Cardiac devices Flashcards

1
Q

What are class 1 indications for pacemaker insertion? (6)

A
  1. Complete AV block (with or without symptoms)
  2. Advanced 2nd degree AV block (block of 2 consecutive P-waves
    • Especially the ones with high-risk features: HF, pause ≥3 seconds, ventricular escape rhythm <40
  3. Symptomatic 2nd degree AV block (Morbitz type I and II)
  4. Asymptomatic Morbitz II with widened QRS or chronic bifascicular block
  5. Exercise-induced 2nd or 3rd degree AV block
  6. Sinus node dysfunction with symptomatic bradycardia (e.g. sinus bradycardia)
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2
Q

What are class II indications for pacemaker insertion? (3)

A

Asymptomatic 2nd degree AV block (Morbitz type II) with narrow QRS (if wide, class 1)

1st degree AV block with haemodynamic compromise due to effective dissociation secondary to very long PR interval

Bi/Trifascicular block with syncope where it is attributed to transient complete HB

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3
Q

What are the 3 indications for implantable cardioverter-defibrillator (secondary prevention)? (2)

A

Patients with prior episodes of…

  • Resuscitated VT/VF
  • Spontaneous sustained VT
    • In the presence of heart disease (cardiomyopathies - valvular, ischaemic, hypertrophic, dilated or infiltrative – i.e. structural disease) OR
    • Where a completely reversible cause cannot be identified (e.g. idiopathic VT/VF, congenital long QT)
    • Not VT/VF occurring within 48 hours following MI
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4
Q

Indications for ICDs in the setting of primary prevention? (3)

A

Basically patients with high-risk of SCD due to VT/VF despite optimal medical management (ACE and beta-blockers for ≥3 months), including patients with…

  1. Prior MI (but at least ≥40 days ago) + LVEF <30%
  2. Cardiomyopathy + NYHA 2-3 + LVEF <35%
  3. High-risk congenital disorders: HOCM, ARVC, Long-QT, Brugada and chanelopathies
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5
Q

What is the minimum length of expected survival / functional status for someone being considered for ICD insertion?

A

1 year

Acceptable functional status

This is even if they otherwise meet the criteria

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6
Q

What are the contraindications to ICD insertion? (5)

A
  1. Expected survival <1 year with poor functional status
  2. Completely reversible causes (e.g. electrolyte imbalance, drugs)
  3. Infection (but can bridged with wearable cardioverter/defib - WCDs)
  4. Severe psychiatric illnesses (that could be aggravated by device - rare)
  5. Where other therapies should be considered first, where the risk of SCD is normalized after a successful procedure (Catheter ablation, Surgical intervention)
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7
Q

5 things that determine indication for CRT?

A

LVEF

QRS duration

QRS pattern

NYHA

Need for ventricular pacing

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8
Q

What are the class 1 indications for CRT?

A

LVEF ≤ 35%

Wide LBBB150ms (i.e. ≥ 4 small squares)

NYHA class II to IV symptoms

Decision regarding CRT vs ICD based on age/cormorbidities

Other indications are there, but a lot less robust evidence – such as (basically meets only 1 of the above criterias)

QRS >150 with non-LBBB

QRS 120-149 with NYHA III-IV + recurrent HF

LVEF 35-50% but long QRS + III-IV symptoms

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9
Q

What are the names of (2) trials that showed that patients with RBBB, QRS <120 ms are much less likely to benefit, and often do worse even if LVEF <35%?

A

ReThinkQ

LESSER-EARTH

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10
Q

Would you consider CRT in patient with AF who otherwiese meet the criteria?

A

It is much more difficult to enforce biventricular pacing → at this stage, they do not fulfill the criteria

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11
Q

What are the risks/disavantages associated with CRT that must prompt you to consider before putting it in? (6)

A
  1. CRT implantation is longer + entails more procedural risk
  2. Increased risk of infection c/w ICD or PPM insertion
  3. LV leads leads have higher risk of dislodgment or pacing phrenic nerve compared with traditional RV leads
  4. Shorter battery longevity
  5. Not all will have the same benefits despite same indications (non-responders) – i.e. in preventing hospital admissions or improving LVEF
  6. Negative responders” – actually becomes worse
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12
Q

What are the factors (radiographic/ECG/symptom features) associated with less benefit from CRT? (4)

A

Greater scar burden – by MIBI or Cardiac MRI

Non-LBBB

QRS <150

Milder symptoms

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13
Q

What are the implications of having severe COPD or CRF in considering CRT?

A

If symptoms predominantly derived by COPD – less benefit

Severe CKD – less benefit and higher risk of device-related infection

Especially if the patient is on HD - ↑ risk of bacteremia, endovascular lead infection, hematoma, compromisation of vascular access, limited access to placement

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14
Q

What are the contraindications for CRT? (3)

A

Similar to ICD such as active bloodstream infection

Frailty or comorbidities that limits expected survival with good functional capacity <1 year

Anaesthetic concerns

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15
Q

Pacemaker modes - VVI or VVI (R)?

What does it mean?

Main indication (1)

Main problem (1)

A

VVI

  • ventricular pacing and sensing
  • if no electrical impulse sensed then pacemaker will pace @ a pre-programmed rate
  • if electrical impulse sensed then pacing inhibited

Main indication = AF with slow ventricular response. Advantage = prevents bradycardia.

Main problem = ventricular pacing cannot maintain AV synchrony, which can lead to pacemaker syndrome.

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16
Q

Pacemaker mode - AAI (AAIR) pacing

What is it?

Indication

Problem?

A

AAI

  • atrial pacing and sensing
  • if no electrical impulse sensed then pacemaker will pace @ a pre-programmed rate
  • if electrical impulse sensed then pacing inhibited

Appropriate for patient with sinus node dysfunction (e.g. sinus pauses, sinus bradycardia), but who have intact AV node (so no ventricular pacing needed).

Main problem: unlike VVIs, they will not protect patient from ventricular bradyarrhythmias due to AV conduction block. As many patients who has SND later develop AV conduction disease, it is not frequently used.

DDD

both atrium and ventricle both sensed and paced

if both SA and AV node functioning then pacemaker will just sense

if either atrium or ventricle not conveyed → pacemaker will take over

17
Q

Pacemaker modes - DDD (DDDR)

Indications

A

Dual-chamber pacing - provides physiologic pacing.

  • both atrium and ventricle both sensed and paced
  • PM is inhibited if both SA and AV node functioning (produces normal SR in ECG)
  • If SA down, AV working → atrial pacing, followed by native QRS
  • If SA working, AV down → ventricular (synchronously with atrium) pacing only
  • If both SA/AV down → AV sequential pacing (both are paced)

Appropriate for patients with

  • Combined SA + AV dysfunction
  • SND + normal AV
18
Q

What is difference between Cardioversion vs. defibrillation?

A

Cardioversion is synchronised shock delivered at the peak of R

  • VT is organised electrical rhythm
  • Delivery of shock during vulnerable period of repolarisation → degeneration to VF

Defibrillation is unsynchronised shock (i.e. randomly during the cardiac cycle)

  • Used for very rapid VT/VF (i.e. >200)
  • VF is not organised rhythm
  • So synchronised cardioversion is not possible nor necessary
  • Hence this is where debrillator function come in.
19
Q

What is are the option for patients who are at risk of SCD but does not meet criteria for implanted ICD (e.g. due to active infection)? (2)

A
  1. Wearable Cardioverter-Defibrillator (WCD)
  2. Subcutaneous ICD (S-ICD)
20
Q
A
21
Q

Disadvantage of S-ICD c/w standard transcutaneous ICD?

A

No capability for continuous pacing

So cannot be used for patients requiring pacing or anti-tachycardia pacing, or CRT

22
Q

What are the DDx for ICD “firing”?

A
  1. Device malfunction: fractured or dislodged leads, loss of capture after ICD shock, redundant loops of endocardial leads
  2. Lead infection
  3. SVT with RVR: majority have algorithms to differentiate VT vs SVTs but still can happen. Options are a) Re-program, b) Treat SVT – e.g. ablation
  4. Device oversensing (e.g. NSVT, QRS double counting)
  5. Phantom shock (they feel it but shock did not happen)
  6. Appropriate delivery (intended response)
23
Q

What is your approach in investigating patient with ICD “firing-off”?

A

T: Run a device check / data / programming - review for VT/VF/SVT

E: inflammatory markers, temperature chart, septic screen, CXR (?lead dislodgement or #), work-up for ischaemia (ECG, TTE, MIBI, Cath)

S: screen complication - CXR (HF)

24
Q
A
25
Q

Patient is experiencing frequent shocks. Having excluded ischaemia and other serious causes, patient asked for it to be removed. What are the options?

A

introduce or increase antiarrythmic - amiodarone or beta-blockers

Consider ablating VT

26
Q

Recently inserted device, p/w HF. What is an important diagnosis to exclude?

A

Tricuspid regurgitation resulting from placement of leads damaging TV → impeding closure of TV during systole