CARDIAC ENZYME Flashcards
Also called as Cardiac biomarker
CARDIAC ENZYMES
Other name cardiac function test
CARDIAC ENZYMES
Increase in the myocardial necrosis and the enzymes will release in the circulation
CARDIAC ENZYMES
Following characteristics of CARDIAC ENZYME:
o Appear Early
o Accurate
o Easily detected
o Specific
Enzyme nomenclature of Creatine Kinase
EC 2.7.3.2
Involved in energy storage of tissues (muscle)
Creatine Kinase
Dimeric molecule of Creatine Kinase
B (Brain Type)
M (Muscle Type)
It catalyze the transfer of a phosphate group between creatinine phosphate and adenosine diphosphate
Creatine Kinase
Creatine Kinase is very sensitive indicator of
acute myocardial infarction AMI and Duchenne disorder
Not specific marker of cardiac arrest (heart)
Creatine Kinase
Highest elevation of Total CK is seen in
Duchenne’s muscular dystrophy
Cofactor of CK
MAGNESIUM
CK majority location in
Skeletal Muscle, Heart muscle and Brain
Ck minority location in
Bladder, Placenta, GIT, Thyroid, Uterus, Lung, Prostate, Spleen, Liver and Pancreas
Dominant in brain, intestine and smooth muscle
CK1 or CK-BB