Cardiac conditions Flashcards

1
Q

Heart failure risk factors

A

HIGH VIS
Hypertension
Infection/immune
Genetic
Heart attack
Volume overload - renal failure, nephrotic syndrome, liver failure
Infiltration- sarcoidosis
Structural- valvular heart disease
Diabetes
Smokers

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2
Q

Heart failure symptoms

A

Dyspnoea
Paroxysmal nocturnal dyspnoea
Poor exercise tolerance
Fatigue
Orthopnea
Wheeze
Cold peripheries
Weight loss
Syncope

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3
Q

Heart failure signs

A

Raised JVP
Ankle swelling- peripheral oedema
Wheeze
Gallop rhythm on auscultation
Displaced apex beat (due to LV dilatation)
Murmurs associated w/ valvular heart disease
Tachycardia

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4
Q

Heart failure investigations

A

Clinical Exam
N terminal pro B type natriuretic peptide. BNP.
ECG- broad QRS is main sign for hypertrophy
Echocardiogram- provides info relating to ejection fraction of LV
Cardiac MRI
CXR: ABCDE: Alveolar oedema, kerley B lines, Cardiomegaly, Dilated upper lobe vessels, Effusions

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5
Q

Heart failure management principles

A

RAMPS:
Refer to cardiology
Advise them about condition
Medical treatment
Procedural or surgical interventions
Specialist heart failure MDT treatment

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6
Q

Heart failure medical management (HFrEF)

A

ABAL
ACE inhibitor- ramipril
Betablockers- Bisoprolol
Aldosterone receptor antagonist - spironolactone
Loop diuretics- furosemide

Can give digoxin, vasodilators, SGLT2 inhibitors

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7
Q

Heart failure further management (not medical)

A

Implantable cardiac defibrillators
CRT- pacemaker device
Heart transplant

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8
Q

Heart failure types

A

HF with preserved LV function (EF>50%), or HF w/ LV systolic dysfunction (EF <40%)

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9
Q

Heart failure w/ preserved LV function (ejection fraction >50%) treatment

A

treat underlying cause
lifestyle changes
diuretics for symptom control

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10
Q

Acute heart failure signs and symptoms

A

rapid onset dyspnoea
cough w/ frothy white/pink sputum
swelling in legs, ankles and feet
rapid/irregular heartbeat
tachypnoea
low O2 sats
raised JVP
bilateral basal crackles
displaced apex beat
S3- heart sound

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11
Q

acute heart failure diagnosis

A

Use a single measurement of BNP or NtpBNP to rule out HF diagnosis:
BNP less than 100 ng/litre
NTpBNP less than 300 ng/litre

W/ raised BNP lvls, perform transthoracic Doppler 2D echocardiography

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12
Q

acute heart failure management

A

Stop IV fluids
Sit pt upright
High flow oxygen if decreased SpO2
IV access and monitor ICG
Investigations
Furosemide 40-80mg IV slowly
If systolic BP >=100 mmHg, start a nitrate infusion
If pt is worsening give further dose of furosemide
Consider CPAP if resp failure or reduced consciousness or physical exhuastion, helps keep alveoli open
Other potential measures:
Diamorphine
GTN spray
Monitor fluid balance
If systolic BP =< 100 mmHg treat as cardiogenic shock and refer to ICU

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13
Q

AF categories

A

Paroxysmal- episodes last
>30 s but <7 days and are self terminating but recurrent
Persistent: episodes last less than or more than 7 days but require cardioversion
Permanent: episodes fail to termiante w/ cardioversion OR a termianted episode that relapses within 24 hrs OR long standing AF (usually >1 year) in which cardioversion has not been indicated or attempted

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14
Q

AF causes

A

Hypertension
Obesity
Alcohol
HF
Atrial/ventricular dilation or hypertrophy
inflammatory condition
Diabetes
PE
electrolyte imbalance
acute infection

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15
Q

AF risk factors

A

Male
Caucasian
Age
Alcohol
Cigarette smoking
Obesity

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16
Q

AF symptoms

A

Dyspnoea
Chest discomfort
Palpitations
light headedness
reduced ETT (exercise tolerance test)
Syncope

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17
Q

AF signs

A

raised JVP
added heart sounds on auscultation (gallop rhythm)
crackles on chest auscultation
ankle swelling

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18
Q

AF investigations

A

12 lead ECG- irregularly irregular rhythm, absent p waves, chaotic baseline

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19
Q

AF management

A

Rhythm control for pts w/ new onset AF, reversible cause- electrical cardioversion, pharmacological cardioversion by flecainide or amiodarone, beta blocekrs eg bisoprolol are first line for long term rhythm control

Rate control for pts w/ AF onset >48 hours. Tend to be in elderly or comorbidities. Rate control should be offered first line if AF is NOT acute
Beta blocker or rate limiting CCB (eg diltiazem)
If one drug doesn’t work, do combo therapy w/ any 2 of the following : BCD
Beta blocker- common contraindication is asthma
CCB- verapamil, diltiazem
Digoxin if person does little physical exercise
Paroxysmal AF= pill in pocket- flecainide PRN.
DVLA- can drive cars if controlled for > 4 weeks
Smoking cessation
Counsel on stroke risk, support groups

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20
Q

Infective endocarditis risk factors

A

previous IE
Rheumatic fever
recent prosthetic valve surgery
IV drug use

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21
Q

IE causes

A

commonest cause- streptococcus viridans
staph aureus
MRSA (methicillin resistant staph aureus)

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22
Q

IE symptoms

A

Fever
New murmur
high temperature
chills
headache
myalgia
arthralgia

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23
Q

IE signs

A

Petechial rash
Splinter haemorrhages
Osler nodes
Janeway lesions
Roth spots
digital clubbing
new murmur
signs of IV drug use
any sternotomy or thoracotomy scars suggesting previous cardiac surgery

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24
Q

IE diagnosis

A

Transthoracic echo is first line imaging modality

Modifeid Duke criteria- requires either 2 major, 1 major 3 minor, 5 minor.
Majors:
Blood culture positive for IE
Positive echo for IE
Minors:
predisposition, IV drug abuse, fever, vascular phenomena, immunlogic phenomena, microbiological evidence

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25
IE treatment
ABx in line w/ trust policy Surgery if: Heart failure- urgent surgical valvular replacement valvular obstruction persistent bactaraemia myocardial abscess Regerral to endocarditis MDT
26
Aortic stenosis causes
senile calcification bicuspid aortic valve rheumatic heart disease
27
aortic stenosis symptoms
symptomatic fluid overload (dyspnoea/orthopnea/peripheral oedema) Chest pain Dizziness faints
28
aortic stenosis signs
slow rising pulse w/ narrow pulse pressure. slow rising pulse usually noticeable at carotids. LV heave Heaving and undispalced apex beat Harsh ejection systolic murmur heard at left sternal edge: loudest leaning forward on end expiration. Murmur may radiate to both carotids and is often ehard widely across the chest. Crescendo-decrescdendo. Decreased following Valsalva manouevre
29
aortic stenosis investigations
ECG- LV hypertrophy (deep S waves in V1 and V2, tall R waves in V5 and V6) Echocardiohram- diagnostic
30
aortic stenosis treatment
if asymptomatic observe diuretics to improve symptoms surgical aortic valve replacement or transcatheter aortic valve insertion
31
aortic stenosis treatment
if asymptomatic observe diuretics to improve symptoms surgical aortic valve replacement or transcatheter aortic valve insertion
32
aortic regurgitation causes
Rheumatic fever IE connective tissue diseases biscuspid aortic valve aortic dissection
33
aortic regurgitation features
early diastolic murmur- intensity increased by the handgrip manouevre. Heard at lower left sternal edge, sat forward breath held in expiration. Collapsing pulse Wide pulse pressure Quincke's sign (nailbed pulsation) De Musset's sign (head bobbing)
34
aortic regurgitation management
surgery indications include: Symptomatic patients w/ severe AR Asymptomatic patients w/ severe AR who have LV systolic dysfunction
35
ACS symptoms
Acute sudden crushing pain radiating to jaw, neck or left arm Exertional pain worsened by stress and exertion Dyspnoea N&V Palpitations Sweatiness and clamminess Symptoms should continue at rest for over 15 mins
36
ECG change in STEMI
ST segment elevation >1mm in adjacent limb leads (I, II, III, aVF, aVL) ST segment elevation >2mm in adjacent chest leads (V1-V6) New LBBB w/ chest pain or suspicion of MI
37
ECG changes in NSTEMI
ST segment depression in a region Deep T wave inversion/flattening present in more than 2 continuous leads that have dominant R waves
38
ECG changes in usntable angina
Abnormal/normal ECG, normal consistent troponin. Ie no biochemical evidence of ischaemia
39
STEMI management
PCI always- blocked arteries are opened up using a balloon following which a stent may be deployed to prevent the artery occluding again in the future. This is done via a catheter inserted into either the radial or femoral artery. Consider thrombolysis if > 2hrs, using agents like alteplase/streptokinase if PCI is unavailable Aspirin and second antiplatelet before PCI tho
40
NSTEMI management
BATMAN Beta blockers Aspirin Ticagrelor/clopidogren Morphine IV Antithrombotic eg fondaparinux (LMWH alternative) Nitrates- GTN sublingual or buccal Assess need of PCI/thrombolysis using the GRACE score, use CRUSADE score for assesment of risk of bleeding during PCI while being on anti platelet therapies
41
Long term ACS management
Stop smoking reduce alcohol cardiac rehabilitation 6 A's: Aspirin 75mg OD another antiplatelet eg clopidogrel or ticagrelor 12 months Atorvastatin 80mg OD ACE inhibitor eg ramipril 10mg OD Atenolol or other B blocker Aldosterone antagonist If PCI is not preferred, or extensive left main stem disease- offer CABG
42
Complications after MI or unstable angina attack
keep in hospital for a couple days. DARTH VADER Death Arrhythmia Rupture of free wall/papillary muscles Tamponade HF VSD Aneurysm or another MI Dressler's syndrome/pericarditis Embolism or oedema Rupture of papillary muscles or Free Wall Pericarditis also
43
Stable angina features
Constricting chest pain that radiates to neck/shoulders/jaw/arms precipitated by physical exertion, relieved by rest / GTM in about 5 mins
44
stable angina investigations
Bloods, ECG, CXR, troponins CT coroanry angiography- site and degree of stenosis within coronary arteries can then be identified Need invasive coroanry angiography if CAD is v likely
45
stable angina medical management
immediate- GTN 2-5,2-5, 2 + 999 2 puffs under tongue, wait 5 mins. Baseline symptomatic relief- beta blocker and /or CCB. If CCB used as a monotherapy then use a rate limiting one like verapamil or diltiazen. BETA BLOCKERS SHOULD NOT BE PRESCRIBED W/VERAPAMIL- risk of complete heart block. secondary prevention of CVD- aspirin, ACEi, atorvastatin, already on ebta blocker
46
stable angina surgical intervention
PCI w/ coronary angioplasty-put catheter into brachial or femoral artery, feeding that up to the coronary arteries under xray and injceting contrast so the coronary arteries and any areas of stenosis are highlighted on xray CABG- involves opening the chest along the sternum causing a midline sternotomy scar, taking a graft vein from the leg (usually the great saphenous vein) and sewing it on to the affected coronary artery to bypass the stenosis
47
Aortic dissection risk factors
Hypertension pregnancy trauma cocaine known AA bicuspic aortic valve Connective tissue disorders, eg Marfan's Male Age Atherosclerotic disease
48
Aortic dissection symptoms
sudden, tearing chest pain radiating to the back dyspnoea abdo pain can be asymptomatic
49
aortic dissection signs
unequal arm pulses and BP weak or absent carotid, brachial or femoral pulse acute limb iscahemia Horner's syndrome in type A dissections (ascending aorta)- Ptosis, Miosis, Anhidrosis Hypotension New early diastolic murmur- aortic regurgitation murmur can present w/ features of dissection complications eg distended neck veins, signs of heart failure etc
50
aortic dissection investigations
ECG CXR- widened mediastinum CT angiogram of chest, abdo, pelvis- can see double lumen, entry tear, evidence of aortic dilatation MRI angiogram for futher details Classification is Stanford: Type A- involvement of proximal aorta Type B- involvement of distal aorta
51
Aortic dissection type A management
open surgery to prevent aortic rupture into the pericardium. Aortic root surgery- removal of ascending aorta w/ or w/o the aortic arch and replacement w/ a synthetic graft
52
aortic dissection type B maangement
Usually conservatively Usually bed rest and beta blockers- IV beta blockage, pain management w/ IV morphine
53
Pericarditis risk factors
age male steroid treatments
54
Pericarditis causes
idiopathic secondary to bacteria, viruses, fungi, drugs etc. Often follows a viral illness
55
pericarditis symptoms
central chest pain worse on inspiration or lying flat and relief by sitting forward pain can be constant or intermittent sharp pain Unlike iscahemic pain it's often relieved by sitting forwads and aggravated by thoracic movement, coughing and breathing Fever Tachycardia Pericardial friction rub- typically loudest at left lower sternal border
56
Pericarditis investigations
Raised WBC/CRP/ESR ECG- widespread saddle ST elevation, followed later by T wave inversion Echocardiogram can be used to diagnose a pericardial effusion
57
Pericarditis management
NSAID w/ PPI for 1-2 weeks Add colchicine 500mcg onde daily or twice daily for 3 months to reduce recurrent risk Recurrent/chronic pericarditis- novel treatment options are immunosuppressants Constrictive pericarditis - final stage of inflammation involving the pericardium definitive treatment is usually surgical pericardiectomy (resection of the pericardium)
58
Pericardial effusion symptoms
chest pain dyspnoea orthopnea
59
pericardial effusion signs
quiet heart sounds pulsus paradoxus (abnormally large drop in BP during inspiration) Hypotension Raised JVP Classical features of cardiac tamponade- Beck's triad- Hypotension, raised JVP, muffled heart sounds
60
pericardial effusion management
treatment of underlying cause drainage of effusion where requried- needle pericardiocentesis, surgical drainage