Cardiac emergencies Flashcards
What TnI low likelihood of mycoardial necrosis?
< 40 ng/L
What TnI high likelihood of myocardial necrosis?
TnI > 100 ng/L
What are criteria for STEMI?
Cardiac sounding chest pain with persistent STsegment elevation (or new LBBB) on ECG
ST elevation should be >1mm in limb leads and 2mm in chest leads
Subsequent TnI will be >100 ng/L
What are criteria for NSTEMI?
Cardiac sounding chest pain
ECG may show ST segemnt depression, T wave inversion or may be normal
Subsequent TnI will be >100 ng/L
Previously established ECG changes such as old MI, LV hypertrophy or AF may be present
Hallmark of ACS is labile ECG changes
What are criteria for unstable angina?
Cardiac sounding chest pain
ECG may show STsegment depression, T wave inversion or may be normal
Subsequent TnI <40 ng/L
Initial management of STEMI?
Oxygen
Morphine
Aspirin 300mg chewable
Prasugrel
What is target BP for patients with CAD?
130/80
Signs of cardiogenic shock (LVFwith hypotension)?
CO low, dyspnoea may not be dominant Systolic < 90 Pale, drowsy, cool peripheries, oliguria JVP elevated Gallop rhythm
Management of cardiogenic shock?
High O2
Diuretics
Inotropes, including dopamine and dobutamine
Pharmacodynamics dopamine?
Low dose (2.5 -5 mcg/kg/min): Dopaminergic receptors producing dilatation renal, coronary, splanchnic and cerebral arteries High dose (5-15 mcg/kg/min): B1 receptors activated with positive inotropic and chronotropic effects
Pathophysiology of MR post MI?
Annular dilatation secondary to LV dysfunction
Papillary muscle dysfunction/rupture following inferior MI (posteromedial papillary muscle is supplied by the posterior descending artery branch of the RCAor circumflex)
Presentation of MR post MI?
2-7 days post MI
Severe orthopnoea + PND
Hypotension
Large pansystolic murmur at apex/LSE
Definition HF?
Heart unable to maintain sufficient cardiac output to meet metabolic demands of the body despite normal venous filling pressures
How to calculate ejection fraction?
EF = (EDV - ESV) / EDV