Carcinoid

Question 0

Are they Germ cell tumors?

Answer 0

Yes. They behaved typically in a benign fashion. Strumal carcinoid is a distinct entity with thyroid tissue with Carcinoid. It is important to rule out metastatic G.I. primary

Question 1

What is a carcinoid tumor

Answer 1

It typically well to moderately differentiated neuroendocrine tumors they lack nuclear atypia, mitotic figures, and necrosis

Question 2

What is the survival for stage one disease

Answer 2

90%

Question 3

Why do they have constipation and hirsutism

Answer 3

It is thought to be due to the release of peptide YY which inhibits motility

Question 4

What is the management

Answer 4

Surgical removal with negative margins. Fertility preservation is possible

Question 5

Do you need to give octreotide preoperatively?

Answer 5

If the diagnosis is known octreotide should be given before and during the resection to prevent carcinoid crisis. Profound Flushing, extreme changes in blood pressure, bronchoconstriction, arrhythmia, confusion. During anesthesia induction

Question 6

Is there adjuvant therapy?

Answer 6

There’s no evidence to support hormonal, chemotherapy, or radiation. Octreotide sometimes be given if patient is symptomatic.

Question 7

What is a marker for carcinoid?

Answer 7

5HIAA