Cardiac Drug Card Flashcards
Class, effect and administration of dobutamine
Beta 1 agonist
Increases contractility and HR
Administered via peripheral line if no central line is available
Class, effect and administration of Milrinone
- Phosphodiesterase inhibitor
- Increases cAMP to increase cardiac contractility, decrease PVR and decrease SVR/BP
- Administered via central line always
Indications of milrinone
- Low EF/cardiac output
2. Pulmonary hypertension
Class, effect and administration of epinephrine
- Alpha and beta agonist
- Increases contractility, HR and BP
- Central line if possible
Class, effect and administration of dopamine
- Dopaminergic agonist, alpha and beta agonist
- Renal vasodilation, inc HR, inc BP
- Administered centrally always!!!
Renal vasodilation dose for dopamine
2-5 mcg/kg/min
Dopamine dose for inc HR
5-10 mcg/kg/min
Dopamine dose for inc BP
> 10 mcg/kg/min
Class, effects, administration of Levophed
- Alpha and beta agonist
- Powerful vasoconstriction on alpha receptors
- Inc contractility and HR
- Central line only!
Dosing of levophed
- 4mg in 250 mL bag for 16 mcg/mL concentration infusion
- 10 mL syringe of 16 mcg/mL bolus, 0.25-1L mL (4-16 mcg) bolus
Dosing of vasopressin
5 vials (100 units) into 100 mL bag for 1 unit/mL
Administration of vasopressin
Central line
Indications for calcium
- Treat hypocalemia (often due to massive blood transfusion)
- Inc cardiac contractility
Difference between calcium chloride and calcium gluconate
- Calcium chloride should be given centrally, while calcium gluconate can be given peripherally
- Calcium gluconate is 1/3 as potent as calcium chloride
- Both should be given over 10 minutes
Dose of potassium chloride through central line
20 mEq/hr
Dose of potassium chloride through peripheral line
10 mEq/hr
Effects of NTG
- Dec BP, short onset, short duration
- Dec myocardial O2 demand
- Inc myocardial O2 supply
- Inc pulmonary shunting
Significance of Nipride
- More potent than NTG
- Emergency use only
- Sensitive to light, so use UV protective bag
Calcium channel blocker that is a popular alternative to nitroglycerin
Cardene
Dose of cardene bolus
5mg (2mL) placed into 8mL NS (0.5mg/mL concentration)
-0.5-1mL or 0.25-0.5mg bolus dose
Dose of cardene infusion
25 mg vial into 250 mL saline (0.1 mg/mL)
infused at 5-15 mg/hr
Insulin vial concentration
100 units/mL
Insulin bolus tip
Use TB syringe
Insulin infusion tip
add 1mL (100 units) to a 100 mL bag of NS
When are antiarrhythmics given?
- Off pump CABGs prior to the surgeon lifting the heart
2. In CPB prior to cardioplegia washout
Tips for magnesium and amiodarone
Given slowly over 10 min
Amicar bolus dose
1 vial (20 mL, 5g) is drawn into 20 mL syringe 5 or 10g depending on site
Amicar infusion dose
2 vials (10 grams) into 500 mL LR infusion run at 50 mL (1g)/hr
Purpose of DDAVP
Synthetic ADH
- treat diabetes insipidus
- certain coagulopathies during surgery
Mechanism of DDAVP
Stimulates clotting factor release (vWF) from vascular endothelium and increases factor VIII concentration
What can DDAVP stand for?
Deep down arterial venous pressure
Why must DDAVP be administered slowly?
Bc of its potential to cause hypotension
Concentration and infusion rate of dobutamine
- Premixed 1mg/mL (250mg/250 mL D5W)
- 2-20 mcg/kg/min
Concentration, bolus dose and infusion rate of epi
- 16 mcg/mL (4mg in 250 mL bag)
- bolus 10-50 mcg, up to 1 mg in emergency
- infusion of 0.01-0.3 mcg/kg/min
Concentration, loading dose, bolus and infusion rate of milrinone (Primacor)
- 20 mg in 100mL D5W
- Loading 50mcg/kg
- Bolus 1-2 mg
- Infusion rate 0.375-0.75 mcg/kg/min
Concentration and bolus dose of calcium
100 mg/mL (10%)
-250 mg-1g
Concentration and infusion rate of vasopressin
1 unit/mL (100 units in 100 mL bag)
-1-6 units/hr
Concentration, bolus and infusion rate for norepi (levophed)
16 mcg/mL (4 mg in 250 mL bag)
- bolus 4-16 mcg
- infusion 0.02-0.2 mcg/kg/min
Concentration and infusion rate for phenylephrine
80 mcg/mL (20 mcg/250 mL)
10-100 mcg/min
Concentration, bolus dose and infusion rate for NTG
100 mcg/mL
- 10-100 mcg
- 0.1-2 mcg/kg/min initial and up to 5mcg/kg/min max
Nipride concentration, bolus dose and infusion rate
- 2 mg/mL (50mg/250 mL bag)
- Half NTG dose for emergencies
- 0.1-2mcg/kg/min initial and up to 10 mcg/kg/min max
Cardene concentration, bolus and infusion rate
- 2.5 mg/mL in vial (0.5 mg/mL for bolus, 0.1 mg/mL infusion)
- 0.25-0.5mg (0.5-1mL)
- 5-15 mg/hr
Amiodarone concentration and bolus dose
- 50 mg/mL (3mL vial)
- 150 mg over 10 min
Magnesium concentration and bolus
0.5 g/mL
1-2g over 10 min
Insulin concentration, bolus and infusion rate
1 unit/mL (100 units/100mL bag)
- sliding scale
- 2-6 units/hr titrated PRN
Dextrose concentration, loading dose, bolus
50% dextrose (500 mg/mL) 50 mL = 25g
- 25g (1 amp 50%) loading
- 0.5g/kg (1g raises BG 3-4 mg/dl)
Amicar concentration, loading dose, infusion rate
- 10g in 500 mL LR
- 5g liberty, 10g at MAHI
- 1g/hr, continue 4hrs in ICU
Desmopressin (DDAVP) concentration, infusion rate
- 4 mcg/mL
- 0.3 mcg/kg in 50 mL NS over 20 min
Alternative to double lumen tube
Bronchial blocker
How many ports does a bronchial blocker have?
4
What is the bottom port of a bronchial blocker for?
The ETT
What is the side port of a bronchial blocker for?
Connection of the ventilation circuit
What is the top port of a bronchial blocker for?
Fiberoptic bronchoscope
What is the angled side port of a bronchial blocker for?
The actual bronchial blocker itself
What is another method for placement of a bronchial blocker?
A univent ETT
Lumen of the univent ETT for the bronchial blocker
Anterior
What is the posterior lumen of the univent ETT used for?
Ventilation and the fiberoptic bronchioscope
Disadvantage to univent ETT
You cannot ventilate the pt until the scope is removed
Which direction do you turn the bronchial blocker to block the R lung?
Clockwise
The name of the blue lumen of a double lumen tube that sits in the bronchus
Bronchial lumen
The name of the clear lumen of a double lumen tube that sits in the trachea
Tracheal lumen
What are most double lumen tubes?
L double lumen tubes where the bronchial is designed to sit in the L mainstem
Why shouldn’t you use a L double lumen tube for a R mainstem ventilation of the bronchial lumen?
The R lung has an upper lobe that wouldn’t be ventilated well by the L double lumen tube
Where does the stylet go in a DLT?
In the bronchial lumen
If the L DLT is placed and the bronchial lumen is clamped, where should you hear breath sounds?
On the R side
If a L DLT is placed and the tracheal lumen is clamped, where should you hear breath sounds?
On the L side
What is the size of the central line cordis?
8.5 F