cardiac cycle Flashcards

1
Q

what are the phases of heart beat?

A

diastole

systoles

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2
Q

what is diastole?

A

lasts 2/3 of each beat
ventricle relax
blood passively flows into the ventricles
(4 phases)

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3
Q

what is systole?

A

lasts 1/3 of each beat
ventricles contract
generate pressure then eject blood into arteries
(3 phases)

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4
Q

what is the end diastole volume?

A

maximum blood that can be held by a ventricle before contraction
120ml average

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5
Q

what is the end systolic volume?

A

volume of blood left after contraction

50ml average

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6
Q

what is the stroke volume?

A

end diastole volume - end systolic volume

average 70ml

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7
Q

what is ejection fraction?

A

100 x stroke volume/end diastolic volume

(58% average) 52-72% normal range

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8
Q

what is the cardiac cycle (all 7 steps)

and what phase do they belong to? (d-diastole, s-systole)

A
atrial systole d
isovolumetric contraction s
rapid ejection s
slow ejection s
isovolumetric relaxation d
rapid passive filling d
slow passive filling d
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9
Q

outline atrial systole step

A

P-wave is the start of atrial systole
Atria already almost full from passive filling driven by pressure gradient. Atria contract to ‘top-up’ the volume of blood in ventricle

4th heart sound – abnormal, occurs with congestive heart failure, pulmonary embolism or tricuspid incompetence

atrial pressure is higher than ventricle

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10
Q

outline isovolumetric contraction

A

QRS complex marks the start of ventricular depolarisation

This is the interval between AV valves (tricuspid & mitral) closing and semi-lunar valves (pulmonary & aortic) opening

Contraction of ventricles with no change in volume

1st heart sound (‘lub’) due to closure of AV valves and associated vibrations

pressure inside ventricle increases

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11
Q

outline the rapid ejection phase

A

Opening of the aortic & pulmonary valves mark the start of this phase

As ventricles contract pressure within them exceeds pressure in aorta and pulmonary arteries. Semilunar valves open, blood pumped out and the volumes of ventricles decrease.

No heart sounds for this phase

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12
Q

outline the reduced ejection phase

A

This phase marks the end of systole

Reduced pressure gradient means aortic & pulmonary valves begin to close

Blood flow from ventricles decreases and ventricular volume decreases more slowly

As pressures in ventricles fall below that in arteries, blood begins to flow back causing semilunar valves to close

Ventricular muscle cells repolarize producing T wave

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13
Q

outline the isovolumetric phase

A

The aortic & pulmonary valves shut, but the AV valves remain closed until ventricular pressure drops below atrial pressure.

Atrial pressure continues to rise. Dichrotic notch (green line) caused by rebound pressure against aortic valve as distended aortic wall relaxes.

2nd heart sound (‘dub’) due to closure of semilunar valves and associated vibrations

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14
Q

outline the rapid passive filling phase

A

Occurs during isoelectric (flat) ECG between cardiac cycles

Once AV valves open blood in the atria flows rapidly into the ventricles.

3rd heart sound – usually abnormal and may signify turbulent ventricular filling
Can be due to severe hypertension or mitral incompetence

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15
Q

outline the reduced passive filling phase

A

This phase can be called diastasis

Ventricular volume fills more slowly

The ventricles are able to fill considerably without the contraction of the atria.

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16
Q

compare pressures in the right and left side of the heart

A

The patterns of pressure changes in the right heart are essentially identical to those of the left
Quantitatively, the pressures in the right heart and pulmonary circulation are much lower (peak of systole – 25mmHg in pulmonary artery)
Despite lower pressures right ventricle ejects same volume of blood as left (it is simply pumping the same quantity of blood into a lower pressure circuit)!

17
Q

what is the ESPVR?

A

end-systolic PV line

active force

18
Q

what happens to stroke volume when preload is increased?

A

it increases

frank-starling relationship

19
Q

what happens to stroke volume when afterload is increased?

A
it decreases
(less shortening as working against an increased afterload)
20
Q

what is cardiac output?

A

heart rate x stroke volume

21
Q

what is contractility?

A

strength of contraction or capability of contraction

22
Q

what increases contractility?

A

sympathetic stimulation

changes cyclic AMP in myocytes and changes calcium delivery