like I’m going to pass out)
    • Passing out
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8
Q

Types of ambulatory Monitoring

A
  • Continuous EKG (Holter)*
  • Event (loop) monitors
  • Patch monitors*
  • Mobile Cardiac Outpatient Telemetry (MOCT)
  • Insertable cardiac monitoring

*** = see in primary care

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9
Q

Holter monitor

A
  • Best for daily or near daily symptoms and/or if continuous monitoring of all cardiac activity is required (gives you most info for shortest time)
    • Daily palpitations or dizziness
    • Assessment of rate control in afib (short time period to see rate) don’t need 30days, only snippet
  • Continuously records heart rhythm
  • Usually worn for 24-48 hrs
  • 3-5 electrodes on chest
  • Patient keeps symptom diary
    • Hit a button
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10
Q

Patch monitor

A
  • Good for pts w/less frequent s/s or need for longer monitoring
    • Weekly or every other week s/s
  • More convenient and easier for pt to tolerate than Holter
  • Small all in one device - ONE electrode
  • Record only single lead but can record continuously for up to 30 days
    • 3, 7, 14, or 30d
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11
Q

Event Monitor

types

A
  • Good for less frequent symptoms (weekly or bi-weekly)
  • Not recording unless patient hits the button when they’re experiencing s/s → problem is the monitor may not be able to capture the duration while it’s occuring
  • Pre-symptom memory loop recorders - “continuous loop event recorder” - always recording and erasing data
    • Not for asymptomatic
  • Post-event recorders - “non-looping event recorder”
    • May miss rhythm problem
  • Auto-detect - GOOD FOR ASYMPTOMATIC automatically sends data to provider to interpret
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12
Q

Insertable cardiac monitor

A
  • May be needed if other event monitors can’t provide enough data
  • Use if symptoms are infrequent
  • Size of pack of gum
  • Can be programmed to record when patient activates it or when s/s occur
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13
Q

Cardiac stress tests

Indications? What limitation and other option is there?

A
  • Exercise stress testing used in symptomatic, intermediate-risk patients who can exercise and who have interpretable EKG results
  • No exercise → pharmacologic stress test
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14
Q

When is stress testing NOT used?

A
  • In high-risk patients actively evaluated or treated for ACS; it may be used once ruled out ACS for risk stratification
  • Exercise stress testing not recommended in asymptomatic, low-risk patients
  • None on pt w/acute MI, going to ER w/CP → have it later on
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15
Q

Stress testing indications (7)

A
  • New CP or angina (not current) ASK THIS!
  • Known CAD and new/worsening symptoms (cardiac disease)
  • Hx of PCI/re-vascularization (stenting)
  • Valvular heart disease - stress ECHO
  • New HF or cardiomyopathy - evaluate ischemia as cause
  • Pre-operatively in pts w/known cardiac conditions
  • Assess heart health prior to cardiac rehab or new exercise regimen
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16
Q

Contraindications to Stress Testing

Absolute!

A
  • Acute MI w/in 48hrs
  • Acute myocarditis/pericarditis
  • Rapid Afib or ventricular arrhythmias
  • Symptomatic severe aortic stenosis
  • Severe anemia, acute illness, infection
  • Uncontrolled hyperthyroidism
  • Acute aortic dissection, PE, recent CVA (stroke)
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17
Q

Contraindications to stress testing

Relative - cardiology would decide

A
  • Hypertrophic obstructive cardiomyopathy
  • Suspected L main disease > 50%
  • Severe HTN, > 200/110 mmHg
  • Congestive heart failure (CHF)
  • Severe ST depression at rest (unstable angina)uPermanent Pacemakers/ LBBB
    • Left bundle branch blocks
    • Specific way to stress ppl with these to get data
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18
Q

What are the components of a stress test?

A
  • Stressor: exercise or pharmacologic
  • Imaging modality: EKG, Echo, Nuclear (myocardial perfusion imaging - MPI)
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19
Q

Exercise (2 imaging tests) vs Pharmacologic (drug) as stressor

Imaging for each type?

A
  • Exercise as Stressor - PREFERRED
    • EKG imaging only = Exercise Tolerance Test (ETT) Level 1 stress test
    • Nuclear imaging = Treadmill Nuclear Stress Test
  • Pharmacologic as Stressor (drug)
    • Always includes either nuclear or echocardiogram imaging
    • NOT EKG monitoring
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20
Q

Best way to stress the heart?

A

EXERCISE PREFERRED

21
Q

When should a patient not utilize exercise as a stressor?

Limitations

A
  • Not able to exercise to 85% of age-predicted max HR
  • On BB or other AV blocking agents inhibiting HR increase needed
    • Take these off - sensitivity to detect coronary stenosis reduced

Consider these patients for pharmacologic stress testing

22
Q

Can your patient exercise to a satisfactory level?

Algorithm

A

If pt on BBs or other AV blocking agents, or have any conditions (LBBB, paced rhythm) that would inhibit HR increase needed to achieve stress or reduce stress test sensitivity → YES → Pharmacologic

Need to be mental and physical limitations (respiratory, elderly, dementia)

23
Q

What do you always need before a stress test?

A

Baseline EKG

24
Q

Bruce Protocol vs Modified Bruce Protocol (treadmill)

A
  • Bruce Protocol - most common in office-based testing - extensively validated
  • Modified Bruce Protocol - can be used in patients unable to complete Bruce protocol - going slowly
25
Q

Who needs a Pharmacologic Stress Test?

A
  • Any patient unable to exercise to a satisfactory workload
  • Patients w/baseline LBBB or ventricular pacing
    • Electric pathway not in line - make sure heart is getting adequate perfusion - need more tracing
26
Q

Does Pharmacologic Testing include imaging?

A

YES

27
Q

What kind of meds are involved in pharmacologic stress test?

A

Vasodilating agents

Ionotropes/chronotropes

28
Q

Vasodilating agents

MOI

A
  • Increase coronary blood flow by acting on Adenosine receptors in heart - primarily A2A
    • When activated these receptors result in vasodilation
    • Also present in brain, lungs, spleen
  • Preferred agents for stress testing
  • Can be combined w/low level exercise → decrease SEs from vasodilator + provide better assessment of exercise capacity
29
Q

Vasodilating agents: which drugs

A

Adenosine

Regadenosen (selective for A2A receptors - best tolerated)

Dipyridamole (long ½ life; not used as frequently)

30
Q

Vasodilating agents

Contraindications

A
  • Significant reactive airway disease such as asthma (acting on beta receptors)
  • Significant HoTN
  • High degree AV block
  • Unstable or complicated ACS
  • Theophylline and caffeine should be withheld prior to vasodilator stress
    • Theophylline hold for 48 hours; caffeine for 12 hours
31
Q

Dobutamine

A
  • (+) ionotrope and chronotrope → stimulates beta1 and beta2 receptors
  • Rapid onset (1-2m) + short half-life
  • Can be given w/ atropine to achieve target heart rate if needed
  • Preferred agent in stress echos: 2nd in MPI - nuclear
32
Q

Dobutamine

contraindications

A
  • Sustained arrhythmias or Afib w/RVR
  • Recent MI/unstable angina
  • Aortic dissection
  • Moderate to severe HTN (SBP > 180)
33
Q

Purpose of imaging the heart

A
  • Helps determine whether inducing stress (using exercise or pharmacologic agents) caused myocardial ischemia → significant coronary stenosis
  • Imaging types: EKG, Echo, Nuclear
34
Q

Which test(s) require a cardiac stress agent?

A

Nuclear stress/stress echo

35
Q

Does the patient have an abnormal baseline EKG?

Yes → then what?

No → then what?

A
  • No → ETT
  • Yes → add imaging to stress
36
Q

List of abnormal baseline EKG reading conditions

A
  • LVH - any wall abnormalities - echo (structural)
  • LBBB
  • Paced rhythm
  • WPW syndrome
  • ST-T wave changes > 1mm
  • On digoxin
  • Hx of revascularization, angiography
37
Q

Nuclear Exercise Stress Test

What

A
  • Stress radionuclide myocardial perfusion imaging (rMPI)
    • Single photon emission CT (SPECT) - common IMAGE
    • Can be used in exercise MPI or pharmacologic MPI

OR

  • Positron emission tomography (PET) - more exepensive
    • ONLY used in pharmacologic MPI
38
Q

Nuclear Exercise Stress Test

Process

A
  • IV Radioactive tracer administered → wait 30m → RESTING pictures taken 1st
  • Exercise/stress inducer starts → 2nd tracer administered → STRESS pictures taken
  • Total time 2-3hrs → longer than ETT
  • Compare REST VS STRESS pictures → see how well heart is perfused → cardiologist interprets this
39
Q

SPECT imaging interpretation

A
  • Gamma radiation measured directly
  • Images after 45 minutes of rest are compared to stress images
  • Nuclear imaging - “cold spot” areas are considered areas of low or no blood flow → less activity
  • Interpretation based on rest images
    • Re-perfused (ischemic area) → reversible defect
    • Fixed defect (infarct area)
40
Q

ETT

Imaging vs. W/o imaging

A
  • W/o imaging
    • Provides ONLY EKG tracings
    • Acceptable for most patients who are able to exercise
  • W/imaging
    • Provides EKG TRACING and IMAGING
    • More sensitive
      • For pt who is ABLE TO EXERCISE w/any of following
        • WPW (ventricular pre-exication)
        • ST-T wave changes
        • LVH
        • On digoxin
        • Requires ischemia localization or assessment of viability
41
Q

Stress test preparation (7 things)

A
  • NPO 4hrs prior
  • No caffeine for 24hrs prior
  • Meds to hold day of test: Isosorbide, NTG, BBs, CCBs
  • No smoking 4hrs prior
  • No exercise day of test
  • Comfortable shoes and clothing (no jumpsuit)
  • No lotions to help electrodes stick
42
Q

Two types of echocardiogram

A
  • Transthoracic Echocardiogram (TTE) → on side, external
  • Transesophageal echocardiogram (TEE) → going into behind the heart → need sedation

Can have both done to get bigger picture of heart. Both dependent on skill level of technician

43
Q

Echocardiogram indications

A
  • Structural evaluation
    • Pericardium (pericardial effusion)
    • Ventricles (hypertrophy, dilation, wall motion abnormalities, visualize thrombi)
      • Pumping appropriately
    • Valves (stenosis, prolapse
    • Great vessels (aortic dissection)
    • Atria and septa between chambers (congenital heart disease, trauma)
  • Hemodynamic evaluation - blood flowing and how it’s flowing
    • Blood flow through valves (stenosis, regurgitation)
      • Stenosis - blood not able to get through (only a little)
      • Regurgitation - goes through but comes back
    • Blood flow through chambers (ejection fraction)
      • How efficient the heart is pumping and how it’s pumping out
44
Q

Conditions to order an Echo for (8)

A
  • New or monitoring
    • Valvular disease (suspected)
    • CHF
    • LVH/cardiomyopathy
    • New afib - look at valves
    • Pulmonary HTN (suspected)
    • Post ACS/pts w/CAD - remodeling of heart structure
    • Congenital heart disease
    • Endocarditis or thrombus or tumor
45
Q

TTE

A
  • Most common
  • Less invasive with no prep
  • Image quality affected by amount of tissue between transducer and chest
  • Difficult to see posterior images
46
Q

TEE and indications

A
  • Clearer image - behind heart, not as optimal for front of heart
  • Sedation
  • Fasting 4-6hrs prior
  • Esophagus can restrict transducer position
  • Indications
    • Concern for infective endocarditis/complications of
    • Suspected acute aortic pathology
    • IF TTE non-diagnostic w/high suspicion for cardiac etiology
    • Complex congenital disease
47
Q

Bubble study

Testing for?

Risk of having this?

A

Shake saline and pump BUBBLE into vein → if they see bubble travel to other side of heart (go into LV) - Patent Foramen Ovale

+PFO → clot → stroke

48
Q

Stress echocardiogram

Purpose + Process

A
  • Stress test + ECHO
  • Allows eval of cardiac function to see if parts of heart not getting perfused
    • Real-time eval of cardiac function from exercise
    • Echo before and after exercise
  • Same considerations and patient selection criteria
  • Rest echo → Treadmill, bicycle, or pharmacologic stress → immediate post-exercise echo
49
Q

Stress Echo indications

A
  • THINK STRUCTURE OF HEART
  • Detection and eval of intra-ventricular gradients in hypertrophic cardiomyopathy
    • See how blood flow is through valves
    • Can see ischemic changes
  • Eval of LV wall motion abnormalities
  • Eval pulmonary HTN, mitral regurgitation, mitral stenosis during exercise w/pulmonary artery systolic pressure - help w/surgical decision
  • Can see ischemic changes w/ventircular hypokinesis, akinesis, or dyskinesis